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Penn researchers generate functional CAR T cells with enhanced anti-tumor potency in 24 hours

A new approach from Penn Medicine researchers could cut the time it takes to alter patients' immune cells for infusion back into the body to find and attack cancer.

29 Mar 2022

Good hydration may be linked with reduced risk of heart failure

Staying well-hydrated may be associated with a reduced risk for developing heart failure, according to researchers at the National Institutes of Health.

29 Mar 2022

Study finds less diverse circulating antibodies in aging killifish

As we age, our immune system works less well. We become more susceptible to infections and vaccinations no longer work as effectively.

29 Mar 2022

Study shows potential inhibition of SARS-CoV-2 main protease by natural phytochemicals

A new study assessed the molecular dynamics of potentially active natural phytochemicals to target the SARS-CoV-2 main protease.

29 Mar 2022

Study reveals a deeper level of cellular heterogeneity within fallopian tubes

The fallopian tube is the site of fertilization, where once a month for the duration of a female's post-pubescent, pre-menopausal life, an egg is moved from the ovary, ready for fertilization by a sperm cell.

29 Mar 2022

Characterization of the different expressed RNAseq variants in SARS-CoV-2 infected patients

A recent study analyzed the RNAseq variants of COVID-19 patients and healthy donors.

29 Mar 2022

Immune response dynamics following COVID-19 heterologous and homologous vaccinations

Researchers evaluated the cellular and humoral immunity following heterologous and homologous COVID-19 immunization regimens for up to five months.

29 Mar 2022

Is SARS-CoV-2 a Superantigen?

Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), scientists have been conducting extensive studies to understand various aspects of the virus. Researchers have stated that SARS-CoV-2 manifests several biological and clinical consequences of a superantigen

29 Mar 2022

Genetic risk for asthma may be mediated through altered gene expression in the airway cells

A significant amount of genetic risk for asthma is likely mediated through altered gene expression within the airway epithelium.

28 Mar 2022

One year after severe COVID-19, T cells persist against SARS-CoV-2

In a recently published article in the journal eBioMedicine, scientists have demonstrated that critically ill coronavirus disease 2019 (COVID-19) patients are capable of generating durable memory T cell response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for more than one year after hospital discharge.

28 Mar 2022

Study provides insights on how risk factors following ICH stroke can affect patient outcomes

A new study led by University of Cincinnati researchers provides new insights on how different risk factors following one of the most severe types of stroke can affect patient outcomes.

28 Mar 2022

Northwestern scientists continue to advance the understanding of COVID-19

As the COVID-19 pandemic enters its third year, Northwestern Medicine scientists continue to help advance the understanding of the disease and its impact, from investigating antibody protection against COVID-19 reinfection to elevating women in academic research and highlighting racial and ethnic disparities in COVID-19 hospital mortality in Illinois.

28 Mar 2022

Natural SARS-CoV-2 antibodies persist for six months in children

Researchers investigate the presence of antibodies against SARS-CoV-2 in children between the ages of five and 19 after infection.

28 Mar 2022

New technology could replace conventional biopsies and histology with real-time imaging

MediSCAPE, a high-speed 3D microscope designed by Columbia Engineers, can see real-time cellular detail in living tissues to guide surgery, speed up tissue analyses, and improve treatments.

28 Mar 2022

Deleting a protein could prevent heart attacks and strokes in humans

Macrophages travel through our arteries, gobbling fat the way Pac-man gobbled ghosts. But fat-filled macrophages can narrow blood vessels and cause heart disease.

28 Mar 2022

Magneto-activated natural killer cells for treating solid tumors

Cancer immunotherapy - a type of treatment that enlists our own immune cells to attack tumors - has revolutionized the way that many types of cancer are treated. One type of immunotherapy under investigation uses natural killer cells, a type of immune cell that can seek and destroy harmful cells.

28 Mar 2022

Timely stroke treatment could benefit people with preexisting disability and dementia

According to a new American Heart Association scientific statement, people with dementia or a pre-existing disability who receive timely and appropriate treatment for ischemic stroke (caused by a blood clot) may avoid additional disability and the subsequent health and financial impacts of stroke.

28 Mar 2022

Chaperone-mediated autophagy needed to protect against atherosclerosis

Revving up a process that slows down as we age may protect against atherosclerosis, a major cause of heart attacks and strokes.

28 Mar 2022

New, potential treatment combination for patients with aggressive head and neck cancer

The current treatment of patients diagnosed with advanced or metastatic head and neck cancer (HNC) is ineffective.

28 Mar 2022

Depression occurs independently of inflammation for many older people, study suggests

Multiple prior studies have found higher levels of inflammation in older individuals with depression. Now, a new Penn Medicine study has found that clinically depressed older individuals, on average, don't have elevated levels of inflammation if they don't already have other inflammatory conditions such as arthritis.

28 Mar 2022

Blood News and Research

Penn researchers generate functional CAR T cells with enhanced anti-tumor potency in 24 hours

Good hydration may be linked with reduced risk of heart failure

Study finds less diverse circulating antibodies in aging killifish

Study shows potential inhibition of SARS-CoV-2 main protease by natural phytochemicals

Study reveals a deeper level of cellular heterogeneity within fallopian tubes

Characterization of the different expressed RNAseq variants in SARS-CoV-2 infected patients

Immune response dynamics following COVID-19 heterologous and homologous vaccinations

Is SARS-CoV-2 a Superantigen?

Genetic risk for asthma may be mediated through altered gene expression in the airway cells

One year after severe COVID-19, T cells persist against SARS-CoV-2

Study provides insights on how risk factors following ICH stroke can affect patient outcomes

Northwestern scientists continue to advance the understanding of COVID-19

Natural SARS-CoV-2 antibodies persist for six months in children

New technology could replace conventional biopsies and histology with real-time imaging

Deleting a protein could prevent heart attacks and strokes in humans

Magneto-activated natural killer cells for treating solid tumors

Timely stroke treatment could benefit people with preexisting disability and dementia

Chaperone-mediated autophagy needed to protect against atherosclerosis

New, potential treatment combination for patients with aggressive head and neck cancer

Depression occurs independently of inflammation for many older people, study suggests

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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