Genes News and Research

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Genetic code and epigenetics revealing adaption traits

A well-known songbird, the great tit, has revealed its genetic code, offering researchers new insight into how species adapt to a changing planet. Their initial findings suggest that epigenetics -- what's on rather than what's in the gene -- may play a key role in the evolution of memory and learning. And that's not just true for birds.

26 Jan 2016

Neurons protect intestinal tissue from over-inflammation

The immune system exercises constant vigilance to protect the body from external threats--including what we eat and drink. A careful balancing act plays out as digested food travels through the intestine. Immune cells must remain alert to protect against harmful pathogens like Salmonella, but their activity also needs to be tempered since an overreaction can lead to too much inflammation and permanent tissue damage.

25 Jan 2016

Carbapenem-resistant Enterobacteriaceae: an interview with Dr. Michael Dudley

Enterobacteriaceae refer to the family of bacteria such as E. coli and Klebsiella that are bacterial pathogens most frequently associated with hospital-acquired infections

25 Jan 2016

NHS Blood and Transplant now offers more detailed blood testing for patients with haemoglobinopathies

Patients with blood disorders can now get detailed blood group typing to enable better matched and potentially safer transfusions.

25 Jan 2016

UC San Diego researchers develop rapid susceptibility test for Staphylococcus aureus

A team of biologists and biomedical researchers at UC San Diego has developed a new method to determine if bacteria are susceptible to antibiotics within a few hours, an advance that could slow the appearance of drug resistance and allow doctors to more rapidly identify the appropriate treatment for patients with life threatening bacterial infections.

25 Jan 2016

Scientists find how APOBEC protein becomes dangerous when DNA replication process goes wrong

Cancer is caused by the growth of an abnormal cell which harbours DNA mutations, "copy errors" occurring during the DNA replication process. If these errors do take place quite regularly without having any damaging effect on the organism, some of them affect a specific part of the genome and cause the proliferation of the mutant cell, which then invades the organism.

25 Jan 2016

African-American pediatric lymphoma patients have inferior outcomes compared to white and Hispanic peers

Researchers from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine today published a study showing that African-American pediatric Hodgkin lymphoma patients have inferior overall survival to their white and Hispanic peers.

25 Jan 2016

CNIC researchers identify how two proteins control heart growth and adaptation to hypertension

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have identified how two proteins control the growth of the heart and its adaptation to high blood pressure (hypertension).

25 Jan 2016

Levels of mitochondrial DNA in the blood may predict chronic kidney disease risk

The health of blood cells' energy-producing mitochondria may predict a person's risk of developing chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

22 Jan 2016

PGD model could provide policy guideposts for human genome editing

Human genome editing for both research and therapy is progressing, raising ethical questions among scientists around the world.

22 Jan 2016

Colon cancer patients lacking CDX2 protein more likely to benefit from chemotherapy

Using a new computer science approach, researchers at University of California, San Diego School of Medicine, Columbia University and Stanford University discovered a distinctive molecular feature — a biomarker — that identified colon cancer patients who were most likely to remain disease-free up to five years after surgery.

22 Jan 2016

CU Cancer Center study finds distinct genetic drivers of colorectal cancer in younger and older patients

A University of Colorado Cancer Center study being presented Saturday at the 2016 Genitourinary Cancers Symposium shows genetic differences between colorectal cancer (CRC) in young and old patients, possibly pointing toward different treatments and strategies in combating the young form of the disease.

22 Jan 2016

Amgen announces approval of cholesterol-lowering medication Repatha (evolocumab) Injection in Japan

Amgen today announced that the Japanese Ministry of Health, Labour and Welfare has approved the cholesterol-lowering medication Repatha (evolocumab) Injection, the first proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor to be approved in Japan.

22 Jan 2016

Simple blood test could predict relapse in AML patients

A simple blood test capable of detecting trace levels of leukaemia cells remaining after intensive chemotherapy has been developed by scientists at the National Institute for Health Research Biomedical Research Centre at Guy’s and St Thomas’ NHS Foundation Trust and King’s College London.

22 Jan 2016

Researchers identify biomarkers that may influence potential new drug design or alternative treatments of cancer

Researchers have discovered gene-targets (biomarkers) that may enable alternative treatments or the potential design of new drugs that target metastasis-promoting tumor genes.

22 Jan 2016

Fibrosis in kidney transplants driven by continuous injury

Clinically, kidney fibrosis can be used to assess stage, progression, and prognosis for both kidney transplants and kidney disease. There is debate as to whether kidney fibrosis is a maladaptive, injury-triggered process that inherently progresses to kidney failure or an adaptive wound-healing process that stabilizes the injury site.

22 Jan 2016

New machine-learning technique could be used to uncover previously unknown features of organisms

A powerful new machine-learning technique can be applied to large datasets in the biological sciences to uncover previously unknown features of organisms and their genes, according to a team led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

22 Jan 2016

Duke researchers closer to developing rapid blood test for bacterial and viral infections

Researchers at Duke Health are fine-tuning a test that can determine whether a respiratory illness is caused by infection from a virus or bacteria so that antibiotics can be more precisely prescribed.

21 Jan 2016

Study explores role of genetic and environmental factors in development of social anxiety

Genes play a crucial role over time although environmental factors matter most in the short term, according to a major study into social anxiety and avoidant personality disorders from the Norwegian Institute of Public Health.

21 Jan 2016

Northwestern researchers use fruit fly genetics to understand how things may go wrong in cancer

Cancer cells are normal cells that go awry by making bad developmental decisions during their lives. In a study involving the fruit fly equivalent of an oncogene implicated in many human leukemias, Northwestern University researchers have gained insight into how developing cells normally switch to a restricted, or specialized, state and how that process might go wrong in cancer.

21 Jan 2016

Genes News and Research

Genetic code and epigenetics revealing adaption traits

Neurons protect intestinal tissue from over-inflammation

Carbapenem-resistant Enterobacteriaceae: an interview with Dr. Michael Dudley

NHS Blood and Transplant now offers more detailed blood testing for patients with haemoglobinopathies

UC San Diego researchers develop rapid susceptibility test for Staphylococcus aureus

Scientists find how APOBEC protein becomes dangerous when DNA replication process goes wrong

African-American pediatric lymphoma patients have inferior outcomes compared to white and Hispanic peers

CNIC researchers identify how two proteins control heart growth and adaptation to hypertension

Levels of mitochondrial DNA in the blood may predict chronic kidney disease risk

PGD model could provide policy guideposts for human genome editing

Colon cancer patients lacking CDX2 protein more likely to benefit from chemotherapy

CU Cancer Center study finds distinct genetic drivers of colorectal cancer in younger and older patients

Amgen announces approval of cholesterol-lowering medication Repatha (evolocumab) Injection in Japan

Simple blood test could predict relapse in AML patients

Researchers identify biomarkers that may influence potential new drug design or alternative treatments of cancer

Fibrosis in kidney transplants driven by continuous injury

New machine-learning technique could be used to uncover previously unknown features of organisms

Duke researchers closer to developing rapid blood test for bacterial and viral infections

Study explores role of genetic and environmental factors in development of social anxiety

Northwestern researchers use fruit fly genetics to understand how things may go wrong in cancer

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