Genes News and Research

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Study provides better understanding of sequence of genetic events in colorectal cancer premalignancy

Whole-exome sequencing of both colorectal adenomas (precancers often called polyps) and intestinal mucosa at risk for developing into adenomas from patients with familial adenomatous polyposis (FAP) has generated a comprehensive picture of the genomic alterations that characterize the evolution of normal mucosa to precancer.

25 May 2016

Sylvester researchers test new KTE-C19 therapy for patients with aggressive non-Hodgkin's lymphoma

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine are testing a novel cellular immunotherapy approach to treating patients with diffuse large B-cell lymphoma who have failed standard therapy.

25 May 2016

Technical advances in neuroimaging offer new promise to clinicians

The current special issue of Technology and Innovation, Journal of the National Academy of Inventors, Volume 18, Number 1 (all open access), is devoted to the evolution of neuroimaging technology, with seven articles chronicling the latest advances in this critical area.

25 May 2016

ANK3 and other genes may play key role in affecting mood, stress and longevity

The visible impacts of depression and stress that can be seen in a person's face -- and contribute to shorter lives -- can also be found in alterations in genetic activity, according to newly published research.

24 May 2016

Scientists study how viral evolution occurs

Viruses evolve quickly. A small tweak to the genetic makeup of a mostly mild strain of influenza can give rise to the next pandemic. An equally small change to the same strain in a different setting can fade it into obscurity.

24 May 2016

Vitamin D and androgen receptor-targeted therapy may help treat TNBC

A recent study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine revealed that triple-negative breast cancer (TNBC), which has generally been unresponsive to hormone receptor-targeted treatments, can indeed be treated using vitamin D and androgen receptor-targeted therapy.

24 May 2016

Researchers find genetic mutations linked to increased risk factor for PTSD

In the largest study of DNA samples from service members with Post-Traumatic Stress Disorder (PTSD), researchers have identified genetic mutations that may be associated with an increased risk factor for PTSD.

24 May 2016

BUSM researchers uncover genetic, epigenetic alteration overlaps in breast and ovarian cancer

While breast cancer is the most common cause of cancer death in women worldwide, ovarian cancer also is a significant source of mortality as the fifth leading cause of cancer death among women.

24 May 2016

Researchers identify mutations that may stimulate early cancer growth in precancerous colorectal tissue

Researchers at The University of Texas MD Anderson Cancer Center have discovered mutations that may fuel early cancer growth in precancerous colorectal tissue from high-risk patients.

24 May 2016

Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

Scientists of the German Center for Diabetes Research led by the German Institute of Human Nutrition have shown in a mouse model that the epigenetic modification of the Igfbp2 gene observed in the young animal precedes a fatty liver in the adult animal later in life.

24 May 2016

New real-time imaging technique holds great potential in shaping assisted reproduction procedures

Researchers at A*STAR's Institute of Molecular and Cell Biology (IMCB) have developed advanced microscopy technologies to monitor embryo development in real time, revealing how mammalian cells differentiate during the earliest stages of embryonic life.

23 May 2016

Researchers identify trigger for immune cells' inflammatory response

Scientists at the University of Bristol have identified the trigger for immune cells' inflammatory response - a discovery that may pave the way for new treatments for many human diseases.

23 May 2016

Scientists create computational network model to understand human physiology and disease

Scientists at UMass Medical School have created a computational network model that will enable the unraveling of the mechanisms by which different macro- and micronutrients contribute to the physiology of the nematode C. elegans, which is a primary model for understanding human physiology and disease.

23 May 2016

Researchers identify potential ways in which cancer cells may develop resistance to BET inhibitors

A team of Walter and Eliza Hall Institute researchers has worked out how a new class of anti-cancer drugs kills cancer cells, a finding that helps explain how cancer cells may become resistant to treatment.

23 May 2016

Scientists take key step towards understanding link between obesity and physically distant diseases

Obesity is on the rise throughout the world, and in some developed countries two-third of the adult population is either overweight or obese. This brings with it an increased risk of serious conditions such as heart disease, stroke, cancer and osteoarthritis.

23 May 2016

Diet experiments on Lynch syndrome mouse model may help in early detection of colon cancer

Colorectal cancer is the second most common cause of cancer-related deaths in the Western world, mainly because it is usually diagnosed too late. Finding ways to identify those people who are at increased risk of developing colon cancer is therefore crucial, a researcher will tell the annual conference of the European Society of Human Genetics today.

23 May 2016

Genes News and Research

Study provides better understanding of sequence of genetic events in colorectal cancer premalignancy

Sylvester researchers test new KTE-C19 therapy for patients with aggressive non-Hodgkin's lymphoma

Technical advances in neuroimaging offer new promise to clinicians

ANK3 and other genes may play key role in affecting mood, stress and longevity

Scientists study how viral evolution occurs

Vitamin D and androgen receptor-targeted therapy may help treat TNBC

Researchers find genetic mutations linked to increased risk factor for PTSD

BUSM researchers uncover genetic, epigenetic alteration overlaps in breast and ovarian cancer

Researchers identify mutations that may stimulate early cancer growth in precancerous colorectal tissue

Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

New real-time imaging technique holds great potential in shaping assisted reproduction procedures

Researchers identify trigger for immune cells' inflammatory response

Scientists create computational network model to understand human physiology and disease

Researchers identify potential ways in which cancer cells may develop resistance to BET inhibitors

Scientists take key step towards understanding link between obesity and physically distant diseases

Diet experiments on Lynch syndrome mouse model may help in early detection of colon cancer

LIGR-Seq tool opens door to developing new understanding of ncRNA function

Novel protective gene against CAD uncovered

Malicious form of ATF2 protein drives formation of melanoma

New study aims to identify biomarkers linked to cartilage degradation in OA patients

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