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First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

The real-world safety and efficacy of sacituzumab govitecan (SG) against metastatic triple-negative breast cancer.

26 Apr 2024

Study: Antibiotic use in moderate COVID-19 linked to clinical deterioration

Antibiotic treatment of adults hospitalized with moderate COVID-19 is associated with clinical deterioration, despite the drugs being given to over 40% of patients, according to new research being presented at this year's ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April)

25 Apr 2024

Medicare warning letters effectively cut antipsychotic prescribing for dementia patients

Warning letters from Medicare can safely cut prescribing of a powerful but risky antipsychotic, according to a new study at Columbia University Mailman School of Public Health.

25 Apr 2024

MIT study reveals circadian impact on drug metabolism in engineered livers

Giving drugs at different times of day could significantly affect how they are metabolized in the liver, according to a new study from MIT.

25 Apr 2024

New system personalizes chemotherapy doses for cancer patients

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that was formulated from data on just nine patients.

24 Apr 2024

Study links acid-reducing drugs to increased risk of migraine

People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a study published in the April 24, 2024, online issue of Neurology Clinical Practice, an official journal of the American Academy of Neurology.

24 Apr 2024

Anesthetic midazolam boosts survival after cardiac arrest

If a patient is successfully resuscitated after a cardiac arrest and circulation resumes, they are not out of the woods yet.

24 Apr 2024

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Intranasal administration of neomycin sulfate in murine models shows promise as a prophylactic and therapeutic agent against respiratory viruses like influenza A and SARS-CoV-2 by inducing interferon-stimulated gene (ISG) expression, independent of microbiota and interferon activation.

24 Apr 2024

Research highlights best window for paxlovid administration in COVID-19 patients

Researchers have described the optimal timing for COVID-19 patients to take the antiviral, Paxlovid, to get the most benefit from the treatment, according to a study published April 16 in eLife.

23 Apr 2024

FDA approval of Anktiva heralds a new era in the treatment of BCG-unresponsive non–muscle-invasive bladder cancer

The U.S. Food and Drug Administration (FDA) has approved the immunotherapy-boosting drug N-803, which is marketed under the brand name Anktiva, to be used in combination with the immunotherapy Bacillus Calmette-Guerin (BCG) for the treatment of patients with BCG-unresponsive non–muscle-invasive bladder cancer.

23 Apr 2024

Investigating the efficacy and safety of existing drugs in patients with rare immune diseases

This month the first study within the DRIMID consortium (DRIMID stands for Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases) has started.

23 Apr 2024

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

Tafenoquine, a prodrug that could fulfill the criteria for a mass eradication campaign.

23 Apr 2024

Study uncovers aspirin's role in colorectal cancer development and progression

Long-term daily use of aspirin can help to prevent the development and progression of colorectal cancer, but the mechanisms involved have been unclear.

22 Apr 2024

Blessed thistle compound Cnicin speeds nerve growth, study finds

Blessed thistle (Cnicus benedictus) is a plant in the family Asteraceae and also grows in our climate. For centuries, it has been used as a medicinal herb as an extract or tea, e.g. to aid the digestive system.

22 Apr 2024

Monoclonal antibody Prasinezumab shows promise in slowing rapid Parkinson's progression

A recent study in Nature Medicine evaluated the efficacy of prasinezumab, a monoclonal antibody, in slowing the progression of motor symptoms in Parkinson’s disease patients with rapidly progressing forms, using phase II clinical trial data.

19 Apr 2024

Study shows antipsychotic drugs increase health risks in dementia patients

Study found that antipsychotic drug use in dementia patients is linked to increased risks of stroke, heart failure, and other serious conditions.

18 Apr 2024

ChatGPT shows promise in polypharmacy management

Polypharmacy, or the concurrent use of five or more medications, is common in older adults and increases the risk of adverse drug interactions.

18 Apr 2024

Antipsychotics for dementia associated with elevated risks of serious adverse outcomes

Antipsychotic use in people with dementia is associated with elevated risks of a wide range of serious adverse outcomes including stroke, blood clots, heart attack, heart failure, fracture, pneumonia, and acute kidney injury, compared with non-use, finds a study published by The BMJ today.

17 Apr 2024

New vaccine promises broad protection against SARS-CoV-2 and other sarbecoviruses

Researchers at Georgia Tech and the University of Wisconsin have created a broad-spectrum vaccine capable of defending against various SARS-CoV-2 variants and related bat coronaviruses.

17 Apr 2024

To stop fentanyl deaths in Philadelphia, knocking on doors and handing out overdose kits

On a narrow street lined with row houses and an auto body shop in the Kensington neighborhood of North Philadelphia, Marsella Elie climbs a home's front steps and knocks hard on the door.

17 Apr 2024

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Pharmaceutical News

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

Study: Antibiotic use in moderate COVID-19 linked to clinical deterioration

Medicare warning letters effectively cut antipsychotic prescribing for dementia patients

MIT study reveals circadian impact on drug metabolism in engineered livers

New system personalizes chemotherapy doses for cancer patients

Study links acid-reducing drugs to increased risk of migraine

Anesthetic midazolam boosts survival after cardiac arrest

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Research highlights best window for paxlovid administration in COVID-19 patients

FDA approval of Anktiva heralds a new era in the treatment of BCG-unresponsive non–muscle-invasive bladder cancer

Investigating the efficacy and safety of existing drugs in patients with rare immune diseases

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

Study uncovers aspirin's role in colorectal cancer development and progression

Blessed thistle compound Cnicin speeds nerve growth, study finds

Monoclonal antibody Prasinezumab shows promise in slowing rapid Parkinson's progression

Study shows antipsychotic drugs increase health risks in dementia patients

ChatGPT shows promise in polypharmacy management

Antipsychotics for dementia associated with elevated risks of serious adverse outcomes

New vaccine promises broad protection against SARS-CoV-2 and other sarbecoviruses

To stop fentanyl deaths in Philadelphia, knocking on doors and handing out overdose kits

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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