Laboratory News and Research

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Novel theranostic agent designed for precise tumor diagnosis and therapy

A novel, intelligent theranostic agent for precise tumor diagnosis and therapy has been developed that remains as small molecules while circulating in the bloodstream, can then self-assemble into larger nanostructures in the tumor, and be activated by the tumor microenvironment for therapy guided by photoacoustic imaging.

26 Jun 2018

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

More than 60 percent of breast cancer cases involve defects in the same biochemical chain of events within cancer cells-- known as the PI3 kinase (PI3K) pathway--but efforts to develop therapies targeting this pathway have met with little success after hundreds of mostly failed clinical trials. And researchers still don't understand why.

26 Jun 2018

Microbiologists and plant scientists pinpoint genetic weakness in cholera pandemic's armor

While cholera rages across many regions of the world, a team of microbiologists and plant scientists has pinpointed a genetic weakness in the pandemic's armor, which could lead to future treatments.

26 Jun 2018

Distek’s PrepEngine Mini speeds up sample preparation by 90%

Distek Inc. is excited to release the PrepEngine Mini Sample Prep Station for assay, impurity and content uniformity applications.

26 Jun 2018

Scientists discover new kind of small-cell lung cancer

Researchers have discovered a new kind of small-cell lung cancer. The discovery paves the way for developing personalized medicine approaches to target this previously unnoticed form of the disease.

26 Jun 2018

Researchers identify novel mutation in amyloid diseases

Researchers have identified a one-of-a kind mutation in the DNA of a patient who died of transthyretin (TTR) amyloidosis, a progressive condition characterized by the buildup of abnormal deposits of a misfolded protein called amyloid in the body's organs and tissues.

26 Jun 2018

Scientists discover and characterize new toxin in cholera bacteria

The bacterium Vibrio cholerae was discovered more than 150 years ago but remains as one of the main causes of bacterial infectious disease globally, especially in low-income nations where it occurs endemic, and outbreaks of cholera disease can lead to major epidemics.

26 Jun 2018

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

A tumor's goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate.

25 Jun 2018

Eye could be a surrogate for brain degeneration like AD

Researchers from Queen's University Belfast have shown for the first time that the eye could be a surrogate for brain degeneration like Alzheimer's disease (AD).

25 Jun 2018

Scientists discover secret to success of antiviral gene

It's been known for years that humans and other mammals possess an antiviral gene called RSAD2 that prevents a remarkable range of viruses from multiplying.

25 Jun 2018

Dynamic model helps make predictions about gut microbiome

The human gut is teeming with microbes, each interacting with one another in a mind-boggling network of positive and negative exchanges. Some produce substances that serve as food for other microbes, while others produce toxins - antibiotics - that kill their neighbors.

22 Jun 2018

Researchers discover drug compound that inhibits movement of cancer cells

Fighting cancer means killing cancer cells. However, oncologists know that it's also important to halt the movement of cancer cells before they spread throughout the body.

22 Jun 2018

Minakem's new high-class production facility extends capacity to develop and manufacture HPAPI compounds

Minakem, the CDMO division of Minafin, specialized in custom development and manufacturing of building blocks, GMP intermediates and Active Pharmaceutical Ingredients, today announces it is in the final qualification run to open a new closed-controlled environment high containment production facility in August.

22 Jun 2018

Nightingale Health to analyze biomarker profiles of 500,000 blood samples from UK Biobank

Comprehensive metabolic biomarker profiles of the world's largest health database to be analyzed in 30 months.

22 Jun 2018

Distek, Inc. launches revolutionary benchtop scale bioreactor

Distek, Inc. has revolutionized benchtop scale bioreactors with the release of our BIOne 1250 bioprocess control station for both mammalian and microbial models.

22 Jun 2018

Study provides clues to how cancer cells develop resistance to chemotherapies

About half of all drugs, ranging from morphine to penicillin, come from compounds that are from - or have been derived from - nature. This includes many cancer drugs, which are toxic enough to kill cancer cells.

22 Jun 2018

Researchers outline a connection between subplate neurons and brain disorders

The disappearance of an entire brain region should be cause for concern. Yet, for decades scientists have calmly maintained that one brain area, the subplate, simply vanishes during the course of human development.

22 Jun 2018

Novel cellular pathway may clarify how arterial inflammation develops into atherosclerosis

Investigators have identified a new cellular pathway that may help explain how arterial inflammation develops into atherosclerosis - deposits of cholesterol, fats and other substances that create plaque, clog arteries and promote heart attacks and stroke. The findings could lead to improved therapies for atherosclerosis, a leading cause of death worldwide.

22 Jun 2018

First human Keystone virus infection reported

Another deadly virus called the Keystone virus that could cause serious brain infection and is transmitted by mosquito bites has been found for the first time to be infecting humans. Until now the virus was noted to infect only animals.

22 Jun 2018

FDA approves Eversense CGM system for use in adults with diabetes

The U.S. Food and Drug Administration today approved the Eversense Continuous Glucose Monitoring (CGM) system for use in people 18 years of age and older with diabetes.

21 Jun 2018