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WHO expands global network of trusted medical product regulators

The World Health Organization (WHO) has officially designated Health Canada, the Ministry of Health, Labour and Welfare/Pharmaceuticals and Medical Devices Agency (MHLW/PMDA) of Japan, and the Medicines and Healthcare products Regulatory Agency (MHRA) of the United Kingdom as WHO-Listed Authorities (WLAs), a status granted to national authorities that meet the highest international regulatory standards for medical products.

8 Aug 2025

Tracking counterfeit medicines through chemical fingerprints

Medicines have a unique chemical fingerprint, according to a new study from the University of Copenhagen. Researchers say this knowledge can be used to trace counterfeit or stolen medicine.

7 Aug 2025

Asthma drug found to prevent food allergy reactions in mice

A drug already FDA-approved for asthma was found to nearly eliminate life-threatening allergic reactions to food allergens in mice - a breakthrough that could lead to new protection for millions of people living with food allergies, reports a new Northwestern Medicine study.

7 Aug 2025

Deep learning model predicts adverse drug reactions from chemical structure

Adverse drug reactions (ADRs) are a significant cause of hospital admissions and treatment discontinuation worldwide. Conventional approaches often fail to detect rare or delayed effects of medicinal products.

7 Aug 2025

Flavonols found in foods can block drug resistance protein and boost medication absorption

Researchers identified specific flavonols that potently inhibit breast cancer resistance protein (BCRP), a key driver of drug resistance and poor oral drug absorption. The study found that these flavonols can reverse chemotherapy resistance in vitro and boost drug exposure in animal models, though clinical translation remains uncertain.

6 Aug 2025

RAND study highlights patterns of GLP-1 medication use and side effects

Nearly 12% of Americans have used GLP-1 drugs for weight loss, including about one-fifth of women aged 50 to 64, according to a new RAND report.

6 Aug 2025

Diabetes drug linked to lower risks of dementia and early death

New research in Diabetes, Obesity and Metabolism reveals that metformin, a medication traditionally prescribed to treat diabetes, is linked to lower risks of dementia and early death.

6 Aug 2025

Researchers question the historical basis of ancient psychedelic rituals

A new article in the peer-reviewed journal Psychedelic Medicine takes aim at one of the most influential, and controversial, narratives in comparative psychedelic culture: the idea that ancient Greek mystery rites at Eleusis were fueled by psychedelic drugs.

5 Aug 2025

Research offers hope for weight loss without gastrointestinal distress

Weight loss and diabetes drugs on the market often do not achieve long-term weight loss for patients. GLP-1 drugs target brain neurons that control appetite but frequently cause side effects.

5 Aug 2025

Starfish compound overcomes drug resistance in prostate cancer models

Researchers identified that triterpene glycosides from the starfish Solaster pacificus can kill drug-resistant prostate cancer cells in vitro by bypassing common resistance pathways. CuC1 showed synergy with existing chemotherapies, though with only moderate selectivity for cancer cells.

5 Aug 2025

Weight loss with ozempic may weaken muscles even when size remains stable

As use of the popular anti-diabetic and weight-loss drug Ozempic skyrockets, so have concerns about the medication's side effects.

5 Aug 2025

The Microsphere Summit is Back

Attend the 2025 Microsphere Summit to connect with leaders in drug delivery and manufacturing, focusing on particle size control and therapeutic advancements.

From Powder Systems 5 Aug 2025

New analgesic shows promise as opioid alternative

Opioids like morphine are widely used in medical practice due to their powerful pain-relieving effects. However, they carry the risk of serious adverse effects such as respiratory depression and drug dependence.

4 Aug 2025

HIV trial points to semaglutide as a new anti-aging contender

Once-weekly semaglutide significantly slowed epigenetic aging in adults with HIV-associated lipohypertrophy, as measured by multiple DNA methylation clocks in a randomized controlled trial. These exploratory findings suggest GLP-1 receptor agonists could impact biological aging but require further validation in broader populations.

4 Aug 2025

New drug combo outperforms Tamiflu in fighting deadliest flu strains

A surprising new drug combo—including a compound found in chocolate—has outperformed Tamiflu in fighting the flu, according to a study published in PNAS.

4 Aug 2025

Metformin’s blood sugar control starts in the brain, not just the liver, study finds

Low, clinically relevant doses of metformin lower blood glucose by inhibiting the Rap1 protein in specific neurons of the hypothalamus, revealing a brain-first mechanism. This action is essential for metformin’s effect at therapeutic doses and highlights new directions for diabetes treatment.

3 Aug 2025