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Research roundup: High rates of postdischarge complications; Prescriptions refilled even after discontinued

The authors note that hospitals need detailed data about postdischarge (PD) complications among surgical patients in order to develop "appropriate quality improvement interventions and potentially avoid reimbursement penalties." In attempt to bridge this knowledge gap, researchers from Yale and Stanford Universities evaluated procedure types, rates and risk factors for PD complications occurring within 30 days after 21 groups of inpatient general surgery procedures for more than 500,000 patients.

30 Nov 2012

Infrared therapy could help prevent anal cancer in HIV-positive population

Infrared coagulopathy treatment of a potential precursor of anal cancer is effective and warrants further study as a way to reduce anal cancer incidence and mortality among HIV-infected people, report researchers.

30 Nov 2012

Fully funded Global Fund key to preventing MTCT of HIV

"HIV is the leading cause of death of women of reproductive age," and without HIV, "maternal mortality worldwide would be 20 percent lower," Lucy Chesire, executive director and secretary to the Board of the TB ACTION Group, writes in the Huffington Post's "The Big Push" blog.

30 Nov 2012

UNAIDS, Stop TB Partnership sign memo to work together to halve TB deaths by 2015

UNAIDS and the Stop TB Partnership on Tuesday launched an "initiative aimed at reducing HIV deaths caused by tuberculosis (TB) by half" by 2015, the U.N. News Centre reports.

29 Nov 2012

Review: Omega-3 fatty acids may still help prevent heart disease

Literally hundreds of clinical trials, including some that have gained widespread attention, have been done on the possible benefits of omega-3 fatty acids for the prevention of heart disease - producing conflicting results, varied claims, and frustrated consumers unsure what to believe.

29 Nov 2012

$ACE-inhibitors, angiotensin receptor blockers can treat heart failure with preserved ejection fraction$

ACE-inhibitors, angiotensin receptor blockers can treat heart failure with preserved ejection fraction

A novel study from Karolinska Institutet in Sweden suggests that commonly used drugs to treat heart failure and high blood pressure may have a wider range of application than earlier known, and also can be used against so called HFPEF - a type of heart failure that until now has been impossible to treat.

29 Nov 2012

Bleeding risk modifies perioperative beta-blocker benefits

Perioperative use of beta blockers seems to be beneficial unless patients experience heavy bleeding, in which case it may be detrimental, say researchers.

28 Nov 2012

Digoxin for atrial fibrillation questioned

Experts are calling into question the widespread use of digoxin for atrial fibrillation, in the wake of findings linking the drug to increased mortality.

28 Nov 2012

Hemorrhage risk ‘higher than reported’ for AF warfarin users

Real-world findings for atrial fibrillation patients using warfarin point to a significantly higher risk for hemorrhage than reported for clinical trials.

28 Nov 2012

Warfarin treatment after aortic valve replacement reduces risk of cardiovascular death

Although current guidelines recommend 3 months of anticoagulation treatment after bioprosthetic aortic valve replacement surgery, a study that included more than 4,000 patients found that patients who had warfarin therapy continued between 3 and 6 months after surgery had a lower rate of cardiovascular death, according to a study in the November 28 issue of JAMA.

28 Nov 2012

Diptheria-tetanus-pertussis vaccine: an interview with Dr. Rudi Eggers, World Health Organisation

The Diptheria-tetanus-pertussis vaccine is sometimes also called the “triple vaccine” and has been around for about 50 years, and it protects against diphtheria, tetanus, and pertussis. These are serious diseases caused by bacteria.

28 Nov 2012

IPS examines undernourishment, efforts to reverse vitamin deficiencies

"Poverty is the leading cause of many vitamin deficiencies, especially vitamin A," and the problem is acute in sub-Saharan Africa and South Asia, where food staples such as cassava and rice are high in calories but low in nutrients, Inter Press Service reports.

28 Nov 2012

Patients with RA more likely to have dislocation following hip replacement surgery

In the first systemic review of evidence assessing complications following total joint arthroplasty, patients with rheumatoid arthritis (RA) were found to have an increased risk for hip dislocation after hip replacement surgery compared to those with osteoarthritis (OA). Study findings published online in Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR), also indicate that RA patients have a higher infection risk following total knee replacement than patients with OA.

28 Nov 2012

Intramyocardial injection of organ-derived stem cells after AMI improves left ventricle function

A study published in the current issue of Cell Transplantation, now freely available on-line, has found that when mesenchymal cells derived from skeletal muscle (SM-MSCs) or adipose tissue (ADSCs) were injected into the heart muscle (myocardium) of separate groups of laboratory rats that had suffered a myocardial infarction, rats in both groups experienced significantly improved left ventricle function and smaller infarct size after cell therapy.

28 Nov 2012

State roundup: Conn. official says bulk buying prescription drugs could help budget

The state's chief fiscal watchdog is asking legislators and Gov. Dannel P. Malloy's administration to take a second look at how government purchases prescription medication -- and a proposal he believes could save more than $65 million over the next fiscal year.

28 Nov 2012

Guardian published winning article from International Development Journalism Competition

The Guardian on Sunday published the winning article and a number of shortlisted articles from its International Development Journalism Competition.

28 Nov 2012

THI to launch saliva-based TeloTest in first quarter 2013

Telome Health, Inc. (THI), developer of the TeloTest diagnostic test that measures average telomere length, announces the planned launch of the saliva-based TeloTest in the first quarter of 2013. Related telomere tests, including percentage of short telomeres, would follow.

28 Nov 2012

New recommendations on screening mammography may lead to missed cancers

Researchers assessing the impact of revised guidelines for screening mammography issued by the U.S. Preventive Services Task Force (USPSTF) found evidence that the new recommendations may lead to missed cancers and a decline in screening, according to two studies presented today at the annual meeting of the Radiological Society of North America (RSNA).

27 Nov 2012

Study highlights need for patient education on breast density

A survey of women undergoing routine screening mammography found that many of them would be interested in pursuing additional screening tests if notified they had dense breast tissue, despite the possibility of false positives, invasive procedures, and out-of-pocket costs, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

27 Nov 2012

GW professor receives federal grant to study effects of microsporidia in HIV patients

Imtiaz A. Khan, M.D., professor of microbiology, immunology, and tropical medicine at the George Washington University School of Medicine and Health Sciences, received a $1.6 million federal grant from the National Institute of Allergy and Infectious Diseases to study the effects of microsporidia-opportunistic inter-cellular pathogens-that cause morbidity and mortality in HIV patients.

27 Nov 2012

Mortality News and Research

Research roundup: High rates of postdischarge complications; Prescriptions refilled even after discontinued

Infrared therapy could help prevent anal cancer in HIV-positive population

Fully funded Global Fund key to preventing MTCT of HIV

UNAIDS, Stop TB Partnership sign memo to work together to halve TB deaths by 2015

Review: Omega-3 fatty acids may still help prevent heart disease

ACE-inhibitors, angiotensin receptor blockers can treat heart failure with preserved ejection fraction

Bleeding risk modifies perioperative beta-blocker benefits

Digoxin for atrial fibrillation questioned

Hemorrhage risk ‘higher than reported’ for AF warfarin users

Warfarin treatment after aortic valve replacement reduces risk of cardiovascular death

Diptheria-tetanus-pertussis vaccine: an interview with Dr. Rudi Eggers, World Health Organisation

IPS examines undernourishment, efforts to reverse vitamin deficiencies

Patients with RA more likely to have dislocation following hip replacement surgery

Intramyocardial injection of organ-derived stem cells after AMI improves left ventricle function

State roundup: Conn. official says bulk buying prescription drugs could help budget

Guardian published winning article from International Development Journalism Competition

THI to launch saliva-based TeloTest in first quarter 2013

New recommendations on screening mammography may lead to missed cancers

Study highlights need for patient education on breast density

GW professor receives federal grant to study effects of microsporidia in HIV patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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