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Researchers identify four new target molecules for future personalized MS treatment

Currently available therapies to treat multiple sclerosis (MS) lack precision and can lead to serious side effects.

27 Apr 2022

Penn scientists discover how one inflammatory disorder increases susceptibility to another

The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, perpetuating a misguided immune response.

27 Apr 2022

“Keto” molecule could someday become a part of colorectal cancer care and prevention

A molecule produced in the liver in response to low-carb "ketogenic" diets has a powerful effect in suppressing colorectal tumor growth and may be useful as a preventive and treatment of such cancers, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

27 Apr 2022

Genetic cause of lupus identified

An international team of researchers has identified DNA mutations in a gene that senses viral RNA, as a cause of the autoimmune disease lupus, with the finding paving the way for the development of new treatments.

27 Apr 2022

Comparative analysis of transcriptional responses across 13 different vaccines

A new study aimed to carry out a comparative analysis of transcriptional responses from 820 healthy young adults across 13 different vaccines.

27 Apr 2022

How severity and progression of COVID-19 affect cytokine profiles in pregnant women

The current study deals with the results of serum cytokine analysis in a small group of pregnant women with and without COVID-19 in the third trimester in a single New York City hospital.

27 Apr 2022

CRISPR/Cas9 deletions induce adverse on-target genomic effects

Researchers utilized a CRISPR/Cas9 system to evaluate the usage of tRNA by deleting two tRNA genes from the genomes of hyper hepatocellular carcinoma and human near-haploid chronic myeloid leukemia cells.

27 Apr 2022

Bebtelovimab potently neutralizes all SARS-CoV-2 variants of concern

The current study, escribes a new mAb LY-CoV1404 (bebtelovimab) from Eli Lilly, with high neutralization potency with a broad spectrum of activity across all current variants.

27 Apr 2022

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

In a study published in Cells, researchers have been investigating the effects of this extract for use against COVID-19.

27 Apr 2022

Cellular reprogramming can lead to better liver tissue regeneration in mice

Mammals can't typically regenerate organs as efficiently as other vertebrates, such as fish and lizards. Now, Salk scientists have found a way to partially reset liver cells to more youthful states - allowing them to heal damaged tissue at a faster rate than previously observed.

27 Apr 2022

Corticosteroid exposure associated with hospitalization for severe pain event among patients with sickle cell disease

People with sickle cell disease (SCD) who were recently prescribed a corticosteroid – a medicine frequently used to treat asthma or inflammation – were found to be significantly more likely to be hospitalized for a severe pain event, according to a paper published today in the journal Blood.

27 Apr 2022

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Scientists from Germany have recently identified Hypericum perforatum, a widespread herbal plant known as St. John's wort, as a potential antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is published in the journal Pharmaceuticals.

27 Apr 2022

Research highlights importance of booster vaccine doses to protect against all Omicron variants

In a recent study published in the Cell Host and Microbe journal, researchers examined the neutralization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1, BA.1.1, and BA.2 sublineages.

27 Apr 2022

Superior T-cell immunity in COVID vaccinated

A recent study published in the journal Public Library of Science (PLOS) ONE presented the T cell and humoral immune responses following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and infection against the SARS-CoV-2 original and mutant strains.

27 Apr 2022

Discovery about human cells’ stress response could deepen the understanding of various cancers

The communications line between two critical parts of a human cell could be the key to cell survival under stress - a discovery that could deepen our understanding of various cancers, according to new research from the University of Surrey.

26 Apr 2022

Well-established group of antimalarials unlikely to be affected by resistance, study shows

New research published today in Antimicrobial Agents and Chemotherapy, shows that the well-established group of antimalarials, known as artemisinins, are unlikely to be affected by resistance.

26 Apr 2022

Roswell Park experts to share latest advances in the treatment of blood-related cancers

Roswell Park Comprehensive Cancer Center specialists will share the latest advances and developments in the treatment of blood-related cancers at the 2022 Tandem Transplantation & Cellular Therapy Meetings of the American Society for Transplantation and Cellular Therapy (ASTCT) and Center for International Blood and Marrow Transplant Research (CIBMTR) in Salt Lake City, Utah, from April 23 to 26.

26 Apr 2022

Antibodies against the original strain of SARS-CoV-2 may not work as well with omicron

If you're wondering why after two vaccination doses and a booster shot, you still got sick from the omicron strain of the virus that causes COVID-19, one possible answer may have been found in a recent study by researchers at Johns Hopkins Medicine and the National Institute of Allergy and Infectious Diseases at the National Institutes of Health.

26 Apr 2022

New insights into the link between EMFs, calcium and Alzheimer’s disease

For almost a quarter of a century, researchers have been studying and publishing on the effect of calcium on Alzheimer's Disease. Research has led to the development of the calcium hypothesis of Alzheimer's disease, which argues that Alzheimer's is caused by excessive intracellular calcium.

26 Apr 2022

New discovery about nature’s ‘high-end machinery’ could have big implications for biology

Working with tiny bacteria, Michigan State University researchers led by Lee Kroos have made a discovery that could have big implications for biology.

26 Apr 2022

Cell News and Research

Researchers identify four new target molecules for future personalized MS treatment

Penn scientists discover how one inflammatory disorder increases susceptibility to another

“Keto” molecule could someday become a part of colorectal cancer care and prevention

Genetic cause of lupus identified

Comparative analysis of transcriptional responses across 13 different vaccines

How severity and progression of COVID-19 affect cytokine profiles in pregnant women

CRISPR/Cas9 deletions induce adverse on-target genomic effects

Bebtelovimab potently neutralizes all SARS-CoV-2 variants of concern

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

Cellular reprogramming can lead to better liver tissue regeneration in mice

Corticosteroid exposure associated with hospitalization for severe pain event among patients with sickle cell disease

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Research highlights importance of booster vaccine doses to protect against all Omicron variants

Superior T-cell immunity in COVID vaccinated

Discovery about human cells’ stress response could deepen the understanding of various cancers

Well-established group of antimalarials unlikely to be affected by resistance, study shows

Roswell Park experts to share latest advances in the treatment of blood-related cancers

Antibodies against the original strain of SARS-CoV-2 may not work as well with omicron

New insights into the link between EMFs, calcium and Alzheimer’s disease

New discovery about nature’s ‘high-end machinery’ could have big implications for biology

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