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GLP-1 drugs may offer cost-effective treatment for people with knee osteoarthritis and obesity

A new study led by investigators at Mass General Brigham finds that adding novel weight loss GLP-1 drugs semaglutide and tirzepatide to usual care represents a cost-effective treatment strategy for people with knee osteoarthritis and obesity, with tirzepatide providing greater health benefits at lower cost compared to semaglutide.

16 Sep 2025

Limited uptake of over-the-counter naloxone despite initial surge in sales

Sales of the overdose reversal medication naloxone increased after it was made available to the public without a prescription but then dipped quickly in the period following debut of over-the-counter sales, according to a new RAND study.

16 Sep 2025

Study: Half of adults without diabetes taking weight-loss drug discontinue treatment within a year

The new class of anti-obesity drugs, glucagon-like peptide-1 receptor agonists (GLP-1RAs), is proving remarkably effective at helping individuals lose weight.

15 Sep 2025

RSV vaccine slashes hospitalizations in older adults in real-world trial

A large, real-world randomized trial in Denmark found that the RSVpreF vaccine reduced RSV-related hospitalizations in adults aged 60 and over by over 80%. The vaccine also showed protection against broader respiratory illness with a favorable safety profile.

15 Sep 2025

Research reveals undisclosed active ingredients in retail mushroom products

"Magic mushroom" edibles sold at smoke shops and convenience stores are likely to contain no psilocybin but instead a range of undisclosed active ingredients, a study led by an Oregon State University College of Pharmacy scientist shows.

13 Sep 2025

Review highlights immunomodulatory and therapeutic effects of ginseng

Ginseng has long been used in traditional medicine to replenish Qi and address deficiency syndromes, often manifesting as fatigue and immune compromise.

13 Sep 2025

Under Trump, FDA seeks to abandon expert reviews of new drugs

FDA leaders under President Donald Trump are moving to abandon a decades-old policy of asking outside experts to review drug applications, a move critics say would shield the agency's decisions from public scrutiny.

12 Sep 2025

Driving performance unaffected in regular cannabis users after 48 hours of abstinence

Scientists from the Center for Medicinal Cannabis Research (CMCR) at the University of California San Diego School of Medicine found that, in the largest such study to date, frequent cannabis users did not display impairments in driving performance after at least 48 hours of abstinence.

11 Sep 2025

New technique used to conduct real-time measurement of boron in live tumor cells

A new technique has measured boron in individual cancer cells for the first time, enabling researchers to better understand how drugs act to kill tumors in some cancers.

10 Sep 2025

Bottlebrush particles deliver large range of chemotherapy drugs directly to tumor cells

Using tiny particles shaped like bottlebrushes, MIT chemists have found a way to deliver a large range of chemotherapy drugs directly to tumor cells.

10 Sep 2025

Popular weight-loss medications raise pregnancy safety concerns for women

Women taking popular weight-loss medications during their reproductive years may be unaware of associated risks to pregnancy and unborn babies, warn Flinders University researchers.

8 Sep 2025

Common diabetes drug metformin cuts long covid risk by 64 percent in UK study

A large UK-based retrospective cohort study found that initiating metformin within 90 days of COVID-19 diagnosis reduced the risk of Long COVID by 64% in overweight and obese adults. The findings suggest metformin may offer a low-cost preventive option pending confirmation from randomized trials.

8 Sep 2025

New class of antihypertensive medications may have both kidney- and cardio-protective benefits

Adding the novel medication baxdrostat to standard care may help manage high blood pressure and delay the progression of kidney disease in people with chronic kidney disease and uncontrolled high blood pressure , according to preliminary research presented at the American Heart Association's Hypertension Scientific Sessions 2025.

8 Sep 2025

Can an allergy spray help prevent COVID-19?

Researchers determine the efficacy and safety of azelastine nasal spray for preventing SARS-CoV-2 infection in healthy adults.

8 Sep 2025

WHO expands essential medicines lists with new cancer and diabetes treatments

Today, the World Health Organization (WHO) has released updated editions of its Model Lists of Essential Medicines (EML) and Essential Medicines for Children (EMLc), adding new treatments for various types of cancer and for diabetes with associated comorbidities such as obesity.

5 Sep 2025

Tirzepatide roll out reaches less than half of England’s GP practices

Less than half of England has access to tirzepatide (Mounjaro) through their GP, despite the NHS roll-out of the weight-loss jab officially starting over two months ago, an investigation by The BMJ has found.

5 Sep 2025

Semaglutide may one day be used to treat cocaine addiction

A drug already prescribed for type 2 diabetes and obesity may one day be used to treat cocaine addiction. In animal studies, researchers at the University of Gothenburg, Sweden, found that semaglutide reduced both cocaine use and relapse.

5 Sep 2025

As insurers struggle with GLP-1 drug costs, some seek to wean patients off

After losing 50 pounds on the injectable weight loss medication Zepbound, Kyra Wensley received a surprising letter from her pharmacy benefit manager in April.

4 Sep 2025

Weight loss medication semaglutide reduces cocaine seeking behavior in animal study

Scientists have found that the diabetes/weight loss drug Semaglutide, sold commercially under brand names like Ozempic and Wegovy, significantly reduces cocaine-seeking behaviour in rats.

4 Sep 2025

Single antibody causes a rare but dangerous reaction to widely-used blood thinner

Researchers at McMaster University have discovered that a rare but dangerous reaction to a widely used blood thinner is caused by a single antibody – overturning decades of medical misunderstanding and opening the door to more precise ways of diagnosing and treating this medical complication.

3 Sep 2025

Pharmaceutical News

GLP-1 drugs may offer cost-effective treatment for people with knee osteoarthritis and obesity

Limited uptake of over-the-counter naloxone despite initial surge in sales

Study: Half of adults without diabetes taking weight-loss drug discontinue treatment within a year

RSV vaccine slashes hospitalizations in older adults in real-world trial

Research reveals undisclosed active ingredients in retail mushroom products

Review highlights immunomodulatory and therapeutic effects of ginseng

Under Trump, FDA seeks to abandon expert reviews of new drugs

Driving performance unaffected in regular cannabis users after 48 hours of abstinence

New technique used to conduct real-time measurement of boron in live tumor cells

Bottlebrush particles deliver large range of chemotherapy drugs directly to tumor cells

Popular weight-loss medications raise pregnancy safety concerns for women

Common diabetes drug metformin cuts long covid risk by 64 percent in UK study

New class of antihypertensive medications may have both kidney- and cardio-protective benefits

Can an allergy spray help prevent COVID-19?

WHO expands essential medicines lists with new cancer and diabetes treatments

Tirzepatide roll out reaches less than half of England’s GP practices

Semaglutide may one day be used to treat cocaine addiction

As insurers struggle with GLP-1 drug costs, some seek to wean patients off

Weight loss medication semaglutide reduces cocaine seeking behavior in animal study

Single antibody causes a rare but dangerous reaction to widely-used blood thinner

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Empowering genomics research with cloud-based innovation

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