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Some people may have youthful DNA despite old age, study shows

The DNA of young people is regulated to express the right genes at the right time. With the passing of years, the regulation of the DNA gradually gets disrupted, which is an important cause of ageing.

23 Sep 2016

Ludwig researchers shed more light on key requirement for function of regulatory T cells

A Ludwig Cancer Research study published online September 5th in Nature Immunology illuminates a key requirement for the function of regulatory T cells—immune cells that play a critical role in many biological processes, from suppressing inflammation and deadly autoimmunity to helping tumors evade immune attack.

23 Sep 2016

Scientists find way to reverse malfunctioning protein clumps involved in ALS

In the quest to understand the driving forces behind neurodegenerative diseases, researchers in recent years have zeroed in on clumps of malfunctioning proteins thought to kill neurons in the brain and spinal cord by jamming their cellular machinery.

22 Sep 2016

Scientists identify potential new way to prevent chronic urinary tract infections

Researchers have identified a potential way to prevent chronic urinary tract infections (UTIs). Their research points to a key protein that bacteria use to latch onto the bladder and cause UTIs, according to scientists at Washington University School of Medicine in St. Louis.

22 Sep 2016

Tumour suppressor gene has greater anti-cancer activity than previously thought

New insight into the function of a gene important in the suppression of cancer is published today. Researchers at the National University of Ireland Galway have shown that the TP53 gene has even greater anti-cancer activity than previously thought.

22 Sep 2016

Scientists discover genomic alterations in pediatric relapsed ALL

A group of researchers from Columbia University, Rutgers University, and institutions in Europe and Japan have identified genomic alterations in pediatric relapsed acute lymphoblastic leukemia (ALL) that cause both therapy resistance and improved clinical response to multi-agent chemotherapy treatment.

22 Sep 2016

MSU experts pioneer pathways to new treatment options for pneumonia

Streptococcus pneumoniae likely is not a term immediately recognizable by most individuals, even if they have had unpleasant run-ins with the common bacterium. However, experts at Mississippi State University are pioneering pathways to new treatment options.

21 Sep 2016

Bile acid transporter inhibitors can prevent NASH in mice, study shows

Drugs that interfere with bile acid recycling can prevent several aspects of NASH (nonalcoholic steatohepatitis) in mice fed a high-fat diet, scientists from Emory University School of Medicine and Children's Healthcare of Atlanta have shown.

21 Sep 2016

Duke researchers discover blood markers linked to drug-resistant tumor cells

While searching for a non-invasive way to detect prostate cancer cells circulating in blood, Duke Cancer Institute researchers have identified some blood markers associated with tumor resistance to two common hormone therapies.

21 Sep 2016

UofL researchers receive NIH funding to explore how environmental exposures influence health of children

The National Institutes of Health today announced a team of researchers headed by Janice Sullivan, M.D., of the University of Louisville is among grant recipients nationwide receiving funding for a seven-year, multicenter initiative called Environmental influences on Child Health Outcomes.

21 Sep 2016

Common genetic variant reduces neurobiological benefits of exercise in mice

A new study revealed that a common genetic variant in the brain-derived neurotrophic factor gene reduces the neurobiological benefits induced by physical exercise in mice.

21 Sep 2016

Lund University stem cell researcher awarded Fernström prize for study on repairing damaged brain

Is it possible to convert a patient’s own skin cells into functioning nerve cells? Or insert healthy genes to reprogram the cells of a damaged brain? Stem cell researcher Malin Parmar at Lund University in Sweden is studying these types of issues, in close collaboration with clinical researchers.

21 Sep 2016

Study suggests interactions between distant DNA regions may impact disease gene levels

A person's DNA sequence can provide a lot of information about how genes are turned on and off, but new research out of Case Western Reserve University School of Medicine suggests the 3-D structure DNA forms as it crams into cells may provide an additional layer of gene control.

21 Sep 2016