Pharmaceutical News

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No, taking paracetamol while pregnant doesn’t cause autism or ADHD, major review finds

Researchers reviewed nine systematic reviews on paracetamol use during pregnancy and found that while some studies suggested links to ADHD or autism, the evidence was of low quality and confounded by shared familial factors. Sibling-controlled analyses showed no causal relationship between prenatal paracetamol exposure and neurodevelopmental disorders in children.

11 Nov 2025

Evolocumab shows clear benefit in preventing first-time heart attacks and strokes

Adding the PCSK9 inhibitor evolocumab to standard lipid-lowering therapy significantly reduced first major cardiovascular events in adults with atherosclerosis or high-risk diabetes who had never had a heart attack or stroke. The 4.6-year study confirmed durable safety and benefit, supporting earlier, more intensive LDL cholesterol control.

11 Nov 2025

GLP-1 drugs linked to improved survival in colon cancer patients

A new University of California San Diego study offers compelling evidence that glucagon-like peptide-1 (GLP-1) receptor agonists - the class of drugs behind Ozempic, Wegovy and Mounjaro, for example - may do more than regulate blood sugar and weight.

11 Nov 2025

Study warns of unsafe antiseizure drug use despite rising access

In a study carried out in collaboration with the World Health Organization, two Aston University academics have found that while access to antiseizure medication in low- and middle-income countries is growing, it is not necessarily always prescribed safely.

11 Nov 2025

New drug combination gains Fast Track Designation for metastatic colorectal cancer

The U.S. Food and Drug Administration has granted Fast Track Designation to a new drug combination for metastatic colorectal cancer, following encouraging results from a clinical trial led in part by the University of Oklahoma Health Stephenson Cancer Center.

10 Nov 2025

GLP-1 drugs beat metformin for weight control in teens with type 2 diabetes

In youth newly diagnosed with type 2 diabetes, GLP-1–based therapies, including semaglutide and tirzepatide, achieved similar blood sugar control but significantly greater reductions in body mass index than metformin. These findings highlight the potential of high-potency GLP-1 agents as effective monotherapy options in managing obesity and glycemic control in adolescents.

10 Nov 2025

Diabetes drugs semaglutide and tirzepatide show real-world heart benefits

In a large real-world analysis across three U.S. healthcare databases, semaglutide and tirzepatide showed cardiovascular benefits consistent with randomized trials. Semaglutide lowered heart attack and stroke risk versus sitagliptin, while tirzepatide performed comparably to dulaglutide and semaglutide over one year.

10 Nov 2025

PCSK9 inhibitor combined with a statin may help reduce LDL cholesterol after heart transplant

The cholesterol medication alirocumab, a PCSK9 inhibitor, combined with a statin appeared to reduce LDL cholesterol levels by more than 50% among patients after a heart transplant, according to a late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Weight loss drugs used by patients with high triglycerides do not increase pancreatitis risk

In a major new study, researchers from Intermountain Health in Salt Lake City have found that weight loss drugs used by patients who have high triglycerides do not increase their risk of pancreatitis or adverse cardiac events.

10 Nov 2025

Diabetes drug blunts exercise-induced health improvements

A widely prescribed diabetes drug may be sabotaging one of the most trusted strategies for preventing the disease: exercise.

7 Nov 2025

Study reveals uneven access to abortion pill mifepristone in British Columbia

Most pharmacies in British Columbia can provide the abortion pill mifepristone within days, but uneven access still leaves some women facing barriers to this time-sensitive medication, according to new research.

7 Nov 2025

Machine learning advances human-centric drug toxicity prediction

In the UK, there was a case where TGN1412, an immunotherapy under development, triggered a cytokine storm within hours of administration to humans, leading to multiple organ failure.

7 Nov 2025

UniSA launches pilot effort to make medicines safer for older Australians

In a national effort to make medicines safer for older Australians, the University of South Australia is calling for aged care providers and pharmacists to join a new pilot study to assess medication safety and management in residential aged care.

6 Nov 2025

Over-the-counter pain relievers outperform opioids after wisdom tooth extraction

Over-the-counter pain medications work as well or better than opioids after wisdom tooth extraction for both men and women, according to a Rutgers Health-led follow-up to a landmark paper on comparative pain relief.

6 Nov 2025

New evidence reassures safety of acetaminophen use during pregnancy

A rigorous systematic review of the present state of knowledge on the use of acetaminophen during pregnancy and the risk of specific neurodevelopmental disorders (NDDs), such as autism and ADHD, offers reassurance that acetaminophen does not increase the risk of NDDs.

6 Nov 2025

Finerenone offers hope for kidney protection in patients with type 1 diabetes

The drug finerenone has a positive effect on patients with type 1 diabetes and chronic kidney disease.

6 Nov 2025

Researchers identify patient response patterns to novel schizophrenia medication

Each year, about 100,000 Americans experience psychosis, a serious condition that disrupts thoughts and perceptions so profoundly that it can distort a person's sense of reality.

6 Nov 2025

Opioid receptors caught in motion offering clues for safer painkillers

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced "mew-opioid") receptors. What they didn't know - until now - was exactly what happens next.

5 Nov 2025

Common cholesterol drugs found to speed up PFAS removal from the body

Certain medicines can cause the environmental toxin PFAS to be eliminated from the body faster, according to a study at the University of Gothenburg.

4 Nov 2025

Do GLP-1 drugs cause cancer? New review says no, may even protect

A comprehensive review in The Journal of Clinical Investigation finds no overall link between GLP-1 receptor agonists and increased cancer risk, countering early safety concerns. Instead, evidence suggests possible protective effects for certain cancers, supported by metabolic and immune-modulating mechanisms.

4 Nov 2025

Pharmaceutical News

No, taking paracetamol while pregnant doesn’t cause autism or ADHD, major review finds

Evolocumab shows clear benefit in preventing first-time heart attacks and strokes

GLP-1 drugs linked to improved survival in colon cancer patients

Study warns of unsafe antiseizure drug use despite rising access

New drug combination gains Fast Track Designation for metastatic colorectal cancer

GLP-1 drugs beat metformin for weight control in teens with type 2 diabetes

Diabetes drugs semaglutide and tirzepatide show real-world heart benefits

PCSK9 inhibitor combined with a statin may help reduce LDL cholesterol after heart transplant

Weight loss drugs used by patients with high triglycerides do not increase pancreatitis risk

Diabetes drug blunts exercise-induced health improvements

Study reveals uneven access to abortion pill mifepristone in British Columbia

Machine learning advances human-centric drug toxicity prediction

UniSA launches pilot effort to make medicines safer for older Australians

Over-the-counter pain relievers outperform opioids after wisdom tooth extraction

New evidence reassures safety of acetaminophen use during pregnancy

Finerenone offers hope for kidney protection in patients with type 1 diabetes

Researchers identify patient response patterns to novel schizophrenia medication

Opioid receptors caught in motion offering clues for safer painkillers

Common cholesterol drugs found to speed up PFAS removal from the body

Do GLP-1 drugs cause cancer? New review says no, may even protect

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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