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Click-like chemistry enables rapid development of LNPs for enhanced mRNA delivery

Imagine a scenario where a skilled hacker must upload critical software to update a central server and thwart a potentially lethal virus from wreaking havoc across a vast computer network.

10 Jul 2024

Scientists identify over 5,000 genetic variants that enable certain cancers to thrive

Researchers performed saturation genome editing of the BAP1, whose dysfunction is related to cancer and impaired neurodevelopment.

10 Jul 2024

Pregnancy loss risk heightened by family history of endocrine diseases

Women who have close family members with endocrine diseases, including type 2 diabetes, thyroid diseases and polycystic ovary syndrome (PCOS), are at higher risk of pregnancy loss, a new study has found.

9 Jul 2024

COVID-19 and metallic taste: Study connects immunoglobulin levels to sensory impairment

Researchers investigated whether COVID-19-related sensory deficiencies are associated with transcriptome changes in the foliate papillae area of the tongue.

9 Jul 2024

How does SARS-CoV-2 cause lymphopenia when T cells barely express ACE-2 receptors?

Researchers reveal both direct and indirect mechanisms of SARS-CoV-2-induced lymphopenia, highlighting the role of CD147 and alternative viral entry routes into T cells.

8 Jul 2024

Blocking IL-6 in the brain to treat cancer cachexia

Cancer is insidious. Throughout tumor progression, the disease hijacks otherwise healthy biological processes - like the body's immune response - to grow and spread.

8 Jul 2024

Case Western Reserve University receives $1.5M grant for oral drug trial to prevent blindness in RP patients

There's only one U.S. Food and Drug Administration-approved therapy for an inherited retinal disease, and dozens of retinitis pigmentosa (RP) genes for which no therapy is available.

8 Jul 2024

First-in-class oral drug improves embryo implantation and pregnancy outcomes in IVF

New research has demonstrated the effectiveness of a first-in-class oral, non-hormonal drug in increasing embryo implantation, pregnancy and live birth rates among infertile women who are undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI).

8 Jul 2024

Small molecule discovery offers hope for treatment of Angelman syndrome

Angelman syndrome is a rare genetic disorder caused by mutations in the maternally-inherited UBE3A gene and characterized by poor muscle control, limited speech, epilepsy, and intellectual disabilities.

8 Jul 2024

COVID-19 vaccination linked to reduced symptomatic child asthma

Researchers found that higher COVID-19 vaccination rates are linked to reduced asthma symptoms in children, highlighting broader health benefits of vaccination during the pandemic.

8 Jul 2024

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Researchers discovered that interferon-stimulated SAMD9L restricts HIV-1 and other lentiviruses by inhibiting viral translation and endosomal trafficking, while SAMD9 enhances HIV-1 replication.

7 Jul 2024

PCOS linked to higher risk of adverse birth outcomes

The association between polycystic ovary syndrome (PCOS) and birth outcomes in women.

5 Jul 2024

Enhancing heart failure management with cardiac magnetic resonance imaging

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Heart failure (HF) is a clinical syndrome with a wide variety of clinical presentations, pathophysiologies, and natural histories.

4 Jul 2024

In-hospital delirium linked to long-term cognitive impairment in COVID-19 patients over 60

The association of in-hospital delirium with functional disability and cognitive impairment.

4 Jul 2024

Beyond PMS: A poorly understood disorder means periods of despair for some women

For the most part, Cori Lint was happy. She worked days as a software engineer and nights as a part-time cellist, filling her free hours with inline skating and gardening and long talks with friends.

3 Jul 2024

Gene mutation explains heart defects in children

A new groundbreaking study sheds light on a medical question scientists have long wondered: why do 40 per cent of children with the rare neurodevelopmental disorder KBG syndrome have heart defects? The research now points to a critical link between the heart and the brain.

3 Jul 2024

Frequent infections and pathobionts boost children's nasal immunity, study reveals

Dynamic interactions with viruses and bacterial pathobionts significantly enhance nasal innate immunity in children, revealing distinct immunophenotypes driven by microbial load and type.

2 Jul 2024

Study reveals refined carbs heighten inflammation and cardiovascular risk

A study in Nutrients journal finds that both the quantity and quality of carbohydrates impact inflammation and cardiovascular disease (CVD) risk. Higher refined carbohydrate intake is linked to greater inflammation and CVD, emphasizing the need for personalized dietary recommendations.

2 Jul 2024

Sedentary lifestyle and screen time linked to rising metabolic syndrome in Chinese youth

A new study reveals that sedentary behavior and increased screen time significantly contribute to the prevalence of metabolic syndrome (MetS) among Chinese children and adolescents, with 5.5% affected. Urban living, older age, and higher sedentary time increase the risk of MetS.

2 Jul 2024

Implementing patient-centered palliative care may help improve quality of life for people with heart disease

Implementing patient-centered palliative care therapies, including prescribing, adjusting or discontinuing medications as needed, may help control symptoms and improve quality of life for people with heart disease, according to "Palliative Pharmacotherapy for Cardiovascular Disease," a new scientific statement from the American Heart Association, published today in the Association's journal, Circulation: Cardiovascular Quality and Outcomes.

1 Jul 2024

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Syndrome News and Research

Click-like chemistry enables rapid development of LNPs for enhanced mRNA delivery

Scientists identify over 5,000 genetic variants that enable certain cancers to thrive

Pregnancy loss risk heightened by family history of endocrine diseases

COVID-19 and metallic taste: Study connects immunoglobulin levels to sensory impairment

How does SARS-CoV-2 cause lymphopenia when T cells barely express ACE-2 receptors?

Blocking IL-6 in the brain to treat cancer cachexia

Case Western Reserve University receives $1.5M grant for oral drug trial to prevent blindness in RP patients

First-in-class oral drug improves embryo implantation and pregnancy outcomes in IVF

Small molecule discovery offers hope for treatment of Angelman syndrome

COVID-19 vaccination linked to reduced symptomatic child asthma

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

PCOS linked to higher risk of adverse birth outcomes

Enhancing heart failure management with cardiac magnetic resonance imaging

In-hospital delirium linked to long-term cognitive impairment in COVID-19 patients over 60

Beyond PMS: A poorly understood disorder means periods of despair for some women

Gene mutation explains heart defects in children

Frequent infections and pathobionts boost children's nasal immunity, study reveals

Study reveals refined carbs heighten inflammation and cardiovascular risk

Sedentary lifestyle and screen time linked to rising metabolic syndrome in Chinese youth

Implementing patient-centered palliative care may help improve quality of life for people with heart disease

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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