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New RNA sequencing method improves rare disease diagnosis

Researchers from Children's Hospital of Philadelphia (CHOP) developed a new RNA sequencing strategy that can reveal how genetic variants disrupt gene function and improve the diagnosis of rare diseases.

15 Apr 2026

Matching exercise timing to body clock chronotype improves heart health

Timing exercise to match body clock chronotype-the natural predisposition to morning or evening alertness-may lower cardiovascular disease risk among those who are already vulnerable, suggests research published in the open access journal Open Heart.

15 Apr 2026

Semaglutide improves liver function independently of weight loss

Researchers at Toronto's Sinai Health have found that semaglutide – the active ingredient in popular weight loss drugs that mimic the gut hormone GLP-1 – acts directly on a subset of liver cells to improve organ function and does so independently of weight loss.

15 Apr 2026

Brain organoids reveal mutation-specific insights for Rett syndrome

Though many studies approach the developmental disorder Rett syndrome as a single condition arising from general loss of function in the gene MECP2, a new study by neuroscientists in The Picower Institute for Learning and Memory at MIT shows that two different mutations of the gene caused many distinct abnormalities in lab cultures.

15 Apr 2026

Brief intense workouts offer significant health benefits

At this time of year, many people make an extra effort to establish good exercise routines. We know that exercise is good for our health, but it can still be difficult to get started and maintain good habits.

15 Apr 2026

New biochip detects tiny genetic markers in 20 minutes

A team of scientists from Nanyang Technological University, Singapore (NTU Singapore) has developed a new biochip that, when paired with Artificial Intelligence (AI), can detect quickly and accurately extremely small amounts of microRNAs, which are tiny genetic markers linked to diseases such as heart disease.

15 Apr 2026

Breakthrough blood test predicts kidney failure years before clinical symptoms

A new blood test can identify which individuals of African ancestry carrying high-risk APOL1 gene variants are most likely to develop kidney failure, years before clinical disease becomes apparent.

15 Apr 2026

Loneliness is linked to higher risk of degenerative heart valve disease

Adults who reported feeling lonely had a higher risk of developing degenerative heart valve disease, even after accounting for traditional heart disease risk factors and genetics, according to new research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

15 Apr 2026

Rural Nebraska dialysis unit closes despite the state’s $219M in rural health funding

The sun was just warming the horizon as Mark Pieper left his house near his cattle ranch on a crisp February morning.

15 Apr 2026

Metabolic syndrome doubles worldwide over two decades

A global study reveals a sharp rise in metabolic syndrome prevalence from 2000 to 2023, highlighting urgent public health challenges and regional disparities.

15 Apr 2026

Waist-to-height ratio outperforms BMI in predicting hypertension risk

New waist-to-height cut-offs to assess fat mass and obesity predicted the risk of hypertension better than body mass index, according to a new study from the University of Eastern Finland and the Robert Wood Johnson Medical School at Rutgers University in the US.

14 Apr 2026

Experimental drug shows survival benefit in pancreatic cancer trial

Pancreatic cancer is one of the deadliest cancers and among the hardest to treat, with most patients surviving less than a year after diagnosis.

14 Apr 2026

Study identifies new genes linked to severe pregnancy sickness

The USC research team that recently identified the hormone-encoding gene GDF15 as a key driver of pregnancy sickness has identified 9 additional genes linked to its most severe form, hyperemesis gravidarum (HG).

14 Apr 2026

Study finds long COVID leaves a distinct immune signature in the blood

Researchers identified a small panel of inflammatory and neurology-related blood proteins that may help distinguish long COVID from recovery or no prior infection, while also showing that booster vaccination did not appear to worsen these protein responses in this cohort. The study also found that immune responses after reinfection differed from those seen after the first SARS-CoV-2 infection, suggesting altered long-term immune behavior in some previously infected individuals.

14 Apr 2026

Feeling lonely impacts memory without accelerating mental decline

Loneliness affects the memory of older adults but does not speed up mental decline over time, suggests data from a major European study tracking more than 10,000 people over seven years.

14 Apr 2026

Common osteoporosis drugs could slow or halt aneurysm progression

Aortic aneurysms are characterized by abnormal enlargement of the aorta, the primary artery responsible for carrying blood from the heart. Rupture often leads to sudden death, and currently, no effective drug therapies are available to halt disease progression.

14 Apr 2026

Microplastics lab studies may fail to reflect real-world exposure

Microplastics pose health risks, but lab studies often fail to reflect real-world exposure, highlighting critical gaps in toxicological research methodologies.

14 Apr 2026

Prostate cancer patients recover faster with TULSA than robotic surgery

A new randomized clinical trial found that men with localized, intermediate‑risk prostate cancer recovered faster and experienced less short‑term impact on their daily lives when treated with MRI‑guided, transurethral ultrasound ablation (TULSA) compared with robotic prostate surgery.

13 Apr 2026

Beetroot supplement raises nitric oxide markers in triathletes after one week

A randomized cross-over pilot study in 10 amateur male triathletes found that a beetroot-based multi-ingredient nitrate supplement increased nitric oxide-related and redox biomarkers over 7 days without evidence of lipid oxidative damage. The supplement was generally well tolerated, but the study did not measure whether these biochemical changes improved performance or recovery.

13 Apr 2026

Study shows why an apple a day may work differently for different people

A 12-week single-blind trial in 38 Japanese adults found that daily Fuji apple intake did not significantly change overall host metabolic markers, but responses differed by baseline gut enterotype. Participants in the Bacteroidaceae-dominant enterotype showed significant increases in fecal short-chain fatty acids after apple consumption, suggesting that gut microbiota structure may shape functional dietary responses.

13 Apr 2026