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Surge in syphilis cases leads some providers to ration penicillin

When Stephen Miller left his primary care practice to work in public health a little under two years ago, he said, he was shocked by how many cases of syphilis the clinic was treating.

1 Feb 2024

UH researcher aims to revolutionize treatment regimens for triple-negative breast cancer

A researcher at the University of Houston College of Pharmacy Drug Discovery Institute is working to revolutionize treatment regimens for triple-negative breast cancer (TNBC) by proving that nebivolol, an FDA-approved drug for high blood pressure, is effective in treating it.

31 Jan 2024

SGLT2 inhibitors linked to lower risk of kidney stones in patients with type 2 diabetes

Rates of kidney stones are on the rise in the United States and around the world. Type 2 diabetes is associated with increased risk of kidney stones, but some forms of treatment for this condition may also have the benefit of lowering risk of kidney stones.

31 Jan 2024

The FTC is attacking drugmakers’ ‘patent thickets’

The Federal Trade Commission has challenged the validity of over 100 drug product patents, focusing on devices used to deliver medicines, like inhalers and autoinjectors, in an effort to increase competition and potentially lower some prices.

31 Jan 2024

Ketamine therapy for mental health a ‘wild West’ for doctors and patients

In late 2022, Sarah Gutilla's treatment-resistant depression had grown so severe, she was actively contemplating suicide.

31 Jan 2024

Records show Publix opioid sales grew even as addiction crisis prompted other chains’ pullback

An executive at Teva Pharmaceuticals flagged Publix Super Markets in October 2015 after detecting what he called in an email "serious red flags" with the grocery chain's orders of powerful opioids.

29 Jan 2024

Puffed-up MOFs show improved performance as drug-delivery vehicles

The spongelike structure of metal organic frameworks (MOFs) allows these polymers to possibly carry and deliver a range of therapeutic compounds.

27 Jan 2024

Unbiased assessment of vamorolone for treating Duchenne muscular dystrophy

The drug vamorolone (Agamree) has been hailed as a promising new drug to treat Duchenne muscular dystrophy (DMD).

25 Jan 2024

Study confirms safety of COVID-19 vaccination during pregnancy for infant neurodevelopment

A large cohort study in "JAMA Pediatrics" found no significant differences in neurodevelopmental rates between infants exposed to COVID-19 vaccines in-utero and those who were not, affirming the safety of maternal COVID-19 vaccination.

24 Jan 2024

Balancing efficacy and safety: The challenges of mRNA drugs and vaccines in modern medicine

Researchers analyzed the toxicity concerns and advancements in mRNA therapeutics, focusing on their cellular toxicity, reactogenicity, and distribution, and discussed the challenges and benefits of mRNA research.

24 Jan 2024

Maternal COVID-19 vaccination equally benefits preterm and full-term babies

A study in JAMA Network Open reveals that maternal COVID-19 vaccination provides similar antibody levels in preterm and full-term infants' cord blood, with higher doses leading to increased antibodies.

24 Jan 2024

Calluna Pharma launches and announces EUR 75 million Series A financing to develop novel therapies for inflammatory and fibrotic diseases

Oxitope Pharma (Oxitope) and Arxx Therapeutics (Arxx), companies with a shared goal of leveraging the innate immune system to discover and develop disease modulating therapies, today announced their merger to form Calluna Pharma Inc. (Calluna).

From Calluna Pharma 24 Jan 2024

Blood pressure drug could help lower anxiety for kids and young adults with ASD

A new study at the University of Missouri's Thompson Center for Autism and Neurodevelopment found that propranolol, a medication that treats high blood pressure, can also help lower anxiety for kids and young adults with autism spectrum disorder (ASD).

23 Jan 2024

Monoclonal antibodies for Alzheimer's offer little benefit, raise safety concerns

Researchers performed a meta-analysis of randomized trial studies that compared the use of amyloid-reducing monoclonal antibodies (MABs) in patients with Alzheimer's dementia at a dose consistent with that used in Phase 3 or FDA approval trials with the use of a placebo.

22 Jan 2024

Tailoring a computerized decision support system to the ICU environment improves patient safety

A recent multicentre study led by Amsterdam UMC and conducted in nine Dutch Intensive Care Units (ICUs) has shown that tailoring a computerized decision support system (CDSS) to the ICU environment significantly reduced the number of high-risk drug combinations administered to ICU patients.

22 Jan 2024

Using AI to break the opioid addiction cycle

When Ben Brown, research assistant professor of chemistry, thinks about the opioid epidemic, he views the problem on a molecular level.

19 Jan 2024

Study analyzes the use of tissue-agnostic therapeutics in patients with primary brain tumors

Researchers from Miami Cancer Institute, part of Baptist Health South Florida, today published a study in Trends in Cancer that analyzes the use of tissue-agnostic therapeutics in patients with primary brain tumors (PBTs).

19 Jan 2024

The crucial need for ongoing COVID-19 booster vaccination in vulnerable populations

Researchers investigate the need for prioritizing COVID-19 booster vaccination.

19 Jan 2024

Exploring the impact of probiotics on preventing weight gain from psychiatric medication

Researchers discuss the effectiveness of probiotics and their use in reducing drug-induced weight loss.

19 Jan 2024

COVID-19 vaccines saved over 1.4 million lives across Europe, WHO study reveals

A study analyzing COVID-19 mortality and vaccination data in Europe from December 2020 to March 2023 found that vaccination efforts reduced the death toll by 57%, saving approximately 1.4 million lives, with the most significant impact observed in older individuals and during the Omicron variant surge.

17 Jan 2024

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Pharmaceutical News

Surge in syphilis cases leads some providers to ration penicillin

UH researcher aims to revolutionize treatment regimens for triple-negative breast cancer

SGLT2 inhibitors linked to lower risk of kidney stones in patients with type 2 diabetes

The FTC is attacking drugmakers’ ‘patent thickets’

Ketamine therapy for mental health a ‘wild West’ for doctors and patients

Records show Publix opioid sales grew even as addiction crisis prompted other chains’ pullback

Puffed-up MOFs show improved performance as drug-delivery vehicles

Unbiased assessment of vamorolone for treating Duchenne muscular dystrophy

Study confirms safety of COVID-19 vaccination during pregnancy for infant neurodevelopment

Balancing efficacy and safety: The challenges of mRNA drugs and vaccines in modern medicine

Maternal COVID-19 vaccination equally benefits preterm and full-term babies

Calluna Pharma launches and announces EUR 75 million Series A financing to develop novel therapies for inflammatory and fibrotic diseases

Blood pressure drug could help lower anxiety for kids and young adults with ASD

Monoclonal antibodies for Alzheimer's offer little benefit, raise safety concerns

Tailoring a computerized decision support system to the ICU environment improves patient safety

Using AI to break the opioid addiction cycle

Study analyzes the use of tissue-agnostic therapeutics in patients with primary brain tumors

The crucial need for ongoing COVID-19 booster vaccination in vulnerable populations

Exploring the impact of probiotics on preventing weight gain from psychiatric medication

COVID-19 vaccines saved over 1.4 million lives across Europe, WHO study reveals

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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