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Neoprobe commences process for listing on NYSE: AMEX stock exchange

Neoprobe Corporation, a diversified developer of innovative oncology surgical and diagnostic products, announced today it has initiated the application process for listing on the NYSE: AMEX stock exchange.

4 Aug 2010

Merck-Chimie to commercialize CardioGenics' proprietary paramagnetic beads

CardioGenics Holdings Inc., developer of the ultra-sensitive QL Care™ Point-Of-Care (POC) analyzer and products for the immunoassay segment of the In-Vitro Diagnostics market, announced that CardioGenics Inc. and Merck Chimie S.A.S. have agreed on a plan to commercialize CardioGenics' proprietary paramagnetic beads, with shipments to Merck-Chimie's customers scheduled to start mid-September 2010.

4 Aug 2010

New algorithm to reduce radiation dose in CT imaging

In recent years, advances in CT scanner technology have made perfusion computed tomography (CT) imaging an important diagnostic tool for patients with suspected stroke. Now, researchers at Mayo Clinic are working to reduce radiation dosages used to acquire perfusion and other CT images. Mayo Clinic medical physicist Cynthia McCollough, Ph.D., and her group of researchers presented their findings related to CT dose reduction at the 52nd Annual Meeting of the American Association of Physicists in Medicine on July 20 in Philadelphia. The presentation was entitled "20-Fold Dose Reduction Using a Gradient Adaptive Bilateral Filter: Demonstration Using in Vivo Animal Perfusion CT."

4 Aug 2010

Celera decreases second-quarter net loss to $6.1 million

Celera Corporation today reported net revenues of $32.6 million for the second quarter of 2010 that ended June 26, 2010, compared to $41.4 million for the prior year quarter. For the second quarter of 2010, Celera reported a net loss of $6.1 million, or $0.07 per share, compared to a net loss of $31.7 million, or $0.39 per share, for the prior year quarter.

4 Aug 2010

Premier international conference to discuss latest diagnostic tools, emerging therapies for personalized medicine

What As scientists understand more about a tumor's underlying biology, personalized medicine is emerging as the new patient management paradigm. This year, the American Association for Cancer Research will host its fourth Molecular Diagnostics in Cancer Therapeutic Development: Challenges and Horizons conference at the Sheraton Denver Downtown Hotel in Denver, Colo. This meeting regularly draws representatives from academia and industry to discuss the latest in diagnostic tools and emerging therapies.

4 Aug 2010

BCM collaborates with Roche NimbleGen for high throughput exome capture technology

The Baylor College of Medicine Human Genome Sequencing Center has standardized its target enrichment human disease research studies on Roche NimbleGen Sequence Capture Exome technology. The Baylor HGSC will sequence over 5,000 exomes in the next two years to identify genetic variants underlying multiple human diseases and will employ NimbleGen SeqCap EZ Exome and customized NimbleGen exome designs as the exome capture technology of choice. More than 15 different diseases will be investigated by Baylor HGSC, including brain, liver, pancreatic, colon, ovarian and bladder cancers, heart disease, diabetes, autism, and other inherited diseases with the goal of better understanding causative mutations and their impact on these diseases.

4 Aug 2010

Caliper Life Sciences second-quarter GAAP revenue decreases 10% to $29.0 million

Caliper Life Sciences, Inc., today reported results for its second quarter ended June 30, 2010. Second quarter GAAP revenue decreased 10% to $29.0 million from $32.1 million in the same period in 2009 as a result of divestitures in 2010 and 2009. Revenue from on-going business increased 4% on a reported basis and 6% on an organic basis (which assumes constant currency).

3 Aug 2010

OCM announces findings from Diagnostic Management Program

One Call Medical, the nation's leading provider of diagnostic testing (including MRI and CT scans) and specialty services (e.g. transportation and translation), today announced findings from its Diagnostic Management Program, revealing that on average, a typical workers' compensation payer may have as much as two-thirds of its diagnostic radiology referrals go "unmanaged," leading to overpayments, inefficiencies, and quality issues in the diagnostic referral, scheduling, and results process.

3 Aug 2010

Recommendations available for managing ascites, SBP and hepatorenal syndrome

The peer reviewed guidelines will be available in the September 2010 issue, (Volume 53, No.3) of the Journal of Hepatology and online in advance of publication at http://www.ncbi.nlm.nih.gov/pubmed/20633946 . They also provide recommendations for the management of spontaneous bacterial peritonitis and hepatorenal syndrome, which often affect patients with cirrhosis.

3 Aug 2010

Toxic protein in bee venom improves liposome encapsulated drug effectiveness

The next time you are stung by a bee, here's some consolation: a toxic protein in bee venom, when altered, significantly improves the effectiveness liposome-encapsulated drugs or dyes, such as those already used to treat or diagnose cancer. This research, described in the August 2010 print issue of the FASEB Journal, shows how modified melittin may revolutionize treatments for cancer and perhaps other conditions, such as arthritis, cardiovascular disease, and serious infections.

3 Aug 2010

New, improved ClinicTools now available

The new and improved ClinicTools is deployed. Physicians can send error-free prescriptions, including test orders, electronically. Pharmacies, labs and diagnostic centers can now register for free to increase their respective business. ClinicTools started out as simply an electronic medical record platform for healthcare providers.

3 Aug 2010

Pennsylvania to open high-risk insurance program for uninsured individuals with pre-existing medical conditions

As part of the national health insurance reform, Pennsylvania this week will open a high-risk insurance program for uninsured individuals who have pre-existing medical conditions, Insurance Commissioner Joel Ario said today.

3 Aug 2010

Researchers discover manipulation of microRNA-29a shows potential of novel IBS treatment

A possible cause of irritable bowel syndrome has been traced to a small piece of RNA that blocks a substance protecting the colon membrane, leading to hostile conditions that can produce diarrhea, bloating and chronic abdominal pain.New research shows that this RNA segment sends signals that stop the activity of the gene that produces glutamine, an amino acid. Previous research has linked a shortage of glutamine in the gut with the seepage of toxins and bacteria through the intestinal wall, irritating nerves and creating disease symptoms.

3 Aug 2010

IRIS International closes AlliedPath acquisition

IRIS International, Inc., a leading manufacturer of automated in-vitro diagnostics systems and consumables for use in hospitals and commercial laboratories worldwide, announced today that it has closed the acquisition of AlliedPath, Inc., a private, early stage high complexity, CLIA-certified laboratory focused on oncology and molecular diagnostics.

2 Aug 2010

RANZCR optimization training workshop enables radiation dose reduction in adult scans

Numerous radiology practices were able to significantly reduce the radiation dose associated with multi-detector computed tomography (MDCT) scans by participating in a one day dose optimization workshop provided by the Royal Australian and New Zealand College of Radiologists and supported by the local state health department, according to a study in the August issue of the Journal of the American College of Radiology.

2 Aug 2010

Cell-of-origin for prostate cancer identified

UCLA scientists have identified for the first time a cell-of-origin for human prostate cancer, a discovery that could result in better predictive and diagnostics tools and the development of new and more effective targeted treatments for the disease.

31 Jul 2010

COGS receives $10 million renewal grant from National Institute of Mental Health

The six-site Consortium on the Genetics of Schizophrenia (COGS), led by the director of the Schizophrenia Program at the University of California, San Diego School of Medicine, has received a $10 million renewal grant from the National Institute of Mental Health (NIMH), one of the National Institutes of Health. The grant funds an ongoing, multiple-site collaboration examining the genetic architecture of the causes and abnormalities related to schizophrenia.

31 Jul 2010

WHO expert: Faster MDR-TB test should be made available to vulnerable populations

A new diagnostic tool that shortens the diagnosis of multidrug-resistant tuberculosis (MDR-TB) from eight weeks to two hours should be made available to vulnerable populations according to a WHO expert, Reuters reports.

31 Jul 2010

Pathwork Diagnostics enters into research collaboration with Novartis

Pathwork Diagnostics Inc., a molecular diagnostics company focused on oncology, today announced that it has entered into a research collaboration with Novartis. The parties intend to discover clinically meaningful biomarker signatures that can serve as the basis for diagnostics across a range of cancer types. Under the terms of the agreement, both parties have rights to develop and commercialize the diagnostic products. Financial terms were not disclosed.

31 Jul 2010

Measuring GAPDH inhibiting antibodies can result in long-term treatment for MS

UCI immunologists have found that testing for increased levels of antibodies that inhibit energy production in neurons can detect axon and neuron degeneration in multiple sclerosis earlier than existing diagnostic tools.

31 Jul 2010

Diagnostic News and Research

Neoprobe commences process for listing on NYSE: AMEX stock exchange

Merck-Chimie to commercialize CardioGenics' proprietary paramagnetic beads

New algorithm to reduce radiation dose in CT imaging

Celera decreases second-quarter net loss to $6.1 million

Premier international conference to discuss latest diagnostic tools, emerging therapies for personalized medicine

BCM collaborates with Roche NimbleGen for high throughput exome capture technology

Caliper Life Sciences second-quarter GAAP revenue decreases 10% to $29.0 million

OCM announces findings from Diagnostic Management Program

Recommendations available for managing ascites, SBP and hepatorenal syndrome

Toxic protein in bee venom improves liposome encapsulated drug effectiveness

New, improved ClinicTools now available

Pennsylvania to open high-risk insurance program for uninsured individuals with pre-existing medical conditions

Researchers discover manipulation of microRNA-29a shows potential of novel IBS treatment

IRIS International closes AlliedPath acquisition

RANZCR optimization training workshop enables radiation dose reduction in adult scans

Cell-of-origin for prostate cancer identified

COGS receives $10 million renewal grant from National Institute of Mental Health

WHO expert: Faster MDR-TB test should be made available to vulnerable populations

Pathwork Diagnostics enters into research collaboration with Novartis

Measuring GAPDH inhibiting antibodies can result in long-term treatment for MS

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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