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Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Scientists from Jerusalem and Duesseldorf have succeeded in generating induced pluripotent stem cells from a rare disorder called Nijmegen breakage syndrome (NBS) and to push these cells to become early neurons, revealing the mechanisms leading to the neurological phenotype observed in these patients.

9 Sep 2016

Scientists discover potential new genetic causes for intellectual disability

An international group of researchers has for the first time identified a set of 30 inherited recessive genes that play a role in intellectual disability (ID), a neurodevelopmental disorder that, according to the Centers for Disease Control, affects as many as 213 million people around the world.

9 Sep 2016

Novel approach may help combat kidney disease in diabetic patients

A new strategy may help halt the progression of kidney disease in patients with diabetes.

9 Sep 2016

Fruit flies hold clues to how cancerous tumors get started

A Florida State University research team, in coordination with a team from Japan, has found that the epithelial tissues that line the surfaces of organs throughout the body intrinsically have hot spots for cancerous tumors.

9 Sep 2016

Specific set of microRNAs could help diagnose and monitor IH treatment

Infantile hemangiomas (IH) are benign vascular tumors occurring in 4-5% of infants. These tumors resolve spontaneously or in response to propranolol treatment; however, they resemble other vascular anomalies and cannot be definitively diagnosed without biopsy.

9 Sep 2016

MIT biologists unravel lncRNA structure-to-function relationships

Several years ago, biologists discovered a new type of genetic material known as long noncoding RNA. This RNA does not code for proteins and is copied from sections of the genome once believed to be "junk DNA."

9 Sep 2016

Interactions between rare and common genetic variants may contribute to craniosynostosis

During the first year of life, the human brain doubles in size, and continues growing through adolescence.

8 Sep 2016

Exposure to air pollution at place of residence could be risk factor for type 2 diabetes

Exposure to air pollution at the place of residence increases the risk of developing insulin resistance as a pre-diabetic state of type 2 diabetes.

8 Sep 2016

Researchers reveal how traditional Chinese medicine helps treat various cancers

Researchers at the University of Adelaide have shown how a complex mix of plant compounds derived from ancient clinical practice in China - a Traditional Chinese Medicine - works to kill cancer cells.

8 Sep 2016

Study finds cord blood transplant recipients appear to have better outcomes against leukemia

Umbilical cord blood transplants may have advantages beyond offering an alternative stem cell source for leukemia patients without a traditional donor match, according to a study published today in The New England Journal of Medicine.

8 Sep 2016

New molecular mechanism may explain pain relieving drug’s diverse benefits

Aspirin's ability to reduce the risk of both cardiovascular disease and colon cancer has been a welcome, yet puzzling, attribute of the pain reliever that has been a mainstay in medicine cabinets for more than 100 years.

7 Sep 2016

Researchers unlock genetic code that disrupts response to breast cancer therapy

Scientists may have unlocked the genetic code that determines why many patients with estrogen receptor-positive breast cancer fail to respond to the widely used drug tamoxifen.

7 Sep 2016

Schizophrenia drug slows pancreatic tumor growth in mice

A receptor for the dopamine neurotransmitter promotes growth and spread of pancreatic cancer -- and schizophrenia drugs, which block the function of this receptor, slowed tumor growth and metastatic spread in mice, according to researchers at McGill University and the German Cancer Research Center.

7 Sep 2016

Scientists find link between antimicrobial chemicals and antibiotic-resistance genes in microbes

Antibiotic-resistant bacteria, known as "superbugs," pose a major public health threat.

7 Sep 2016

Cedars-Sinai researchers develop new way to identify patients at risk for aggressive prostate cancer

Scientists at Cedars-Sinai have developed a new way to identify which prostate cancer patients are likely to develop aggressive types of the disease even if their tumors at first appear to be lower risk.

7 Sep 2016

Twin study looks at genetic influences on key structures of the human brain

An internationally significant study of healthy twins, 65 years of age or older, has unlocked important clues about how genes influence the development of key grey matter structures, paving the way for a genetic blueprint of the human brain.

7 Sep 2016

Researchers identify epigenetic mechanism causing aberrancies in coeliac disease

Researchers at the University of Tampere discovered a mechanism causing aberrancies in coeliac disease and colorectal cancer.

5 Sep 2016

DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

The loss of CHD1, one of the most frequently mutated genes in prostate tumors, sensitizes human prostate cancer cells to different drugs, including PARP inhibitors.

5 Sep 2016

New study details design and validation of accurate screening test for detecting deadly HAIs

A new study by the Translational Genomics Research Institute details the design and validation of a low-cost, rapid and highly accurate screening tool -- known as KlebSeq -- for potentially deadly healthcare-acquired infections (HAIs), such as Klebsiella pneumoniae.

2 Sep 2016

New discovery could potentially lead to treatments for Crohn's disease

Scientists at the University of British Columbia have made a discovery that could potentially lead to treatments for a debilitating complication of Crohn's disease.

2 Sep 2016

Genes News and Research

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Scientists discover potential new genetic causes for intellectual disability

Novel approach may help combat kidney disease in diabetic patients

Fruit flies hold clues to how cancerous tumors get started

Specific set of microRNAs could help diagnose and monitor IH treatment

MIT biologists unravel lncRNA structure-to-function relationships

Interactions between rare and common genetic variants may contribute to craniosynostosis

Exposure to air pollution at place of residence could be risk factor for type 2 diabetes

Researchers reveal how traditional Chinese medicine helps treat various cancers

Study finds cord blood transplant recipients appear to have better outcomes against leukemia

New molecular mechanism may explain pain relieving drug’s diverse benefits

Researchers unlock genetic code that disrupts response to breast cancer therapy

Schizophrenia drug slows pancreatic tumor growth in mice

Scientists find link between antimicrobial chemicals and antibiotic-resistance genes in microbes

Cedars-Sinai researchers develop new way to identify patients at risk for aggressive prostate cancer

Twin study looks at genetic influences on key structures of the human brain

Researchers identify epigenetic mechanism causing aberrancies in coeliac disease

DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

New study details design and validation of accurate screening test for detecting deadly HAIs

New discovery could potentially lead to treatments for Crohn's disease

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