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Researchers identify alterations in proteins responsible for RNA splicing in Alzheimer's

Researchers at Emory University School of Medicine's Alzheimer's Disease Research Center have identified a previously unrecognized type of pathology in the brains of patients with Alzheimer's disease.

11 Sep 2013

Researchers discover inherited gene mutation linked to childhood leukemia

Researchers have discovered the first inherited gene mutation linked exclusively to acute lymphoblastic leukemia occurring in multiple relatives in individual families. The discovery of the PAX5 gene mutation was led by St. Jude Children's Research Hospital and others. The work appears in the current advance online edition of the scientific journal Nature Genetics.

11 Sep 2013

Interferon-alpha 2b and ribavirin treatment may be effective for MERS-CoV infection

Treatment with two common drugs reduced viral replication and lung damage when given to monkeys infected with the virus that causes Middle East Respiratory Syndrome. The condition is deadly pneumonia that has killed more than 100 people, primarily in the Middle East.

10 Sep 2013

Chemists Find New Way To Put The Brakes On Cancer

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10 Sep 2013

Biologists identify two pathways via which chromosomes are rearranged

Biologists reported today in Nature that they have identified two pathways through which chromosomes are rearranged in mammalian cells. These types of changes are associated with some cancers and inherited disorders in people.

10 Sep 2013

Scientists develop strain of MERS-CoV that can be used as vaccine against disease

Scientists have developed a strain of the Middle East respiratory syndrome coronavirus (MERS-CoV) that could be used as a vaccine against the disease, according to a study to be published in mBio-, the online open-access journal of the American Society for Microbiology.

10 Sep 2013

Little STING could go long way in avoiding arthritis, type 1 diabetes, report researchers

A little STING could go a long way in helping treat or even avoid autoimmune diseases such as arthritis, type 1 diabetes and multiple sclerosis, researchers report.

10 Sep 2013

One-time treatment slows onset and progression of ALS, study finds

Studies of a therapy designed to treat amyotrophic lateral sclerosis suggest that the treatment dramatically slows onset and progression of the deadly disease, one of the most common neuromuscular disorders in the world.

10 Sep 2013

Scientists identify RNA regulator that plays critical role in proper functioning of hESCs

Scientists at A*STAR's Genome Institute of Singapore, in collaboration with their counterparts from Canada, Hong Kong and US, have discovered a protein mediator SON plays a critical role in the health and proper functioning of human embryonic stem cells. This finding was reported on 8th September 2013 in the advanced online issue of the prestigious science journal Nature Cell Biology.

10 Sep 2013

Researchers discover why multiple myeloma persistently escapes cure

Clinical researchers at Princess Margaret Cancer Centre have discovered why multiple myeloma, an incurable cancer of the bone marrow, persistently escapes cure by an initially effective treatment that can keep the disease at bay for up to several years.

10 Sep 2013

Researchers identify genetic link specific to risk of childhood leukemia

For the first time, a genetic link specific to risk of childhood leukemia has been identified, according to a team of researchers from Memorial Sloan-Kettering Cancer Center, St. Jude Children's Research Hospital, University of Washington, and other institutions. The discovery was reported online today in the journal Nature Genetics.

10 Sep 2013

Scientists find link between early-onset Parkinson's and 22q11.2 deletion syndrome

Scientists at the Centre for Addiction and Mental Health (CAMH) and University Health Network (UHN) have found a new link between early-onset Parkinson's disease and a piece of DNA missing from chromosome 22. The findings help shed new light on the molecular changes that lead to Parkinson's disease.

10 Sep 2013

Penn’s ITMAT symposium addresses topics of direct relevance to translational science

The Institute for Translational Medicine and Therapeutics' 7th Annual International Symposium (ITMAT) symposium, Harnessing the Paradox: Personalization and the Science of Scale, to be held in October 2013, will address topics of direct relevance to translational science.

7 Sep 2013

Locus coeruleus plays major role in learning, memory and other cognitive functions

Death of neurons in the dorsal raphe nucleus and locus coeruleus is a pathological characteristic of the disease. Previous studies concerning the pathological characteristic of Alzheimer's disease mainly focus on learning and memory-related hippocampus, and less attention has been paid to the locus coeruleus.

6 Sep 2013

Researchers explore distinctions between natural sleep and anesthetic unconsciousness

Falling asleep in your bed at night and being "put to sleep" under general anesthesia - as well as waking up in the morning or coming out of anesthesia - aren't quite the same thing, yet they share some important similarities. Max Kelz, MD, PhD, assistant professor of Anesthesiology and Critical Care at the Perelman School of Medicine at the University of Pennsylvania, along with colleagues from Penn, UCSD, Howard Hughes Medical Institute, and Thomas Jefferson University, explored the distinctions between anesthetic unconsciousness and sleep by manipulating the genetic pathways known to be involved in natural sleep and studying the resulting effects on anesthetic states.

6 Sep 2013

Bioinformatics researchers investigate functional diversity of proteins

No two human beings are the same. Although we all possess the same genes, our genetic code varies in many places. And since genes provide the blueprint for all proteins, these variants usually result in numerous differences in protein function. But what impact does this diversity have? Bioinformatics researchers at Rutgers University and the Technische Universitaet Muenchen have investigated how protein function is affected by changes at the DNA level.

6 Sep 2013

Researchers translate new technology to better study behaviors and cellular function to fruit flies

A team of researchers led by Charles D. Nichols, PhD, Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, has successfully translated a new technology to better study behaviors and cellular function to fruit flies.

6 Sep 2013

Researchers develop method for purifying cardiac muscle cells using molecular beacons

Pure cardiac muscle cells, ready to transplant into a patient affected by heart disease. That's a goal for many cardiology researchers working with stem cells. Having a pure population of cardiac muscle cells is essential for avoiding tumor formation after transplantation, but has been technically challenging.

6 Sep 2013

UCSF to receive grant to study gene sequencing aimed at detecting disorders in newborns

UC San Francisco will receive $4.5 million over the next five years for a pilot project to assess whether large-scale gene sequencing aimed at detecting disorders and conditions can and should become a routine part of newborn testing.

6 Sep 2013

International team of scientists discover new disease related to inability to process Vitamin B12

An international team of scientists, including University of Colorado School of Medicine and Children's Hospital Colorado researchers, has discovered a new disease related to an inability to process Vitamin B12.

6 Sep 2013

Genes News and Research

Researchers identify alterations in proteins responsible for RNA splicing in Alzheimer's

Researchers discover inherited gene mutation linked to childhood leukemia

Interferon-alpha 2b and ribavirin treatment may be effective for MERS-CoV infection

Chemists Find New Way To Put The Brakes On Cancer

Biologists identify two pathways via which chromosomes are rearranged

Scientists develop strain of MERS-CoV that can be used as vaccine against disease

Little STING could go long way in avoiding arthritis, type 1 diabetes, report researchers

One-time treatment slows onset and progression of ALS, study finds

Scientists identify RNA regulator that plays critical role in proper functioning of hESCs

Researchers discover why multiple myeloma persistently escapes cure

Researchers identify genetic link specific to risk of childhood leukemia

Scientists find link between early-onset Parkinson's and 22q11.2 deletion syndrome

Penn’s ITMAT symposium addresses topics of direct relevance to translational science

Locus coeruleus plays major role in learning, memory and other cognitive functions

Researchers explore distinctions between natural sleep and anesthetic unconsciousness

Bioinformatics researchers investigate functional diversity of proteins

Researchers translate new technology to better study behaviors and cellular function to fruit flies

Researchers develop method for purifying cardiac muscle cells using molecular beacons

UCSF to receive grant to study gene sequencing aimed at detecting disorders in newborns

International team of scientists discover new disease related to inability to process Vitamin B12

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