Experts discuss therapeutic potential of medical cannabis in a symposium organized by MUHC

While debate about recreational marijuana use continues, researchers are investigating the effectiveness of cannabis for treating pain, spasticity, and a host of other medical problems. In a symposium organized by the McGill University Health Centre (MUHC) as part of the 2015 American Association for the Advancement of Science Annual Meeting held this week in San Jose, California, world-renowned experts from North America and the U.K. share their perspectives on the therapeutic potential of medical cannabis and explore the emerging science behind it.

"We need to advance our understanding of the role of cannabinoids in health and disease through research and education for patients, physicians and policy-makers," says Dr. Mark Ware, director of clinical research at the Alan Edwards Pain Management Unit at the MUHC, in Canada.

As a pain specialist Dr. Ware regularly sees patients with severe chronic pain at his clinic in Montreal, and for some of them, marijuana appears to be a credible option. "I don't think that every physician should prescribe medical cannabis, or that every patient can benefit but it's time to enhance our scientific knowledge base and have informed discussions with patients."

Increasing numbers of jurisdictions worldwide are allowing access to herbal cannabis, and a range of policy initiatives are emerging to regulate its production, distribution, and authorization. It is widely believed that there is little evidence to support the consideration of cannabis as a therapeutic agent. However, several medicines based on tetrahydrocannabinol (THC), the psychoactive ingredient of cannabis, have been approved as pharmaceutical drugs.

Leading British cannabis researcher Professor Roger Pertwee, who co-discovered the presence of tetrahydrocannabivarin (THCV) in cannabis in the 70's, recently published with collaborators some findings of potential therapeutic relevance in the British Journal of Pharmacology. "We observed that THCV, the non-psychoactive component of cannabis, produces anti-schizophrenic effects in a preclinical model of schizophrenia," says Pertwee, professor of Neuropharmacology at Aberdeen University. "This finding has revealed a new potential therapeutic use for this compound."

Neuropsychiatrist and Director of the Center for Medicinal Cannabis Research (CMCR) at the University of California, San Diego Dr. Igor Grant is interested in the short and long-term neuropsychiatric effects of marijuana use. The CMCR has overseen some of the most extensive research on the therapeutic effects of medical marijuana in the U.S. "Despite a commonly held view that cannabis use results in brain damage, meta analyses of extensive neurocognitive studies fail to demonstrate meaningful cognitive declines among recreational users," says Dr. Grant. "Bain imaging has produced variable results, with the best designed studies showing null findings."

Dr. Grant adds that while it is plausible to hypothesize that cannabis exposure in children and adolescents could impair brain development or predispose to mental illness, data from properly designed prospective studies is lacking.

Source:

McGill University Health Centre

Comments

  1. Jeff Deutsch Jeff Deutsch United States says:

    I'm a Scientist with a strong interest in Cancer research. The clinical evidence of the value of Marijuana as a life saving medicine is now so strong that the need to remove Marijuana from Schedule 1 has become a moral imperative. Google Medical Marijuana testimonials. Google Medical Marijuana Cancer Patient Testimonials.

    This weekend over 3,000 Americans died, in pain, of Cancer. Every day after that, 1,500 more Americans will die, after suffering horribly, from it. Every single minute another American dies of Cancer. Every American Cancer patient deserves the right to have safe, legal, and economical access to Medical Marijuana. Every single one.

    Americans who need Medical Marijuana shouldn't be used as "Political Footballs" Please call the Whitehouse comment line at (202) 456-1111 and ask that the President take immediate action to remove Marijuana from Schedule 1 so American Physicians in all 50 states can prescribe it.

    Oncologists have know it for more than a quarter of a Century that Marijuana is a "wonder drug" for helping Cancer patients.

    The American Society of Clinical Oncologists wants Marijuana removed from Schedule 1. So does the American Medical Association, the professional society of all Physicians. A strong majority of Americans want Physicians in all 50 states to be able to prescribe Medical Marijuana. So do their Physicians., Cancer patients can't wait.

    The need to immediately, completely, legalize Marijuana throughout the world is one of the most pressing moral issues of our time, because of its medical benefits and because of the damage prohibition causes to America and to the world.

    Complete legalization is critical -- its vital that there aren't "strings" or "hoops" that Cancer patients and others who need Medical Marijuana are forced to jump through.

    "Charlottes web" is NOT the solution. Cancer patients and people who suffer from chronic pain need THC, not just CBD. The "Berkeley study", where 96% of stage 4 Cancer patients who had a wide variety of Cancers achieved remission, used high dose Medical Marijuana oil, 72% THC, 28% CBD, 1 gram/day (oral) over a 90 day course of treatment. It was a small study, and not placebo controlled, but those kinds of results are clearly remarkable, have been widely reported on in the press, and demand the need for immediate large scale clinical trials.

    More and more present and former members of law enforcement agree about the need to end prohibition, and have formed a rapidly expanding group of current and former undercover cops, FBI, DEA, prosecutors and Judges, from all over the world, called

    LEAP -- Law Enforcement Against Prohibition

    because they've seen the damage prohibition causes to America and the world.

    See http://www.leap.cc/

    I'm a Scientist. Not a politician, not a cop.

    But as a Scientist with a strong interest in Cancer research, I feel even more strongly about the need to ensure that no Cancer patient is denied it, because I'm so impressed with its benefits for Cancer patients.

    I urge everyone reading this to PLEASE call and email the Attorney General, the press, Congress and the President today.

    Medical Marijuana helps with Alzheimer's, Autism, Cancer, seizures, PTSD and chronic pain, and has helped many Americans, including many veterans, stop using Alcohol, and hard drugs, both legal and illegal ones.

    Every minute an American dies of Cancer.

    Every 19 minutes an American dies of a prescription drug overdose.

    Many vets become addicted to prescription opiates and die from them.

    NOBODY has ever died from smoking too much pot.

    Cancer patients are seeing remarkable results using high dose Medical Marijuana oil, in many cases achieving complete remission, even for stage 4 cancers -- there are many excellent articles on the web, and videos on youtube with patient's personal stories about their experiences with it -- and every Cancer patient that uses Marijuana to ease their suffering benefits greatly from doing so.

    It is immoral to leave Marijuana illegal, for anyone, for even a second longer.

    For Cancer patients, its a matter of life and death.

    Cancer patients can't wait.

    Medical Marijuana has an unmatched safety profile, and for people who suffer from so many diseases, of so many kinds, its a medical miracle -- and the scientific evidence behind it is rock solid.

    For Cancer patients, Medical Marijuana encourages apoptosis and autophagy of Cancer cells, while leaving normal cells untouched, is anti-angigogenic, anti-proliferative, and is anti-angiogenic.

    Its also synergistic with chemotherapy and radiation therapy, making both more effective.

    For many Cancer patients its meant the difference between life and death.

    For everyone else, its a far safer alternative to Alcohol, and infinitely safer than Cigarettes.

    Either take them off the market too, or legalize Marijuana right now.

    2016 is too far away, Its too long to wait. Every year we lose more Americans to Cancer than died in WWII.

    Between now and the 2016 elections, roughly 1 MILLION Americans will die of Cancer.

    And Its a horrible way to die.

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News-Medical.Net.
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