Pharmaceutical News

RSS

Machine learning advances human-centric drug toxicity prediction

In the UK, there was a case where TGN1412, an immunotherapy under development, triggered a cytokine storm within hours of administration to humans, leading to multiple organ failure.

7 Nov 2025

UniSA launches pilot effort to make medicines safer for older Australians

In a national effort to make medicines safer for older Australians, the University of South Australia is calling for aged care providers and pharmacists to join a new pilot study to assess medication safety and management in residential aged care.

6 Nov 2025

Over-the-counter pain relievers outperform opioids after wisdom tooth extraction

Over-the-counter pain medications work as well or better than opioids after wisdom tooth extraction for both men and women, according to a Rutgers Health-led follow-up to a landmark paper on comparative pain relief.

6 Nov 2025

New evidence reassures safety of acetaminophen use during pregnancy

A rigorous systematic review of the present state of knowledge on the use of acetaminophen during pregnancy and the risk of specific neurodevelopmental disorders (NDDs), such as autism and ADHD, offers reassurance that acetaminophen does not increase the risk of NDDs.

6 Nov 2025

Finerenone offers hope for kidney protection in patients with type 1 diabetes

The drug finerenone has a positive effect on patients with type 1 diabetes and chronic kidney disease.

6 Nov 2025

Researchers identify patient response patterns to novel schizophrenia medication

Each year, about 100,000 Americans experience psychosis, a serious condition that disrupts thoughts and perceptions so profoundly that it can distort a person's sense of reality.

6 Nov 2025

Opioid receptors caught in motion offering clues for safer painkillers

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced "mew-opioid") receptors. What they didn't know - until now - was exactly what happens next.

5 Nov 2025

Common cholesterol drugs found to speed up PFAS removal from the body

Certain medicines can cause the environmental toxin PFAS to be eliminated from the body faster, according to a study at the University of Gothenburg.

4 Nov 2025

Do GLP-1 drugs cause cancer? New review says no, may even protect

A comprehensive review in The Journal of Clinical Investigation finds no overall link between GLP-1 receptor agonists and increased cancer risk, countering early safety concerns. Instead, evidence suggests possible protective effects for certain cancers, supported by metabolic and immune-modulating mechanisms.

4 Nov 2025

GLP-1 drugs calm inflammation beyond diabetes and weight loss

This Journal of Clinical Investigation review describes how glucagon-like peptide-1 (GLP-1)–based medicines reduce systemic and tissue inflammation through both weight-dependent and weight-independent mechanisms. It details preclinical and clinical evidence linking GLP-1 receptor activation to cardiovascular, renal, hepatic, neural, and joint anti-inflammatory effects while outlining uncertainties and future research needs.

4 Nov 2025

Low-dose aspirin helps reduce the incidence of major cardiovascular event among diabetic individuals

People with Type 2 diabetes (T2D) and an elevated risk for cardiovascular disease (CVD) who took low-dose aspirin were less likely to experience a major cardiovascular event, including heart attack, stroke or death, than people with T2D at similar CVD risk who did not take low-dose aspirin, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2025.

3 Nov 2025

Long-term use of melatonin supplements linked to higher risk of heart failure and death

Long-term use of melatonin supplements, often used to promote sleep and address insomnia, was associated with a higher risk of heart failure diagnosis, heart failure hospitalization and death from any cause in chronic insomnia, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2025.

3 Nov 2025

Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway

Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.

30 Oct 2025

Diabetes remission possible with GLP-1 drugs, Italian study confirms

In a large real-world Italian cohort, GLP-1 receptor agonist therapy led to measurable rates of type 2 diabetes remission, depending on how remission was defined. The most pragmatic definition (Remission 3) was linked to improved glycemia, weight, and a lower risk of microvascular and cardiovascular events.

29 Oct 2025

New genetic marker may improve the ability to predict life-threatening reactions to gout medication

A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication allopurinol in U.S. patients.

29 Oct 2025

New imaging technique maps medication distribution across skin layers

A new study by the Hebrew University has developed a rapid imaging method that reveals how drugs move through the skin, in just ten minutes.

29 Oct 2025

Two analgesic drugs may one day be repurposed as anti-tumor therapies

Peripheral afferent neurons - nerves that send signals from all areas of the body to the central nervous system (brain and spinal cord) - are known to infiltrate and grow within malignant bone tumors called osteosarcomas, often accompanied by severe pain.

29 Oct 2025

Reducing prescriptions of sleep drugs in older adults could provide health and economic benefits

Millions of older Americans suffering from insomnia regularly use prescription sleep medications, despite the risk of serious side effects-such as falls, broken bones

28 Oct 2025

Study highlights need to establish clinical practice guidelines for surgical patients receiving MOUDs

In an effort to stem the death toll from opioid overdose, United States public health officials have promoted the prescription and use of medications like buprenorphine that blunt the effects of illicit opioids such as fentanyl.

27 Oct 2025

Research shows a decline in opioid dispensing across Canadian provinces

Efforts to promote safer opioid prescribing in Canada appear to be having an effect, as new research in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.250670 shows a decrease in opioid dispensing between 2018 and 2022.

27 Oct 2025

Pharmaceutical News

Machine learning advances human-centric drug toxicity prediction

UniSA launches pilot effort to make medicines safer for older Australians

Over-the-counter pain relievers outperform opioids after wisdom tooth extraction

New evidence reassures safety of acetaminophen use during pregnancy

Finerenone offers hope for kidney protection in patients with type 1 diabetes

Researchers identify patient response patterns to novel schizophrenia medication

Opioid receptors caught in motion offering clues for safer painkillers

Common cholesterol drugs found to speed up PFAS removal from the body

Do GLP-1 drugs cause cancer? New review says no, may even protect

GLP-1 drugs calm inflammation beyond diabetes and weight loss

Low-dose aspirin helps reduce the incidence of major cardiovascular event among diabetic individuals

Long-term use of melatonin supplements linked to higher risk of heart failure and death

Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway

Diabetes remission possible with GLP-1 drugs, Italian study confirms

New genetic marker may improve the ability to predict life-threatening reactions to gout medication

New imaging technique maps medication distribution across skin layers

Two analgesic drugs may one day be repurposed as anti-tumor therapies

Reducing prescriptions of sleep drugs in older adults could provide health and economic benefits

Study highlights need to establish clinical practice guidelines for surgical patients receiving MOUDs

Research shows a decline in opioid dispensing across Canadian provinces

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

Latest News