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EMA designates allopurinol as first orphan drug for the treatment of Marfan syndrome

The European Medicines Agency (EMA) has designated allopurinol as the first orphan drug for the treatment of Marfan syndrome, a rare connective tissue disease which as no cure to date.

19 May 2025

Common anti-inflammatory drugs may aid virus spread

New research shows an unintended and unfortunate side effect of common drugs. They can simply help viruses spread.

19 May 2025

Repeated antibiotics in preterm infants linked to long-term lung problems

Repeated perinatal antibiotic exposure in very low-birth-weight preterm infants was associated with impaired lung function and a higher risk of asthma at early school age. The findings underscore the need for cautious antibiotic use and targeted respiratory health strategies in this high-risk group.

18 May 2025

Study reveals how acetaminophen may actually relieve pain

A new study from Indiana University scientists may aid the pharmaceutical industry in better understanding a popular over-the-counter pain reliever: Tylenol.

16 May 2025

Pharmacists stockpile most common drugs on chance of targeted Trump tariffs

In the dim basement of a Salt Lake City pharmacy, hundreds of amber-colored plastic pill bottles sit stacked in rows, one man's defensive wall in a tariff war.

16 May 2025

Peptide nanostructures block amyloid buildup and boost neuron survival in lab tests

Researchers developed trehalose-functionalized peptide amphiphiles (TPAs) that self-assemble into supramolecular nanostructures and demonstrated these TPAs can inhibit amyloid beta aggregation. In vitro, TPAs significantly improved survival of human neurons exposed to amyloid-induced neurotoxicity, suggesting therapeutic potential for neurodegenerative diseases.

15 May 2025

Ubrogepant relieves early migraine symptoms and may help prevent full-blown attacks

A phase 3 trial found that ubrogepant, given during the premonitory phase of migraine, improved common warning symptoms such as fatigue, light and sound sensitivity, and neck pain. These benefits were observed as early as one hour post-treatment, suggesting early intervention can reduce migraine burden.

15 May 2025

GLP-1 weight loss drugs leave users low on key nutrients, study finds

This study assessed nutrient intake in adults using GLP-1 receptor agonists (GLP-1RAs) and found widespread deficiencies in essential vitamins and minerals. Despite appetite suppression and weight loss benefits, most participants exceeded fat intake recommendations and failed to meet protein and micronutrient needs.

14 May 2025

Animal research reveals metabolic differences between tirzepatide and semaglutide

New animal research being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May), reveals distinct metabolic adjustments to tirzepatide and semaglutide treatment, with tirzepatide temporarily increasing energy expenditure and semaglutide initially reducing energy expenditure.

14 May 2025

Study shows cardiovascular benefits of GLP-1RAs in patients following bariatric surgery

Medications like semaglutide and liraglutide may help to reduce the risk for heart attacks, strokes, and other major adverse cardiovascular events (MACE) as well as death in adults with obesity and diabetes following bariatric surgery who did not achieve sufficient weight loss and diabetes control, according to new research being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain.

12 May 2025

GLP-1 drugs linked to significant BMI reduction in children with severe obesity

Children who are living with severe obesity are more likely to experience a clinically relevant change in BMI when GLP-1 agonist drugs form part of their treatment, new research being presented at year's European Congress on Obesity (ECO 2025) suggests.

12 May 2025

Tirzepatide outperforms semaglutide for weight loss in people without diabetes

A head-to-head trial found that tirzepatide led to significantly greater weight loss and waist reduction than semaglutide in adults with obesity but without diabetes. Over 72 weeks, tirzepatide helped more participants reach key weight loss milestones, with manageable side effects and strong metabolic benefits.

12 May 2025

Novel Alzheimer's therapy shows low risk of severe side effects

The Food and Drug Administration's approval in 2023 of lecanemab - a novel Alzheimer's therapy shown in clinical trials to modestly slow disease progression - was met with enthusiasm by many in the field as it represented the first medication of its kind able to influence the disease.

12 May 2025

Study reveals low rate of opioid addiction medications after overdose

Medications proven to effectively treat opioid addiction are rarely given after emergency department visits for overdose, and who gets them varies, sometimes greatly, depending on race, ethnicity or geography, University of Michigan researchers say.

12 May 2025

Probiotics show promise in supporting breast cancer patients during chemotherapy

Chemotherapy is one of the most popular ways to treat breast cancer. Even though it has proven to be effective, it also has downsides, such as a higher risk of side effects, as it doesn't only attack the cancer cells but can also affect normal cells.

12 May 2025

Australia faces critical medicine shortages amid global supply challenges

About 400 medicines are in short supply in Australia. Of these, about 30 are categorized as critical. These are ones with a life-threatening or serious impact on patients, and with no readily available substitutes.

12 May 2025

GLP-1RAs show added protection against cancer beyond weight reduction

New research being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May) and published in the journal eClinicalMedicine finds that first generation weight-loss medications like liraglutide and exenatide appear to show anti-cancer benefits beyond weight loss.

11 May 2025

Scientists link specific gene variants to post-vaccine myocarditis and pericarditis

A genome-wide association study in Sweden identified rare genetic variants near the SCAF11 and LRRC4C genes that may be linked to heart inflammation following COVID-19 mRNA vaccination. The findings shed light on potential biological pathways driving vaccine-associated myocarditis and pericarditis, particularly among younger individuals.

11 May 2025

New AI tool predicts viral mutations to help future-proof COVID vaccines

A novel AI-driven method helps scientists stay ahead of viral evolution by engineering synthetic spike proteins that anticipate future SARS-CoV-2 escape mutations, offering a powerful tool to test and strengthen next-generation vaccines.

11 May 2025

GLP-1 receptor agonists improve mood and metabolic health in adults with mental illness

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can lead to significant weight loss and improve blood sugar control in adults with severe mental illness, as well as having positive effects on mood, well-being, and quality of life in those both with and without mental illness, according to a systematic review of the available evidence being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May).

11 May 2025

Pharmaceutical News

EMA designates allopurinol as first orphan drug for the treatment of Marfan syndrome

Common anti-inflammatory drugs may aid virus spread

Repeated antibiotics in preterm infants linked to long-term lung problems

Study reveals how acetaminophen may actually relieve pain

Pharmacists stockpile most common drugs on chance of targeted Trump tariffs

Peptide nanostructures block amyloid buildup and boost neuron survival in lab tests

Ubrogepant relieves early migraine symptoms and may help prevent full-blown attacks

GLP-1 weight loss drugs leave users low on key nutrients, study finds

Animal research reveals metabolic differences between tirzepatide and semaglutide

Study shows cardiovascular benefits of GLP-1RAs in patients following bariatric surgery

GLP-1 drugs linked to significant BMI reduction in children with severe obesity

Tirzepatide outperforms semaglutide for weight loss in people without diabetes

Novel Alzheimer's therapy shows low risk of severe side effects

Study reveals low rate of opioid addiction medications after overdose

Probiotics show promise in supporting breast cancer patients during chemotherapy

Australia faces critical medicine shortages amid global supply challenges

GLP-1RAs show added protection against cancer beyond weight reduction

Scientists link specific gene variants to post-vaccine myocarditis and pericarditis

New AI tool predicts viral mutations to help future-proof COVID vaccines

GLP-1 receptor agonists improve mood and metabolic health in adults with mental illness

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