Chronic Pain News and Research

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New compound may lead to development of potential therapeutics for neuropathic pain

A new compound discovered by a team of UC Davis investigators has potent actions against production of a chemical that which is implicated in the development of chronic pain following a peripheral nerve injury in the spinal cord.

7 Feb 2015

Study: Acute psychosocial stress has deleterious effect on the body's ability to modulate pain

Traffic slows to a crawl, then a stop. You are trapped in a bottleneck nightmare, and late for a meeting. The stress takes a toll on you psychologically - but your body is at risk as well, according to a Tel Aviv University researcher.

6 Feb 2015

Policymakers need to look beyond painkiller abuse to reduce opioid overdose deaths, say researchers

According to researchers at Brandeis University, the University of North Florida and Johns Hopkins University, policymakers must look beyond painkiller abuse, also called non-medical use, in their efforts to reduce opioid overdose deaths.

5 Feb 2015

Northwestern Medicine researchers evaluate unique surgical method to treat chronic amputee pain

Northwestern Medicine® researchers are leading a new multi-center clinical trial to evaluate a unique surgical method, known as targeted muscle reinnervation (TMR), to treat chronic pain that can result from limb amputation. Around a quarter of all amputees develop chronic pain in the remaining portion of their amputated limb, which can include phantom limb syndrome (pain that is perceived in the portion of the limb that is gone), and prevents many patients from using prostheses.

5 Feb 2015

Nevro obtains new expanded MR-conditional labeling for Senza SCS system

5 Feb 2015

Chronic pain common in affective disorders

Patients with major depressive disorder or bipolar disorder frequently report chronic pain at multiple sites, research shows.

30 Jan 2015

Nevro gets FDA approval letter for Senza spinal cord stimulation system

Nevro Corp., a medical device company that has developed and commercialized an innovative, evidence-based neuromodulation platform for the treatment of chronic pain, today announced that it has received a letter from the U.S. Food and Drug Administration informing the company of the approvability of its Premarket Approval Application (PMA) for the Senza spinal cord stimulation (SCS) system.

23 Jan 2015

Two new drug compounds appear to be effective in treating endometriosis

Two new drug compounds - one of which has already proven useful in a mouse model of multiple sclerosis - appear to be effective in treating endometriosis, a disorder that, like MS, is driven by estrogen and inflammation, scientists report in Science Translational Medicine.

22 Jan 2015

Controlling acute and chronic pain in women

Despite the variety of effective treatments, and physicians who specialize in treating pain, women often suffer unnecessarily from conditions ranging from backaches to pain after cancer surgery, and also treat their pain with medications that may be ineffective and possibly harmful, according to a review of research related to women and pain by the American Society of Anesthesiologists.

20 Jan 2015

Individualized, patient-centered care needed to treat and monitor people with chronic pain

An independent panel convened by the National Institutes of Health concluded that individualized, patient-centered care is needed to treat and monitor the estimated 100 million Americans living with chronic pain. To achieve this aim, the panel recommends more research and development around the evidence-based, multidisciplinary approaches needed to balance patient perspectives, desired outcomes, and safety.

14 Jan 2015

Study finds unnecessary hysterectomy in 1 out of 5 cases

It is estimated that one in three women in the United States will have had a hysterectomy by the age of 60. Although the numbers of hysterectomies are decreasing, a new study of more than three thousand women in Michigan who underwent hysterectomy for benign indications reveals that alternatives to hysterectomy are being underused and that treatment guidelines are often not followed.

7 Jan 2015

Crealta publishes review of post-hoc safety analysis completed for Krystexxa

Crealta Pharmaceuticals LLC, today announced that the Journal of Clinical Rheumatology published a comprehensive review of a post-hoc safety analysis that was completed for Krystexxa (pegloticase), including data from the two pivotal randomized Phase III trials and one open-label extension trial.

14 Dec 2014

Boston Scientific Precision Spectra SCS System provides sustained relief for low back pain patients

New retrospective data evaluating the Boston Scientific Corporation Precision Spectra Spinal Cord Stimulator (SCS) System demonstrate that the device provided sustained, highly significant relief of low back pain 12 months after implantation.

14 Dec 2014

MOVENTIG (naloxegol) receives EC approval for treatment of opioid-induced constipation

Nektar Therapeutics reported partner AstraZeneca today announced that MOVENTIG (naloxegol) has been granted Marketing Authorisation by the European Commission for the treatment of opioid-induced constipation (OIC) in adult patients who have had an inadequate response to laxative(s).

9 Dec 2014

Doctors prescribe fewer opioids for pain as prescription drug abuse rises

Nine in 10 primary care physicians say that prescription drug abuse is a moderate or big problem in their communities and nearly half say they are less likely to prescribe opioids to treat pain compared to a year ago, new Johns Hopkins Bloomberg School of Public Health research suggests.

9 Dec 2014

Researchers identify important neural mechanism responsible for certain chronic pain disorders

Pain typically has a clear cause-but not always. When a person touches something hot or bumps into a sharp object, it's no surprise that it hurts. But for people with certain chronic pain disorders, including fibromyalgia and phantom limb pain, a gentle caress can result in agony.

6 Dec 2014

University of Utah professor develops MORE intervention program for chronic pain patients

How can people who are dependent on prescription opioids reduce their cravings? Learn to enjoy other aspects of their lives.

6 Dec 2014

University of Miami researcher reveals association between 'salience processing' and brain disorders

How does the brain determine what matters? According to a new scientific article, a brain structure called the insula is essential for selecting things out of the environment that are "salient" for an individual, and dysfunction of this system is linked to brain disorders such as autism, psychosis and dementia.

5 Dec 2014

TSRI scientists identify 'mechanoreceptor' protein that mediates sense of touch in mammals

A team led by biologists at The Scripps Research Institute has solved a long-standing mystery in neuroscience by identifying the "mechanoreceptor" protein that mediates the sense of touch in mammals.

5 Dec 2014

SLU researcher discovers way to block pain pathway

In research published in the medical journal Brain, Saint Louis University researcher Daniela Salvemini, Ph.D. and colleagues within SLU, the National Institutes of Health and other academic institutions have discovered a way to block a pain pathway in animal models of chronic neuropathic pain including pain caused by chemotherapeutic agents and bone cancer pain suggesting a promising new approach to pain relief.

27 Nov 2014

Chronic Pain News and Research

New compound may lead to development of potential therapeutics for neuropathic pain

Study: Acute psychosocial stress has deleterious effect on the body's ability to modulate pain

Policymakers need to look beyond painkiller abuse to reduce opioid overdose deaths, say researchers

Northwestern Medicine researchers evaluate unique surgical method to treat chronic amputee pain

Nevro obtains new expanded MR-conditional labeling for Senza SCS system

Chronic pain common in affective disorders

Nevro gets FDA approval letter for Senza spinal cord stimulation system

Two new drug compounds appear to be effective in treating endometriosis

Controlling acute and chronic pain in women

Individualized, patient-centered care needed to treat and monitor people with chronic pain

Study finds unnecessary hysterectomy in 1 out of 5 cases

Crealta publishes review of post-hoc safety analysis completed for Krystexxa

Boston Scientific Precision Spectra SCS System provides sustained relief for low back pain patients

MOVENTIG (naloxegol) receives EC approval for treatment of opioid-induced constipation

Doctors prescribe fewer opioids for pain as prescription drug abuse rises

Researchers identify important neural mechanism responsible for certain chronic pain disorders

University of Utah professor develops MORE intervention program for chronic pain patients

University of Miami researcher reveals association between 'salience processing' and brain disorders

TSRI scientists identify 'mechanoreceptor' protein that mediates sense of touch in mammals

SLU researcher discovers way to block pain pathway

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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