Genes News and Research

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HDAC inhibitors may help regulate alcoholism-induced anxiety

Epigenetics is the study of changes in organisms caused by modifying gene expression - by alcohol, for example - rather than alteration of the genetic code itself. Recent evidence suggests that alcohol can inhibit activity of an enzyme called histone deacetylase (HDAC) in the amygdala, a brain region that is crucial for storing memories and regulating fear, anxiety, and other emotions.

27 Jun 2016

Eye donations: what stops people? An interview with Rory Passmore

Despite a shortage of corneas for transplant purposes, our new research reveals that eyes are the one body part we are least likely to donate.

27 Jun 2016

Scientists discover link between two genes involved in PD and autoimmune diseases

A study publish in the journal CELL indicates that two genes associated with Parkinson's disease (PD) are key regulators of the immune system, providing direct evidence linking Parkinson's to autoimmune disease.

27 Jun 2016

Oncogene signatures could help design new drug treatments for breast cancer

Drug treatments for breast cancer patients might soon be designed based on the unique genetic autograph of their tumor.

25 Jun 2016

Study reveals distribution of toxic arsenic in cell nuclei of plants

Toxic arsenic initially accumulates in the nuclei of plants' cells. This has been revealed by an X-ray examination of the aquatic plant rigid hornwort (Ceratophyllum demersum) using DESY's X-ray source PETRA III.

25 Jun 2016

Researchers tune into previously unknown cross talk between estrogen and progesterone receptors

One of the first clues pathologists look for in tissue from a newly diagnosed breast cancer patient is the estrogen receptor, a nuclear protein that converts hormonal messages in the bloodstream into instructions for the cell about how to behave

24 Jun 2016

New study shows microRNAs play important role in inducing asthma

A new study shows that microRNAs, which are small, noncoding RNA molecules that can silence genes, have an important role in inducing asthma.

24 Jun 2016

Scientists insert metabolic pathway for carbon fixation and sugar production into E. coli bacterium

All life on the planet relies, in one way or another, on a process called carbon fixation: the ability of plants, algae and certain bacteria to "pump" carbon dioxide (CO2) from the environment, add solar or other energy and turn it into the sugars that are the required starting point needed for life processes.

24 Jun 2016

HMC signal could be used to detect diseases and to personalize medication

Common diseases like allergy, diabetes and other immune diseases have increased dramatically in recent decades. This indicates that the environment may have a more important role than genes in explaining this increase.

24 Jun 2016

Mutant fruit flies provide insight into origins of Parkinson's disease

The neurodegeneration that occurs in Parkinson’s disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought, according to a study in fruit flies.

24 Jun 2016

Scientists uncover how changes in metabolism of embryonic stem cells can help engineer new blood vessels

Researchers from the University of Illinois at Chicago College of Medicine have uncovered how changes in metabolism of human embryonic stem cells help coax them to mature into specific cell types — and may improve their function in engineered organs or tissues.

24 Jun 2016

Scientists elucidate why acute leukemias with same genetic abnormality vary in aggressiveness

Scientists at the Friedrich Miescher Institute for Biomedical Research and the University of Basel have discovered why acute leukemias with the same genetic abnormality vary in their aggressiveness based on their cellular origin.

24 Jun 2016

Researchers identify new potential target for pancreatic cancer treatment

Using an innovative approach to identify a cancer's genetic vulnerabilities by more swiftly analyzing human tumors transplanted into mice, researchers have identified a new potential target for pancreatic cancer treatment, published online in Cell Reports.

24 Jun 2016

Positive environment can reverse trauma-related behavioral alterations in mice

Traumatic experiences in childhood increase the risk of developing behavioral and psychiatric disorders later in life. It is also known that the consequences of a trauma can likewise be observed in the children of people affected even if those children have themselves not experienced any trauma.

24 Jun 2016

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Potent doses of broccoli sprout extract activate a "detoxification" gene and may help prevent cancer recurrence in survivors of head and neck cancer, according to a trial by the University of Pittsburgh Cancer Institute, partner with UPMC CancerCenter, confirming preliminary results presented last year at the American Association for Cancer Research Annual Meeting.

24 Jun 2016

Yale-led study shows how EGFR silences tumor suppressor genes

A Yale-led study describes how a known cancer gene, EGFR, silences genes that typically suppress tumors. The finding, published in Cell Reports, may lead to the development of more effective, individualized treatment for patients with lung cancer and other cancer types.

24 Jun 2016

Scientists discover how faulty genetic instructions contribute to development of AML

Scientists have previously identified a series of genetic errors that commonly occur inside cancerous blood cells, but it hasn't been clear exactly how those genetic malfunctions create immature blood cells that overpopulate, crowd out healthy cells and spread in patients with acute myeloid leukemia or AML.

24 Jun 2016

Researchers use sensitive technique to reveal high levels of genetic heterogeneity in schizophrenia

International researchers centered at Nagoya University use a highly sensitive technique to identify significantly more DNA sequence repeats in patients with schizophrenia than in control individuals, and outline a possible link between genome instability and disease.

24 Jun 2016

Study reveals surprising diversity in single neuronal transcriptomes of the brain

A team of scientists at The Scripps Research Institute, University of California, San Diego and Illumina, Inc., has completed the first large-scale assessment of single neuronal "transcriptomes."

24 Jun 2016

University of Miami researchers awarded new contracts to detect genetic factors linked to Alzheimer's disease risk

Alzheimer's disease is the leading cause of dementia in the elderly and occurs in all ethnic and racial groups. It affects more than 5 million people age 65 and older in the United States alone and there is currently no effective treatment or cure.

24 Jun 2016

Genes News and Research

HDAC inhibitors may help regulate alcoholism-induced anxiety

Eye donations: what stops people? An interview with Rory Passmore

Scientists discover link between two genes involved in PD and autoimmune diseases

Oncogene signatures could help design new drug treatments for breast cancer

Study reveals distribution of toxic arsenic in cell nuclei of plants

Researchers tune into previously unknown cross talk between estrogen and progesterone receptors

New study shows microRNAs play important role in inducing asthma

Scientists insert metabolic pathway for carbon fixation and sugar production into E. coli bacterium

HMC signal could be used to detect diseases and to personalize medication

Mutant fruit flies provide insight into origins of Parkinson's disease

Scientists uncover how changes in metabolism of embryonic stem cells can help engineer new blood vessels

Scientists elucidate why acute leukemias with same genetic abnormality vary in aggressiveness

Researchers identify new potential target for pancreatic cancer treatment

Positive environment can reverse trauma-related behavioral alterations in mice

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Yale-led study shows how EGFR silences tumor suppressor genes

Scientists discover how faulty genetic instructions contribute to development of AML

Researchers use sensitive technique to reveal high levels of genetic heterogeneity in schizophrenia

Study reveals surprising diversity in single neuronal transcriptomes of the brain

University of Miami researchers awarded new contracts to detect genetic factors linked to Alzheimer's disease risk

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