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Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

Low levels of BPA exposure may be considered safe, but new research published online in The FASEB Journal, suggests otherwise. In the report, researchers from Yale show that the genome is permanently altered in the uterus of mice that had been exposed to BPA during their fetal development.

17 Jun 2016

Scientists identify potential drug target that disrupts Zika and similar viruses

Scientists potentially have found a way to disrupt Zika and similar viruses from spreading in the body.

17 Jun 2016

Study provides valuable insight into biology of tumours in early stages of cancer

Bladder cancer is a frequent disease affecting approximately 1,900 persons in Denmark annually. A high number of these patients only have superficial tumours in the bladder when the disease is diagnosed.

17 Jun 2016

Review sheds light on current therapeutic targets of miRNA-associated chemoresistance in EOC

Epithelial ovarian cancer (EOC) is the most lethal disease among gynecologic malignancies. Patients with an advanced disease often relapse due to the development of chemoresistance. Chemotherapy failure is a consequence of acquired drug resistance which may potentially be due to multiple mechanisms including miRNA-mediated gene regulation.

17 Jun 2016

Cells grown from pluripotent stem cells can pair with heart muscle cells to stimulate contractions

Researchers at Johns Hopkins report that a type of lab-grown human nerve cells can partner with heart muscle cells to stimulate contractions.

17 Jun 2016

RVFV uses cancer pathway to hijack host cell and cause infection

Viruses can't live without us -- literally. As obligate parasites, viruses need a host cell to survive and grow. Scientists are exploiting this characteristic by developing therapeutics that close off pathways necessary for viral infection, essentially stopping pathogens in their tracks.

17 Jun 2016

Knocking out genes in E. coli affects stiffness, integrity of bacterial envelope

An exhaustive look at how bacteria hold their ground and avoid getting pushed around by their environment shows how dozens of genes aid the essential job of protecting cells from popping when tensions run high.

17 Jun 2016

New research helps better understand role of TIP60 in allowing tumors to survive in low-oxygen environments

In summer 2011, University of Colorado Cancer Center investigators Joaquín Espinosa, PhD, and Matthew Galbraith, PhD, taught a summer symposium on gene expression at Cold Spring Harbor Laboratory in Long Island, New York.

17 Jun 2016

Mother's obesity can impair health of future generations

New research suggests that mothers who eat high-fat, high-sugar diets can predispose multiple generations to metabolic problems, even if their offspring consume healthy diets.

17 Jun 2016

Mice study highlights vital role of liver in balancing fats and sugars

Sugar in the form of blood glucose provides essential energy for cells. When its usual dietary source — carbohydrates — is scarce, the liver can produce it with the aid of fat.

17 Jun 2016

Tumour protein TP53 can locate DNA targets autonomously to prevent cancer

Geneticists from KU Leuven, Belgium, have shown that tumour protein TP53 knows exactly where to bind to our DNA to prevent cancer. Once bound to this specific DNA sequence, the protein can activate the right genes to repair damaged cells.

17 Jun 2016

Scientists develop new software program that can help compare large amounts of metagenomes

Scientists from ITMO University, the Federal Research and Clinical Centre of Physical-Chemical Medicine and MIPT have developed a software program enabling them to quickly compare sets of DNA of microorganisms living in different environments. The researchers have already suggested exactly how the new program could be applied in practice.

16 Jun 2016

Researchers highlight gene loss as potential process of genetic change, evolutionary adaption

"Loss is nothing else but change and change is nature's delight" says the quote by the philosopher and emperor Marcus Aurelius, which opens the scientific article that analyses the gene loss phenomenon and its impact on the evolution of living beings.

16 Jun 2016

Research suggests gonad as vital player in evolutionary process

A pair of studies led by Indiana University researchers provide new evidence that when it comes to evolution, the testes may play a key role.

16 Jun 2016

New research paves way for potential notch-based anticancer therapeutics

A recent study led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, in collaboration with the Univerity of Maryland School of Pharmacy and StemSynergy Therapeutics, Inc., has identified a small-molecule inhibitor of the Notch pathway, paving the way for a potential new class of personalized cancer medicines.

16 Jun 2016

Penn researchers help identify unique characteristics of reserve stem cells

Adult stem cells represent a sort of blank clay from which a myriad of different cell and tissue types are molded and as such are of critical importance to health, aging and disease.

16 Jun 2016

MicroRNA plays role in blocking development of arterial thrombosis

The dangers of arterial thrombosis - the formation of blood clots that can block arteries and cause illness or death - can escalate through a vicious cycle of coagulation and inflammation.

15 Jun 2016

New and inexpensive technique could help meet global demands for malaria drug

A new and inexpensive technique for mass-producing the main ingredient in the most effective treatment for malaria, artemisinin, could help meet global demands for the drug, according to a study to be published in the journal eLife.

15 Jun 2016

QIAGEN announces launch of QIAsure Methylation Test to detect cervical cancer risk

QIAGEN N.V. today announced the launch of the QIAsure Methylation Test, a novel CE-marked molecular diagnostic test for use in differentiating patients' risk of developing cervical cancer.

From QIAGEN Manchester Limited 15 Jun 2016

Scientists aim to heal failing heart with the body’s own cells

Babies born with heart defects live longer than ever thanks to advances in the diagnosis and treatment of congenital heart disease. Yet, despite substantial progress, many continue to face bleak odds, lifelong medication, multiple surgeries and progressive heart failure, often requiring a transplant.

15 Jun 2016

Genes News and Research

Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

Scientists identify potential drug target that disrupts Zika and similar viruses

Study provides valuable insight into biology of tumours in early stages of cancer

Review sheds light on current therapeutic targets of miRNA-associated chemoresistance in EOC

Cells grown from pluripotent stem cells can pair with heart muscle cells to stimulate contractions

RVFV uses cancer pathway to hijack host cell and cause infection

Knocking out genes in E. coli affects stiffness, integrity of bacterial envelope

New research helps better understand role of TIP60 in allowing tumors to survive in low-oxygen environments

Mother's obesity can impair health of future generations

Mice study highlights vital role of liver in balancing fats and sugars

Tumour protein TP53 can locate DNA targets autonomously to prevent cancer

Scientists develop new software program that can help compare large amounts of metagenomes

Researchers highlight gene loss as potential process of genetic change, evolutionary adaption

Research suggests gonad as vital player in evolutionary process

New research paves way for potential notch-based anticancer therapeutics

Penn researchers help identify unique characteristics of reserve stem cells

MicroRNA plays role in blocking development of arterial thrombosis

New and inexpensive technique could help meet global demands for malaria drug

QIAGEN announces launch of QIAsure Methylation Test to detect cervical cancer risk

Scientists aim to heal failing heart with the body’s own cells

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