Genes News and Research

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Huntington's disease monkey model embodies full array of symptoms similar to human patients

Transgenic Huntington's disease monkeys display a full spectrum of symptoms resembling the human disease, ranging from motor problems and neurodegeneration to emotional dysregulation and immune system changes, scientists at Yerkes National Primate Research Center, Emory University report.

21 Jul 2016

Shared lifestyle and environment may contribute to risk of common diseases in families, study shows

Family history of disease may be as much the result of shared lifestyle and surroundings as inherited genes, research has shown.

21 Jul 2016

New study sheds light on pathogenesis of DNA lesions present in leukemia

Researchers have succeeded in shedding light on the pathogenesis of DNA breakpoints that are associated with leukemia.

20 Jul 2016

Enhancers can boost frequency of transcriptional bursting, study shows

A new study by researchers at Princeton University suggests that sporadic bursts of gene activity may be important features of genetic regulation rather than just occasional mishaps.

20 Jul 2016

Researchers find dangerous antibiotic-resistant bacteria in wastewater from broken sewer lines

University of South Florida researchers investigating the aftermath of a September, 2014 sewer line break in St. Petersburg, Florida, have found dangerous antibiotic-resistant bacteria in the untreated wastewater that gushed into neighborhoods and into Boca Ciega Bay at a rate of 250 to 500 gallons per minute.

20 Jul 2016

New virus-based method opens wide range of options to treat various diseases

The ability to switch disease-causing genes on and off remains a dream for many physicians, research scientists and patients.

20 Jul 2016

Scientists capture atomic level snapshots of how key enzyme modifies signaling proteins

Scientists have captured atomic level snapshots showing how one key enzyme modifies a protein involved in turning genes on or off inside cells. Understanding this process-which is particularly important when cells are first taking on specialized identities such as nerve cells, muscle, skin, and so on-helps explain how complex organisms can arise from a finite number of genes.

19 Jul 2016

Identifying new pathway of EZH2 gene may lead to targeted therapies for aggressive breast cancer

Scientists from A*STAR's Genome Institute of Singapore and the Cancer Science Institute of Singapore at the National University of Singapore came together to understand how EZH2, a cancer-promoting gene which is known to be involved in many types of cancers, is activated in breast cancer and lymphomas.

19 Jul 2016

Scientists identify marker that subdivides insulin-producing beta cells of the pancreas

The marker Flattop subdivides the insulin-producing beta cells of the pancreas into those that maintain glucose metabolism and into immature cells that divide more frequently and adapt to metabolic changes.

19 Jul 2016

Novel biomarkers may offer solution for detecting autologous blood transfusion in athletes

Increasing oxygen delivery to muscles can help athletes perform better and give them the edge needed to win elite competitions. One of the best ways to increase oxygen supply is through blood manipulation, undergoing a blood transfusion that provides extra red blood cells and boosts oxygen levels.

19 Jul 2016

Scientists explore black box of genome biology

Scientists at Florida State University, Baylor College of Medicine and the Broad Institute of Harvard and MIT have broken ground in a little-understood area of human genetics.

19 Jul 2016

Study finds new data about dMMR's hereditary basis in rectal cancer

Up to 15 percent of colorectal cancers show a genetic mutation known as DNA mismatch repair deficiency, or dMMR.

19 Jul 2016

Study produces most detailed picture to date of genetics underlying type 2 diabetes

The largest study of its kind into type 2 diabetes has produced the most detailed picture to date of the genetics underlying the condition.

18 Jul 2016

Bone marrow transplantation may one day be beneficial to subset of ALS, say researchers

Harvard Stem Cell Institute researchers at Harvard University and the Broad Institute of Harvard and MIT have found evidence that bone marrow transplantation may one day be beneficial to a subset of patients suffering from amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder more commonly known as Lou Gehrig's disease.

18 Jul 2016

Rare antibiotic compound detected in fungi for first time

Besides mushrooms such as truffles or morels, also many yeast and mould fungi, as well as other filamentous fungi belong to the Ascomycota phylum. They produce metabolic products which can act as natural antibiotics to combat bacteria and other pathogens. Penicillin, one of the oldest antibiotic agents, is probably the best known example.

18 Jul 2016

Researchers publish comprehensive molecular atlas of primate brain development in Nature

Researchers at the Allen Institute for Brain Science have published an in-depth analysis of a comprehensive molecular atlas of brain development in the non-human primate.

18 Jul 2016

Study reveals muscle activity of non-responders to diabetes interventions

It is widely accepted that physical exercise lowers the risk of developing diabetes. Yet in one in five participants in related studies this positive effect fails to materialize.

15 Jul 2016

Researchers develop new screening system to measure protein aggregates

Researchers from the Massachusetts Institute of Technology and Boston University have developed a system capable of quickly screening millions of yeast cells to measure protein aggregates.

15 Jul 2016

Researchers demonstrate important functional role of lincRNA in immune system

A long non-coding RNA (lincRNA) - called lincRNA-EPS - responsible for regulating innate immunity has been identified by a team of scientists at the University of Massachusetts Medical School.

14 Jul 2016

Inability to turn off genes in the brain can affect learning and memory

Every time you play a game of basketball, make a cup of coffee or flick on a light switch, you are turning on genes in your brain. These same genes typically are turned off when the activity ceases - but when that doesn't happen, damaging consequences can occur.

14 Jul 2016

Genes News and Research

Huntington's disease monkey model embodies full array of symptoms similar to human patients

Shared lifestyle and environment may contribute to risk of common diseases in families, study shows

New study sheds light on pathogenesis of DNA lesions present in leukemia

Enhancers can boost frequency of transcriptional bursting, study shows

Researchers find dangerous antibiotic-resistant bacteria in wastewater from broken sewer lines

New virus-based method opens wide range of options to treat various diseases

Scientists capture atomic level snapshots of how key enzyme modifies signaling proteins

Identifying new pathway of EZH2 gene may lead to targeted therapies for aggressive breast cancer

Scientists identify marker that subdivides insulin-producing beta cells of the pancreas

Novel biomarkers may offer solution for detecting autologous blood transfusion in athletes

Scientists explore black box of genome biology

Study finds new data about dMMR's hereditary basis in rectal cancer

Study produces most detailed picture to date of genetics underlying type 2 diabetes

Bone marrow transplantation may one day be beneficial to subset of ALS, say researchers

Rare antibiotic compound detected in fungi for first time

Researchers publish comprehensive molecular atlas of primate brain development in Nature

Study reveals muscle activity of non-responders to diabetes interventions

Researchers develop new screening system to measure protein aggregates

Researchers demonstrate important functional role of lincRNA in immune system

Inability to turn off genes in the brain can affect learning and memory

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