Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Long-term administration of IV iron benefits adults with heart failure and iron deficiency

Long-term treatment with iron administered intravenously improved symptoms and reduced recurrent hospitalizations among people with heart failure and iron deficiency, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Early use of ECMO devices to support adults with cardiogenic shock did not improve clinical outcomes

The immediate use of veno-arterial mechanical circulatory extracorporeal membrane oxygenation (ECMO) devices to support adults with rapidly deteriorating or severe cardiogenic shock was feasible but did not improve clinical outcomes compared to people who received early conservative therapy, according to late-breaking clinical trial results presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

SGLT-2 inhibitors reduce cardiovascular risk among patients with chronic kidney disease

SGLT-2 inhibitors, a type of diabetes medicine, decreased cardiovascular risk among adults with chronic kidney disease, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Novel gene editing therapy reduces circulating TTR protein levels in patients with ATTR amyloid cardiomyopathy

A single IV infusion of NTLA-2001, a novel CRISPR/Cas9-based gene editing therapy, significantly reduced circulating transthyretin (TTR) protein levels in patients with ATTR amyloid cardiomyopathy, a progressive and fatal cause of heart failure, according to late-breaking research presented today at the American Heart Association’s Scientific Sessions 2022.

7 Nov 2022

Researchers compare the risk of myocarditis between Pfizer and Moderna COVID-19 vaccines

Incidence of myocarditis, pericarditis or myopericarditis is two- to threefold higher after a second dose of the Moderna Spikevax COVID-19 vaccine when compared to the Pfizer BioNTech COVID-19 vaccine; however, overall cases of heart inflammation with either vaccine are very rare, according to a study in the Journal of the American College of Cardiology.

7 Nov 2022

National study sheds light on how to more effectively treat atrial fibrillation

A national study led by UBC researchers at the Centre for Cardiovascular Innovation is shedding light on how to more effectively treat atrial fibrillation (AF) – a common heart rhythm problem associated with increased risk of stroke and heart failure.

7 Nov 2022

High-intensity treatment strategy for heart failure reduces the risk of death or hospital readmission

Ramping up medication doses quickly after being hospitalized for acute heart failure resulted in a lower risk of dying or being readmitted for heart failure within the first six months after discharge, compared to usual care, according to a featured science research presentation today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

New one-stop guideline takes a 360-degree approach to managing heart disease in Canadians

A new one-stop guideline takes a 360-degree approach to managing heart disease in Canadian patients, with 83 recommendations in one easy-to-use reference. The guideline is published in CMAJ (Canadian Medical Association Journal).

7 Nov 2022

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Researchers reviewed technology advancements that will unlock the promise of biologically targeted messenger ribonucleic acid (mRNA) therapeutics beyond vaccines.

7 Nov 2022

Cannabis, cocaine, methamphetamine, and opiates increase risk of atrial fibrillation

A recent study published in the European Heart Journal reveals that using illicit drugs can increase atrial fibrillation risk.

6 Nov 2022

Study examines temporal effects of pre-existing CKD, other medical conditions on COVID-19 outcomes

Individuals with chronic kidney disease (CKD) are vulnerable to developing severe forms of COVID-19, and acute kidney injury is a common complication of COVID-19.

6 Nov 2022

Researchers compare the impact of conservative kidney disease management vs. dialysis on hospitalization outcomes

For some individuals with advanced kidney disease, dialysis may not be the optimal treatment strategy for their condition, and these patients may be better served with conservative non-dialytic management that focuses on quality of life and symptom control.

6 Nov 2022

Two heart failure therapies prove to be nearly identical in reducing death

In a head-to-head comparison of two so-called 'water pills' that keep fluid from building up in patients with heart failure, the therapies proved nearly identical in reducing deaths, according to a large study led by Duke Health researchers.

6 Nov 2022

Experts estimate the prevalence of breast cancer survivors in Canada

It was the information she couldn't find that led Amy Kirkham, an assistant professor in the University of Toronto's Faculty of Kinesiology & Physical Education (KPE), to her latest discovery.

3 Nov 2022

Study identifies a root cause of chronic heart failure following a heart attack

A multi-institution study led by Rohan Dharmakumar, PhD, of Indiana University School of Medicine, has identified that iron drives the formation of fatty tissue in the heart and leads to chronic heart failure in about fifty percent of heart attack survivors.

1 Nov 2022

COVID-19 positive hearts may be safe for transplantation

A recent study soon to be presented at the American Heart Association (AHA) Scientific Sessions 2022* suggests that hearts from coronavirus disease 2019 (COVID-19)-positive (COVID-19+) donors may be safe for transplantation.

1 Nov 2022

New red blood cell destruction model based on dissipative particle dynamics within a high shear flow

Many medical devices for treating heart failure generate nonphysiological shear flow. This can trigger the destruction of red blood cells after implantation of ventricular assist devices (VADs), artificial heart valves, vascular stents, or interventional thrombectomy devices.

1 Nov 2022

Heart Failure News and Research

Further Reading

Long-term administration of IV iron benefits adults with heart failure and iron deficiency

Early use of ECMO devices to support adults with cardiogenic shock did not improve clinical outcomes

SGLT-2 inhibitors reduce cardiovascular risk among patients with chronic kidney disease

Novel gene editing therapy reduces circulating TTR protein levels in patients with ATTR amyloid cardiomyopathy

Researchers compare the risk of myocarditis between Pfizer and Moderna COVID-19 vaccines

National study sheds light on how to more effectively treat atrial fibrillation

High-intensity treatment strategy for heart failure reduces the risk of death or hospital readmission

New one-stop guideline takes a 360-degree approach to managing heart disease in Canadians

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Cannabis, cocaine, methamphetamine, and opiates increase risk of atrial fibrillation

Study examines temporal effects of pre-existing CKD, other medical conditions on COVID-19 outcomes

Researchers compare the impact of conservative kidney disease management vs. dialysis on hospitalization outcomes

Two heart failure therapies prove to be nearly identical in reducing death

Experts estimate the prevalence of breast cancer survivors in Canada

Study identifies a root cause of chronic heart failure following a heart attack

COVID-19 positive hearts may be safe for transplantation

New red blood cell destruction model based on dissipative particle dynamics within a high shear flow

New analysis on the risk for myocarditis or pericarditis after mRNA COVID-19 vaccination

Medicare fines for high hospital readmissions drop, but 2,300 facilities are still penalized

COVID-19-positive donor hearts appear to be safe for transplantation

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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