Genes News and Research

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Researchers develop new detection systems for genotyping DNA and RNA with naked eye

DNA polymerases are the “Xerox machines” that replicate our DNA. They must work with great precision to keep errors from creeping into our genes.

14 Jul 2016

Expanding the potential of existing cancer therapies: an interview with Dr Mark Rutstein

Cancer remains a leading cause of death worldwide, and the global cancer burden is expected to increase by 70 percent over the next two decades.

14 Jul 2016

Genes linked to Alzheimer's disease may show effects on the brain from childhood

A gene associated with Alzheimer's disease and recovery after brain injury may show its effects on the brain and thinking skills as early as childhood, according to a study published in the July 13, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

14 Jul 2016

UCLA scientists identify mechanisms of tumor resistance to immunotherapy in advanced melanoma

UCLA researchers have for the first time identified mechanisms that determine how advanced melanoma can become resistant to immune checkpoint inhibitors, a discovery that could lead to the development of new and improved treatments for the deadliest type of skin cancer.

13 Jul 2016

Sugar-binding protein galectin-9 could be new weapon to fight HIV

The ultimate impediment to a cure for HIV infection is the presence of latent, HIV-infected cells, which can reawaken and produce new virus when antiretroviral drug therapy is stopped.

13 Jul 2016

Changes in cavefish metabolism could lead to new insights into diabetes

Cavefish that live in dark caves with only sporadic access to food show symptoms similar to diabetes, but don't appear to experience any health problems.

13 Jul 2016

Researchers discover new biological pathway involved in Alzheimer's disease

Researchers have identified a new biological pathway involved in Alzheimer's disease. In experiments using fruit flies, blocking the pathway reduced the death of brain cells, suggesting that interfering with the pathway could represent a promising new strategy to treat the disease in human patients.

13 Jul 2016

Impact of diet may depend on individual’s genetic composition

If you've ever seen a friend have good results from a diet but then not been able to match those results yourself, you may not be surprised by new findings in mice that show that diet response is highly individualized.

13 Jul 2016

Researchers study how skin stem cells respond to forces

All cells share the same genetic code, no matter if they are skin or brain cells. However, these cells are exposed to very different types of mechanical environments and mechanical stresses.

13 Jul 2016

Scientists identify timing of major metabolic shift in developing neurons

Our brains can survive only for a few minutes without oxygen. Salk Institute researchers have now identified the timing of a dramatic metabolic shift in developing neurons, which makes them become dependent on oxygen as a source of energy.

13 Jul 2016

Researchers investigate role of OXTR gene in binge eating

A study by York University researcher Caroline Davis and her colleagues at the Centre for Addiction and Mental Health is the first to demonstrate that variants of the Oxytocin Receptor gene contribute to why some of us overeat or engage in episodes of binge eating.

13 Jul 2016

Italian researchers identify new variant of emerging antibiotic resistance mechanism

A team of Italian investigators has discovered a new variant of an emerging antibiotic resistance mechanism. The new variant, dubbed mcr-1.2, confers resistance to colistin, a last-resort antibiotic against multidrug-resistant Gram-negative pathogens.

13 Jul 2016

New streamlined approach to genetic testing benefits women with ovarian cancer

A new streamlined approach to genetic testing for women with ovarian cancer provides testing rapidly and affordably, allowing many more patients to benefit from personalised cancer management and their relatives to benefit from cancer prevention strategies.

13 Jul 2016

Scientists use machine learning to interpret mosquito genome

Scientists are using machine learning to identify important sequences of DNA within the mosquito genome that regulate how the insect's cells develop and behave.

12 Jul 2016

MS patients have different patterns of gut microorganisms than healthy counterparts

A connection between the bacteria living in the gut and immunological disorders such as multiple sclerosis have long been suspected, but for the first time, researchers have detected clear evidence of changes that tie the two together.

12 Jul 2016

Selfish mutant mtDNA exploits cellular defenses to cause many diseases

Mitochondrial disorders are a chameleon-like set of diseases that take many different forms and vary widely from individual to individual.

12 Jul 2016

Research on Flattop protein could provide starting point for regenerative diabetes therapies

The marker Flattop subdivides the insulin-producing beta cells of the pancreas into those that maintain glucose metabolism and into immature cells that divide more frequently and adapt to metabolic changes.

12 Jul 2016

Boy babies more likely to experience complications at birth than girls

New research led by the University of Adelaide has confirmed that boy babies are much more likely to experience potentially life-threatening outcomes at birth than girls.

11 Jul 2016

Recellularized colon model helps identify cancer driver genes involved in CRC progression

Genetic mutations are a major cause of cancer, and tracking the role of each gene in cancer pathogenesis has long been an important tool in the fight against a disease that is expected to kill more than 1.6 million people this year.

11 Jul 2016

New study identifies four subtypes of human insulin producing beta cells involved in diabetes

A new study led by nationally prominent stem cell scientist Markus Grompe, M.D., has determined the existence of at least four separate subtypes of human insulin producing beta cells that may be important in the understanding and treatment of diabetes. The findings were published online today in the journal Nature Communications.

11 Jul 2016

Genes News and Research

Researchers develop new detection systems for genotyping DNA and RNA with naked eye

Expanding the potential of existing cancer therapies: an interview with Dr Mark Rutstein

Genes linked to Alzheimer's disease may show effects on the brain from childhood

UCLA scientists identify mechanisms of tumor resistance to immunotherapy in advanced melanoma

Sugar-binding protein galectin-9 could be new weapon to fight HIV

Changes in cavefish metabolism could lead to new insights into diabetes

Researchers discover new biological pathway involved in Alzheimer's disease

Impact of diet may depend on individual’s genetic composition

Researchers study how skin stem cells respond to forces

Scientists identify timing of major metabolic shift in developing neurons

Researchers investigate role of OXTR gene in binge eating

Italian researchers identify new variant of emerging antibiotic resistance mechanism

New streamlined approach to genetic testing benefits women with ovarian cancer

Scientists use machine learning to interpret mosquito genome

MS patients have different patterns of gut microorganisms than healthy counterparts

Selfish mutant mtDNA exploits cellular defenses to cause many diseases

Research on Flattop protein could provide starting point for regenerative diabetes therapies

Boy babies more likely to experience complications at birth than girls

Recellularized colon model helps identify cancer driver genes involved in CRC progression

New study identifies four subtypes of human insulin producing beta cells involved in diabetes

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