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FDA approves daraxonrasib for metastatic pancreatic cancer following landmark clinical trial led by Dana-Farber

The U.S. Food and Drug Administration (FDA) has approved daraxonrasib, an oral multi-selective RAS(ON) inhibitor, for adults with metastatic pancreatic adenocarcinoma who have received at least one prior systemic therapy or are not candidates for multiagent systemic therapy.

From Dana-Farber Cancer Institute, Inc. 29 Aug 2026

Rapid rise of GLP-1 medicines brings obesity and eating disorders together

Obesity and eating disorders have traditionally been treated as separate areas of healthcare – but the rapid rise of GLP-1 medicines is increasingly bringing the two together.

28 Aug 2026

African Bundibugyo ebolavirus vaccine candidate to be advanced to clinical trials

Leading African biopharmaceutical company Minapharm Group, headquartered in Egypt with subsidiaries in Berlin, will receive up to US$16.5 million from the Coalition for Epidemic Preparedness Innovations (CEPI) to advance the development of a Bundibugyo ebolavirus vaccine candidate, strengthening efforts to develop vaccines to combat the fastest-growing and second-largest Ebola outbreak on record affecting the Democratic Republic of the Congo (DRC).

28 Aug 2026

Blood-brain barrier-crossing blood pressure drugs linked to lower dementia risk

In a large Australian cohort of adults with hypertension, use of blood-brain barrier-crossing antihypertensive medications was associated with a lower risk of dementia and mortality than use of non-crossing drugs. The association was strongest for beta-blockers and angiotensin II receptor blockers, although the observational design means the findings cannot establish causality.

27 Aug 2026

The US switch in shingles vaccines revealed an unexpected heart health pattern

In a natural experiment involving 72,920 propensity-matched US adults aged 60 years and older, recombinant shingles vaccination was associated with a 9% lower cardiovascular disease burden over seven years compared with the live attenuated vaccine. Lower burdens of ischemic heart disease and heart failure were seen in both sexes, while ischemic stroke was significantly lower only among men, supporting further clinical trials and mechanistic studies

27 Aug 2026

Study reveals how SGLT2 inhibitors improve failing heart function

Researchers have discovered that SGLT2 inhibitors, a class of drugs originally developed to treat diabetes and now widely used for heart failure, work by activating a key enzyme that helps heart cells produce and use energy more efficiently.

27 Aug 2026

Pomegranate phytobiotics offer natural alternative to synthetic veterinary drugs

Researchers have identified a broad range of biological properties in pomegranate with potential for use in medical applications, including antimicrobial, antiparasitic, antioxidant, immunomodulatory, antidiabetic, anti-inflammatory, liver-supporting, and wound-healing effects.

27 Aug 2026

Biosimilars reduce financial burden for cancer patients and insurers

Biologic drugs play an important role in treating cancers such as breast cancer and lymphoma, but their high costs can add to the financial burden of cancer care.

27 Aug 2026

Missing doses of antihypertensive medication erase life-saving cardiovascular benefits

The true impact of missing doses of blood pressure-lowering medication will be demonstrated in a presentation at ESC Congress 2026.

27 Aug 2026

Former ESC president judged guilty of severe misconduct over drug ties

A British cardiologist and former president of the European Society of Cardiology (ESC) has been judged by the ESC to have committed severe misconduct after a Danish TV documentary reported that he had been involved in drawing up guidelines for the use of the heart drug ivabradine (Corlanor, Procoralan) while profiting from lucrative contracts with the drug's maker.

27 Aug 2026

FDA approves first RAS-targeted therapy for metastatic pancreatic cancer

27 Aug 2026

Metformin cuts preterm birth risk among high-risk mothers

A common diabetes medication can reduce the risk of early and preterm births for mothers at high metabolic risk, according to new research led by Monash University.

26 Aug 2026

GLP-1 drugs may reshape obesity care, but clinicians still have questions

Interviews with 11 healthcare professionals in a UK specialist weight management service found generally positive attitudes toward injectable GLP-1 drugs, alongside limited formal training and uncertainty about how the medications should be integrated with behavioral care. Participants anticipated potential benefits for confidence and weight management but also raised concerns about treatment discontinuation, behavioral engagement, and evolving professional responsibilities.

26 Aug 2026

Nigerian COVID-19 response highlights cultural trust in ethnopharmacology

During COVID-19, ethnopharmacology became prominent in Nigeria due to affordability, accessibility, and cultural trust, but evidence for safety and efficacy remains limited.

25 Aug 2026

Researchers link GLP-1 drugs to lower tuberculosis risk in type 2 diabetes

A large retrospective cohort study found that GLP-1 receptor agonist use was associated with a lower risk of tuberculosis in people with type 2 diabetes compared with sulfonylureas, metformin, DPP-4 inhibitors, and SGLT2 inhibitors. The observational findings suggest a possible benefit beyond metabolic control, but the authors emphasize that prospective and mechanistic studies are needed to determine whether GLP-1 therapies themselves reduce TB risk.

24 Aug 2026

Japan vaccinated heavily during COVID-19. Why are so many unsure about vaccinating next time?

A nationwide Japanese survey found that only 53.1% of respondents said they would accept vaccination in a hypothetical future pandemic with COVID-19-like fatality, despite substantially higher previous COVID-19 vaccine uptake. Willingness varied by demographics, perceived disease risk, exposure to misinformation, vaccine characteristics, and practical factors such as cost, evidence, professional recommendations, and accessibility.

24 Aug 2026

Semaglutide’s heart benefits may partly involve reduced inflammation

A prespecified analysis of 17,604 SELECT participants found that higher baseline hsCRP was associated with greater risks of major cardiovascular events and death in people with overweight or obesity and established cardiovascular disease. Semaglutide produced rapid and sustained reductions in hsCRP, with changes emerging before substantial weight loss, although the study could not establish whether reduced inflammation directly mediated its cardiovascular benefits.

24 Aug 2026

Potassium-competitive acid blockers match proton pump inhibitors for preventing bleeding after PCI

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) increases the risk of upper gastrointestinal bleeding (UGIB).

20 Aug 2026

Why pregnancy vaccination looks very different in Germany than it did 19 years ago

A 19-year German claims analysis of more than 2.8 million pregnancies found that recorded maternal vaccination increased substantially after national recommendations for influenza and pertussis immunization were introduced. Influenza vaccination reached 19.4% and pertussis vaccination about 37% in 2020-2022, while COVID-19 vaccination was not captured in the databas

19 Aug 2026

Most Americans still believe outdated antibiotic guidance, study finds

"Always finish your antibiotics" is no longer considered medical best practice for all conditions.

13 Aug 2026

Pharmaceutical News

FDA approves daraxonrasib for metastatic pancreatic cancer following landmark clinical trial led by Dana-Farber

Rapid rise of GLP-1 medicines brings obesity and eating disorders together

African Bundibugyo ebolavirus vaccine candidate to be advanced to clinical trials

Blood-brain barrier-crossing blood pressure drugs linked to lower dementia risk

The US switch in shingles vaccines revealed an unexpected heart health pattern

Study reveals how SGLT2 inhibitors improve failing heart function

Pomegranate phytobiotics offer natural alternative to synthetic veterinary drugs

Biosimilars reduce financial burden for cancer patients and insurers

Missing doses of antihypertensive medication erase life-saving cardiovascular benefits

Former ESC president judged guilty of severe misconduct over drug ties

FDA approves first RAS-targeted therapy for metastatic pancreatic cancer

Metformin cuts preterm birth risk among high-risk mothers

GLP-1 drugs may reshape obesity care, but clinicians still have questions

Nigerian COVID-19 response highlights cultural trust in ethnopharmacology

Researchers link GLP-1 drugs to lower tuberculosis risk in type 2 diabetes

Japan vaccinated heavily during COVID-19. Why are so many unsure about vaccinating next time?

Semaglutide’s heart benefits may partly involve reduced inflammation

Potassium-competitive acid blockers match proton pump inhibitors for preventing bleeding after PCI

Why pregnancy vaccination looks very different in Germany than it did 19 years ago

Most Americans still believe outdated antibiotic guidance, study finds

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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