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Nottingham animal scientist receives 'Marshall Medal' for fertility and reproduction study

A leading University of Nottingham animal scientist has been awarded one of the most prestigious medals in the field of animal reproductive biology.

3 Aug 2011

Federal judge upholds Obama rule on stem cell research

A U.S. judge Wednesday upheld the government rules that allow federal funding of human embryonic stem cell research that might lead to cures for deadly diseases affecting millions of Americans.

29 Jul 2011

Introducing maspin protein into tumor nucleus can stop growth and spread of cancer

According to the Canadian Cancer Society, one in four Canadians will die of cancer. This year alone, the disease will kill an estimated 75,000 people. With incidence rates on the rise, more cancer patients are facing grave prognoses.

29 Jul 2011

Mitochondrial genome undergoes random reorganisation during reprogramming

Induced pluripotent stem cells (iPS cells) are truly talented multi-taskers. They can reproduce almost all cell types and thus offer great hope in the fight against diseases like Alzheimer's and Parkinson's. However, it would appear that their use is not entirely without risk: during the reprogramming of body cells into iPS cells, disease-causing mutations can creep into the genetic material.

28 Jul 2011

Dilemma of single vs. double embryo transfers

Elsevier announced the publication of several commentaries in the scientific journal Reproductive BioMedicine Online on the subject of how many embryos it is safe and proper to place in a uterus, and how best to regulate this decision. It is a dilemma faced by all patients anxiously caught between no pregnancies at all or facing the prospect of twins or triplets. In this difficult place it is often all too easy to think that the latter option must be the best. But is it?

28 Jul 2011

Invadopodia could help survival of cancer cells

Delicate, threadlike protrusions used by cancer cells when they invade other tissues in the body could also help them escape control mechanisms supposed to eliminate them, a research group led by led by Bradley Davidson in the University of Arizona's department of molecular and cellular biology reports in Nature Cell Biology.

28 Jul 2011

U.S. Judge approves federal funding for embryonic research

Federal funding of human embryonic stem cell (hESC) research is now legal in the United States. Chief judge of the US District Court for the District of Columbia Royce Lamberth has ruled on the case Sherley et al. v. Sebelius, in favor of hESC research. This overturns an existing law that prohibits the government from funding research that destroys the embryo.

27 Jul 2011

Loss of critical male development gene causes male cells to become female

University of Minnesota Medical School and College of Biological Sciences researchers have made a key discovery showing that male sex must be maintained throughout life.

21 Jul 2011

Scientists find way to make copper-catalyzed click chemistry biocompatible

Biomolecular imaging can reveal a great deal of information about the inner workings of cells and one of the most attractive targets for imaging are glycans - sugars that are ubiquitous to living organisms and abundant on cell surfaces. Imaging a glycan requires that it be tagged or labeled. One of the best techniques for doing this is a technique called click chemistry.

19 Jul 2011

Researchers capitalize on 'memories' of adult-derived stem cells for treatment of diabetes

Stem cells from early embryos can be coaxed into becoming a diverse array of specialized cells to revive and repair different areas of the body. Therapies based on these stem cells have long been contemplated for the treatment of diabetes, but have been held back by medical and ethical drawbacks.

14 Jul 2011

New strategy may combat age-associated infertility and birth defects

A strategy that has been shown to reduce age-related health problems in several animal studies may also combat a major cause of age-associated infertility and birth defects.

8 Jul 2011

Merck Serono announces recipients of second Grant for Fertility Innovation

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, today announces the recipients of its second Grant for Fertility Innovation.

8 Jul 2011

Cumulus cells can provide information about genetic and chromosomal status of eggs

At present, when a woman undergoes preimplantation genetic screening (PGS) in a fertility clinic, doctors are trying to select an egg or an embryo that is healthy and doesn't have a chromosome abnormality such as an extra copy of chromosome 21, which causes Down's syndrome. In order to establish this, they either have to biopsy a part of the egg called the polar body or remove a cell from the embryo for screening. Both procedures are expensive, invasive and can damage the egg or embryo.

6 Jul 2011

Induced pluripotent cells may make embryonic stem cells unnecessary

For nearly two decades, the medical world and the American public have grappled with the lightning-rod topic of stem cells, in particular the controversy surrounding cells from human embryos. But when researchers four years ago successfully "reprogrammed" adult body cells to become stem cells, some thought the ethical debate was nearly over. Those redirected cells, known as induced pluripotent cells, or iPS cells, show potential as therapy.

6 Jul 2011

Frozen embryo transfer may not adversely affect neonatal outcome

In the first study, French scientists looked at neonatal outcome in terms of mode of delivery, gestational age, preterm birth rate (less than 37 weeks of gestation), mean child measurements, low birth weight (less than 2,500g) and perinatal mortality. When comparing the cryo singletons to the fresh cohort, the scientists showed that mean birth weight, mean height and head circumference were lower in the fresh population.

6 Jul 2011

EIM collects data on frozen oocyte retrieval cycles for the first time

Other important data the European IVF Monitoring group (EIM) on 2008 cycles and the International Committee Monitoring Assisted Reproductive Technologies (ICMART) on 2007 cycles highlighted were Sweden's low rate of multiple births - the lowest in the world - and Spain's 30 % share of egg donations in Europe.

6 Jul 2011

Researchers investigate predictors for adverse outcome in IVF singletons

In Sweden almost 40 000 children have now been born after IVF, around 3 500 each year, and IVF children constitute 3% of all newborns. "This represents a large number of children and any adverse outcomes related to IVF are therefore a major public health issue," said Dr. Antonina Sazonova, from Sahlgrenska University Hospital, Gothenburg, Sweden, who carried out the research with colleagues from the hospital and from Lund University.

6 Jul 2011

Study: 'Vanishing twin' linked to increased risk of congenital malformations

Professor Michael Davies will tell the annual meeting of the European Society of Human Reproduction and Embryology today that the "vanishing twin" phenomenon, in which only one child is born from a pregnancy that originally starts as a multiple pregnancy, is linked to a nearly two-fold increased risk in any congenital malformation and to a nearly three-fold risk of multiple malformations.

6 Jul 2011

Cleavage stage embryo with aneuploidy can undergo genetic normalisation process

Professor William G. Kearns told the annual meeting of the European Society of Human Reproduction and Embryology that a three-day-old embryo with an incorrect number of chromosomes was capable of undergoing "a dynamic process of genetic normalisation" so that by day five, when it had developed to the blastocyst stage, it had become euploid, with the correct number of chromosomes.

5 Jul 2011