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New drug targets for Huntington's disease

Research funded by the Wellcome Trust has provided a number of promising new drug targets for Huntington's disease, a neurodegenerative disease.

25 Mar 2008

Research finds genes and processes that may underlie what makes some people more susceptible to Parkinson's disease

Better understanding of Parkinson's disease onset during aging is important for improving diagnostics and developing strategies for therapeutic intervention.

24 Mar 2008

Brains are hardwired to act according to the Golden Rule

Wesley Autrey, a black construction worker, a Navy veteran and 55-year-old father of two, didn't know the young man standing beside him.

24 Mar 2008

Researchers may have found test for depression

Researchers from the University of Illinois at Chicago College of Medicine have discovered that a change in the location of a protein in the brain could serve as a biomarker for depression, allowing a simple, rapid, laboratory test to identify patients with depression and to determine whether a particular antidepressant therapy will provide a successful response.

12 Mar 2008

Short-term stress impairs brain-cell communication

Short-term stress lasting as little as a few hours can impair brain-cell communication in areas associated with learning and memory, University of California, Irvine researchers have found.

12 Mar 2008

New discovery could change future diagnosis and therapy of depression

12 Mar 2008

Post brain injury: New nerve cells originate from neural stem cells

Most cells in the human brain are not nerve cells, but supporting cells (glial cells).

12 Mar 2008

Cell therapy for rejuvenating aged brain by injection of human umbilical cord blood

When human umbilical cord blood cells (UCBC) were injected into aged laboratory animals, researchers at the University of South Florida (USF) found improvements in the microenvironment of the hippocampus region of the animals' brains and a subsequent rejuvenation of neural stem/progenitor cells.

11 Mar 2008

Paradoxical Alzheimer's finding may provide better understanding of memory loss

Do you remember the seventh song that played on your radio on the way to work yesterday?

10 Mar 2008

Neural progenitor cells as reservoirs for HIV in the brain

Impaired brain function is a prominent and still unsolved problem in AIDS.

6 Mar 2008

Large-scale study of traumatic brain injury

In a rare, large-scale study of traumatic brain injury (TBI) patients who span the full range of severity from mild to moderate and severe, Canadian researchers have found that the more severe the injury, the greater the loss of brain tissue, particularly white matter.

4 Mar 2008

Mouse model tightly matches pediatric tumor syndrome, will speed drug hunt

Frustrated by the slow pace of new drug development for a condition that causes pediatric brain tumors, a neurologist at Washington University School of Medicine in St. Louis decided to try to fine-tune the animal models used to test new drugs.

3 Mar 2008

New view of human brainstem

A team of scientists from Princeton University has devised a new experimental technique that produces some of the best functional images ever taken of the human brainstem, the most primitive area of the brain.

28 Feb 2008

New insight into the fundamentals of Parkinson's disease

A single change in a protein may play a role in whether someone develops Parkinson's disease, say University of Florida Genetics Institute researchers writing in a recent issue of the Proceedings of the National Academy of Sciences.

27 Feb 2008

Tumor-killing virus selectively targets diseased brain cells

New findings show that a specialized virus with the ability to reproduce its tumor-killing genes can selectively target tumors in the brains of mice and eliminate them.

20 Feb 2008

Many Aussies would take a test for dementia

According to a new report, by the year 2050 as many as 730,000 Australians will be suffering from some form of dementia and almost three quarters of Australians say if such a test existed to show if they were going to develop some form of dementia, they would take it.

18 Feb 2008

Some cases of autism may be traced to the immune system of mothers during pregnancy

New research from the UC Davis M.I.N.D. Institute and Center for Children's Environmental Health has found that antibodies in the blood of mothers of children with autism bind to fetal brain cells, potentially interrupting healthy brain development.

12 Feb 2008

Prion infection of neurons increases the free cholesterol content in cell membranes

A new study published in the online open access journal BMC Biology suggests that disturbances in membrane cholesterol may be the mechanism by which prions cause neurodegeneration and could point to a role for cholesterol in other neurodegenerative diseases.

12 Feb 2008

Prenatal exposure to maternal antibodies linked to autistic behaviors in offspring

New research from the UC Davis M.I.N.D. Institute shows that an interaction between fetal brain cells and maternal antibodies could be linked with the repetitive behavior - also called stereotypies - that is characteristic of autism.

12 Feb 2008

VEGF-B helps nerve cells cheat death without unwanted side effects

The prototypical member of the VEGF family of proteins, VEGF, has recently been shown to protect cells in the nervous system from death and degeneration.

8 Feb 2008