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PsiOxus initiates ColoAd1 phase I/II trial in metastatic solid tumours

PsiOxus Therapeutics, Ltd. has treated the first patient in its phase I/II clinical trial of ColoAd1for the treatment of metastatic solid tumours.

26 Sep 2012

High concentrations of inhaled oxygen during and after cancer surgery may increase risk of death

Patients given high concentrations of inhaled oxygen during and after cancer surgery may be at higher long-term risk of death, according to a report in the October issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

26 Sep 2012

Flow cytometry isolates stem cells from brain tumors

A new video protocol in Journal of Visualized Experiments (JoVE) details an assay to identify brain tumor initiating stem cells from primary brain tumors. Through flow cytometry, scientists separate stem cells from the rest of the tumor, allowing quick and efficient analysis of target cells. This approach has been effectively used to identify similar stem cells in leukemia patients.

26 Sep 2012

Differences in viral illness patterns play a role in asthma development in urban, suburban children

Children living in low-income urban areas appear especially prone to developing asthma, possibly related to infections they acquire early in life. In a new study in The Journal of Infectious Diseases, available online, researchers from the University of Wisconsin in Madison investigated viral respiratory illnesses and their possible role in the development of asthma in urban versus suburban babies.

26 Sep 2012

Regular mammography screening can help narrow racial gaps in breast cancer outcomes

Regular mammography screening can help narrow the breast cancer gap between black and white women, according to a retrospective study published in Breast Cancer Research and Treatment in August.

26 Sep 2012

Kidney disease linked with risk of death and ESRD even in patients without hypertension or diabetes

Two new studies from the Johns Hopkins Bloomberg School of Public Health and the Chronic Kidney Disease Prognosis Consortium found that the presence of chronic kidney disease itself can be a strong indicator of the risk of death and end-stage renal disease (ESRD) even in patients without hypertension or diabetes.

26 Sep 2012

Warfarin therapy should not be stopped completely after GI bleeding

The decision to not resume warfarin therapy following a gastrointestinal bleeding event is linked to an increased risk for thrombosis and mortality, researchers suggest.

25 Sep 2012

Three-factor tool could be all you need to assess surgery risk

A simple tool involving less than six variables to measure surgical outcomes could be all that is needed to predict inpatient mortality, show US study results.

25 Sep 2012

Persistence pays out exercise benefits in heart failure

Health benefits derived from regular exercise accumulate over the long term, shows a 10-year study in patients with heart failure.

25 Sep 2012

Pervenio Lung RS from Life Technologies

Life Technologies Corporation today announced the launch of Pervenio Lung RS. First-of-its-kind, the molecular test has been documented to reliably identify early stage lung cancer patients who are at high risk for mortality following surgery. It also fulfills an unmet need for prognostic information to guide preventative treatment and improve disease management.

25 Sep 2012

Researchers discover genetics secrets of ovarian cancer tumors

A new discovery that sheds light on the genetic make up of ovarian cancer cells could explain why some women survive longer than others with this deadly disease.

25 Sep 2012

Comprehensive prenatal care can decrease rates of low birth weights

Comprehensive prenatal care can decrease the rate of low birth weights, according to a study led by Dr. Yasmin Neggers, a University of Alabama researcher and professor of human nutrition and hospitality management.

25 Sep 2012

State roundup: Anthem dumps Cedars-Sinai, UCLA docs

Two of the most prestigious names in Southern California health care -- Cedars-Sinai and UCLA -- are getting shut out of a major insurance plan for being too expensive. In a bold cost-cutting move, Anthem Blue Cross has eliminated doctors affiliated with the hospitals from a health plan offered to about 60,000 employees and dependents at the cash-strapped city of Los Angeles.

25 Sep 2012

Sudanese refugee camps see improvement in water, food provisions, but concerns remain over disease threats, overcrowding

"Aid agencies say water and food provision has improved in four camps housing more than 105,000 refugees from Sudan's Blue Nile State, but flooding, disease and an influx of additional refugees pose new threats," IRIN reports, noting, "Sudan's government forces and rebels have been fighting in Blue Nile State since September 2011, sending refugees south."

25 Sep 2012

PPI use linked with risk for infection in decompensated cirrhosis

Proton-pump inhibitors are associated with an increased risk for serious infections in patients with decompensated cirrhosis, research shows.

24 Sep 2012

Age at onset influences juvenile dermatomyositis course

Children diagnosed with juvenile dermatomyositis at age 3 years or earlier have milder symptoms than patients with later onset, research suggests.

24 Sep 2012

More money, focus needed to reach maternal, child health MDGs

Though the global community has "made incredible inroads" on the Millennium Development Goals (MDGs), "the majority of developing countries are still expected to fall short of the MDG targets for reducing maternal and child mortality by 2015," Carole Presern, director of the Partnership for Maternal, Newborn & Child Health (PMNCH), writes in the Huffington Post's "Global Motherhood" blog.

24 Sep 2012

Boehringer Ingelheim completes enrollment in nintedanib Phase III trials for IPF

Boehringer Ingelheim is pleased to announce the last patients have been randomised into the Phase III sister trials assessing the efficacy and safety of nintedanib (150 mg twice daily) in patients with idiopathic pulmonary fibrosis (IPF).

24 Sep 2012

Suicide now the leading cause of injury mortality in the U.S.

A published study by researchers from the West Virginia University School of Public Health and Injury Control Research Center found that suicide has now passed motor vehicle traffic crashes as the leading cause of injury deaths in the United States. Additionally, the disease rate has been declining while the injury rate has been rising.

24 Sep 2012

London-led research looks at data that shows decline in post-anaesthetic deaths

A team of researchers led by London's Dr. Daniel Bainbridge have compiled data from 87 studies worldwide that shows post-anaesthetic deaths have declined as much as 90 percent since before the 1970s. During the same period, the risk of dying from any cause within 48 hours of surgery has decreased by 88 percent. The study covered outcomes in both developed and developing countries, with the findings published in the current issue of the high-profile journal The Lancet.

24 Sep 2012