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Novel nanoparticle therapeutics shows promise to fight solid tumors

Researchers from Wake Forest University School of Medicine have discovered a possible new approach to treating solid tumors through the creation of a novel nanoparticle. Solid tumors are found in cancers such as breast, head and neck, and colon cancer.

14 Jun 2022

Temple researcher receives NIH award to study the link between HIV, substance use and heart disease

With prompt diagnosis and the right treatment, people with HIV can live long, healthy lives. In recent years, however, gains in survival among people with HIV have exposed a new concern – an increase in the incidence of early-onset cardiovascular disease associated with long-term HIV.

14 Jun 2022

New protocol can develop safe, efficient pluripotent stem cell-based therapies for macular degeneration

As we age, so do our eyes; most commonly, this involves changes to our vision and new glasses, but there are more severe forms of age-related eye problems.

14 Jun 2022

New potato processing technique slows starch digestion to avoid blood sugar spikes

Researchers announced early tests of a new potato processing technique designed to make our bodies digest potato starch more slowly.

14 Jun 2022

Increasing growth hormone levels can improve liver health in patients with NAFLD

Growth hormone improves liver health in patients with nonalcoholic fatty liver disease (NAFLD) by reducing liver fat and inflammation, according to a new study presented Tuesday, June 14 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

14 Jun 2022

Researchers discover specific genetic signals in people who develop severe COVID-19

Researchers from the University of Sheffield and Stanford University in the US have discovered there are specific genetic signals in people who develop severe coronavirus infection.

14 Jun 2022

seqWell appoints Dr Amy Liao to Board of Directors

seqWell, a global provider of genomic library workflow solutions including the plexWell™ next-generation sequencing (NGS) multiplexing technology, today announced the appointment of Dr Amy Liao to its Board.

From seqWell 14 Jun 2022

Spirea raises £2.4M ($3M) to develop antibody drug conjugates in cancer

Funding will enable the development of Spirea’s pipeline of antibody drug conjugate therapeutics for the treatment of solid tumours.

From Spirea 14 Jun 2022

The potential mechanisms of SARS-CoV-2 to induce DNA damage

Researchers described potential mechanisms of coronaviruses that could lead to DNA damage and the potential link between SARS-CoV-2 activity and such mechanisms.

14 Jun 2022

The role of ARF6 in SARS-CoV-2 endocytosis and infection

Researchers assessed the role of adenoside diphosphate (ADP)-ribosylation factor 6 (ARF6) in SARS-CoV-2 infection.

14 Jun 2022

Molecular snapshots of the productive infectious entry pathway of SARS-CoV-2 into cells

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States demonstrated that the acidic milieu of the nasal cavity is critical for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) tropism.

14 Jun 2022

Elevated Th17 cells associated with increased risk of critical COVID

In a recent article published in the European Journal of Internal Medicine, researchers in France indicated that T cell immune reaction correlates possibly with the chance of critical severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among hospitalized patients.

14 Jun 2022

Orbit Discovery awarded Innovate UK grant to expand high throughput cell-based functional screening platform capabilities in peptide drug discovery

Orbit Discovery Ltd., (“Orbit”) a privately held biopharmaceutical company focused on discovering candidate peptide therapeutics harnessing proprietary affinity and cell-based functional screening platforms, has been awarded a Smart grant by Innovate UK, the UK’s innovation agency.

From Orbit Discovery 14 Jun 2022

New approach to quantify tumor-specific total mRNA levels from patient tumor samples

Researchers at The University of Texas MD Anderson Cancer Center have developed a new approach to quantify tumor-specific total mRNA levels from patient tumor samples, which contain both cancer and non-cancer cells.

14 Jun 2022

The microbiome plays a vital role in a healthy diet

A recent study discusses the current national nutritional recommendations from the viewpoint of the gut microbiota.

14 Jun 2022

The severity of COVID-19 compared to seasonal influenza

In a recent study under review at the Archives of Virology journal and currently posted to the Research Square* preprint server, investigators in Israel assessed the disparities and similarities between seasonal influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

14 Jun 2022

Genomic analysis of the 2022 monkeypox outbreak

In a recent study posted to the bioRxiv* pre-print server, researchers analyzed two genomic sequences of the Monkeypox virus from Belgium and Portugal termed ITM001 and PT0001, respectively, to show that the May 2022 Monkeypox outbreak most likely originated from the West African clade of the virus.

14 Jun 2022

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

Researchers from the Department of Pathology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) have identified a new metabolic mechanism in liver cancer cells, by which macropinocytosis, an endocytic process, is used to engulf extracellular proteins as fuels to support the unlimited growth of hepatocellular carcinoma (HCC) in hypoxia (oxygen deprivation).

14 Jun 2022

New project seeks to develop a microscopy system for making drug interactions in the liver visible

Bielefeld University is coordinating a new EU-research project that seeks to produce microscopic liver tissue cultures that can survive for 14 days, while also using imaging methods to investigate how liver cells react to combinations of different medications.

14 Jun 2022

OSU researchers study quorum sensing in a gram-negative bacterium that displays social behaviors

Oregon State University scientists have identified proteins that prevent a bacterial cell from becoming misguided by its own messaging, allowing it to instead wait for collective communication from its group.

13 Jun 2022

Cell News and Research

Novel nanoparticle therapeutics shows promise to fight solid tumors

Temple researcher receives NIH award to study the link between HIV, substance use and heart disease

New protocol can develop safe, efficient pluripotent stem cell-based therapies for macular degeneration

New potato processing technique slows starch digestion to avoid blood sugar spikes

Increasing growth hormone levels can improve liver health in patients with NAFLD

Researchers discover specific genetic signals in people who develop severe COVID-19

seqWell appoints Dr Amy Liao to Board of Directors

Spirea raises £2.4M ($3M) to develop antibody drug conjugates in cancer

The potential mechanisms of SARS-CoV-2 to induce DNA damage

The role of ARF6 in SARS-CoV-2 endocytosis and infection

Molecular snapshots of the productive infectious entry pathway of SARS-CoV-2 into cells

Elevated Th17 cells associated with increased risk of critical COVID

Orbit Discovery awarded Innovate UK grant to expand high throughput cell-based functional screening platform capabilities in peptide drug discovery

New approach to quantify tumor-specific total mRNA levels from patient tumor samples

The microbiome plays a vital role in a healthy diet

The severity of COVID-19 compared to seasonal influenza

Genomic analysis of the 2022 monkeypox outbreak

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

New project seeks to develop a microscopy system for making drug interactions in the liver visible

OSU researchers study quorum sensing in a gram-negative bacterium that displays social behaviors

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