Genes News and Research

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MDI Biological Laboratory discover mechanisms underlying regeneration of heart tissue

The MDI Biological Laboratory has announced new discoveries about the mechanisms underlying the regeneration of heart tissue by Assistant Professor Voot P. Yin, Ph.D., which raise hope that drugs can be identified to help the body grow muscle cells and remove scar tissue, important steps in the regeneration of heart tissue.

10 Mar 2016

TSRI researchers uncover new molecular mechanism underlying neurodegenerative diseases

A new study led by scientists at The Scripps Research Institute suggests that cells construct protein "clumps" to protect against neurodegenerative diseases such as amyotrophic lateral sclerosis, a.k.a. ALS or Lou Gehrig's disease.

10 Mar 2016

Discovery may provide potential target for new therapies to treat bipolar disorder

Bipolar disorder, which affects nearly eight million Americans, takes a toll not only on patients, but also on their families and communities.

10 Mar 2016

Startling lack of resistance genes discovered in intensively-farmed beef

In the first study to track antibiotic resistance in intensively-farmed beef, scientists discovered a "startling" lack of resistance genes in meat.Meanwhile, in soil and faeces samples from cattle pens they found genes resistant to a powerful "last resort" class of antibiotics called carpabemens that aren't used in the livestock industry. These genes may have jumped from humans or companion animals to livestock, or could even be present at low levels in the wider environment.

9 Mar 2016

Bonn scientists identify immune factor partially responsible for chronic viral infection

Many viral diseases tend to become chronic - including infections with the HI virus. In persons affected, the immune response is not sufficient to eliminate the virus permanently.

8 Mar 2016

ACGT awards new research grants to take researchers to next level in cancer treatment

Alliance for Cancer Gene Therapy, the nation's only nonprofit dedicated exclusively to cell and gene therapies for cancer, is delighted to announce the recipients of its 2016 ACGT Young Investigator Grants.

8 Mar 2016

Specialized tests can help dermatologists provide individualized care for melanoma patients

Melanoma rates in the United States have doubled over the past two decades.1 Fortunately for patients, this increase in melanoma incidence has been accompanied by the development of more effective tools for diagnosis and treatment, including genetic and molecular testing.

7 Mar 2016

Blood test may spot first signs of skin cancer relapse

A BLOOD test may be able to sound early warning bells that patients with advanced melanoma skin cancer are relapsing, according to a study published in the journal Cancer Discovery today (Monday).

7 Mar 2016

Absence of PEMT enzyme leads to development of fatty liver disease and tumours in thin patients

Researchers observe protection against obesity and insulin resistance but at the cost of prominent fatty liver disease in mice lacking the PEMT enzyme and patients with low levels of PEMT.

7 Mar 2016

Johns Hopkins Greenberg Bladder Cancer Institute awards grants for 10 bladder cancer research projects

A study of obesity and related metabolic changes on bladder cancer incidence and deaths, and a plan to use stem cells to grow novel urinary tubes are among 10 research projects awarded funding by the Johns Hopkins Greenberg Bladder Cancer Institute.

7 Mar 2016

Researchers identify how Zika virus may cause microcephaly in fetuses

Working with lab-grown human stem cells, a team of researchers suspect they have discovered how the Zika virus probably causes microcephaly in fetuses. The virus selectively infects cells that form the brain's cortex, or outer layer, making them more likely to die and less likely to divide normally and make new brain cells.

7 Mar 2016

Antibiotic resistance: A serious threat to human health

The World Health Organization has identified antibiotic resistance as a serious threat to human health across the world. The Journal of Environmental Quality recently published a special section titled "Antibiotics in Agroecosystems" to address the science of this important topic.

4 Mar 2016

IOM report elucidates state of ovarian cancer incidence, treatment and research

Ovarian cancer, one of the deadliest malignancies, is actually a constellation of different cancers that may originate in other organs and should not be treated as a single disease, concludes a new congressionally mandated report on the state of ovarian cancer incidence, treatment and research. The report, published by the Institute of Medicine of the National Academies of Sciences, Engineering, and Medicine, also highlights persistent serious disparities in delivery of care across different groups of women in the U.S., and suggests promising areas for further research.

4 Mar 2016

P53 genetic variant heavily implicated in metabolism, new research finds

The study may also provide an evolutionary explanation for differences in populations living farther away from the Equator. Human ancestors may have undergone this change in R72 to promote energy storage in cold climates and during times of famine. However, in modern society, the need for this type of variant in our genes is unnecessary, leading instead to increased risk for obesity and type 2 diabetes. Obesity is also a risk factor for certain types of cancer, so these findings may also explain why the R72 variant of p53 might predispose certain people to cancer.

4 Mar 2016

Cardiac reprogramming could shrink heart scar tissue, improve patients' heart function

Patients with heart failure often have a buildup of scar tissue that leads to a gradual loss of heart function. In a new study published today in the journal Cell Stem Cell, researchers from the University of North Carolina School of Medicine report significant progress toward a novel approach that could shrink the amount of heart scar tissue while replenishing the supply of healthy heart muscle.

4 Mar 2016

Healthy cells actively collaborate with tumours to promote growth of new blood vessels

Healthy cells actively collaborate with tumours by creating a mesh of collagen that encourages cancer cells to build new blood vessels, a new study shows.

4 Mar 2016

Study highlights use of 10x Genomics' GemCode technology platform for genomic analysis

10x Genomics, a company focused on improving and broadening the application of genomic information across healthcare and other industries, today announced the publication of a study that was enabled by the company's GemCode™ technology platform, a powerful new approach that allows researchers to discover previously inaccessible genomic information.

From 10x Genomics, Inc. 4 Mar 2016

Study provides critical insight into Warburg effect

PGK1, a glycolytic enzyme, has been found to play a role in coordinating cellular processes crucial to cancer metabolism and brain tumor formation, according to results published in today's online issue of Molecular Cell. The findings may lay the groundwork for improved approaches to diagnosis and treatment of glioblastoma and other cancers.

4 Mar 2016

MSU scientists identify new kind of stem cell that could advance regenerative medicine

Scientists at Michigan State University have discovered a new kind of stem cell, one that could lead to advances in regenerative medicine as well as offer new ways to study birth defects and other reproductive problems.

4 Mar 2016

Modified protein appears to reverse liver fibrosis, cirrhosis in rats

A protein modified to increase the amount of time it circulates in the bloodstream appears to reverse liver fibrosis and cirrhosis in rats, according to results of a study led by Johns Hopkins researchers.

3 Mar 2016

Genes News and Research

MDI Biological Laboratory discover mechanisms underlying regeneration of heart tissue

TSRI researchers uncover new molecular mechanism underlying neurodegenerative diseases

Discovery may provide potential target for new therapies to treat bipolar disorder

Startling lack of resistance genes discovered in intensively-farmed beef

Bonn scientists identify immune factor partially responsible for chronic viral infection

ACGT awards new research grants to take researchers to next level in cancer treatment

Specialized tests can help dermatologists provide individualized care for melanoma patients

Blood test may spot first signs of skin cancer relapse

Absence of PEMT enzyme leads to development of fatty liver disease and tumours in thin patients

Johns Hopkins Greenberg Bladder Cancer Institute awards grants for 10 bladder cancer research projects

Researchers identify how Zika virus may cause microcephaly in fetuses

Antibiotic resistance: A serious threat to human health

IOM report elucidates state of ovarian cancer incidence, treatment and research

P53 genetic variant heavily implicated in metabolism, new research finds

Cardiac reprogramming could shrink heart scar tissue, improve patients' heart function

Healthy cells actively collaborate with tumours to promote growth of new blood vessels

Study highlights use of 10x Genomics' GemCode technology platform for genomic analysis

Study provides critical insight into Warburg effect

MSU scientists identify new kind of stem cell that could advance regenerative medicine

Modified protein appears to reverse liver fibrosis, cirrhosis in rats

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