Immune System News and Research

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Researchers find safety mechanism in immune system in people with autoimmune diseases

Monash University researchers have found an important safety mechanism in the immune system that may malfunction in people with autoimmune diseases, such as Multiple Sclerosis, potentially paving the way for innovative treatments.

6 Sep 2013

UCSF to receive grant to study gene sequencing aimed at detecting disorders in newborns

UC San Francisco will receive $4.5 million over the next five years for a pilot project to assess whether large-scale gene sequencing aimed at detecting disorders and conditions can and should become a routine part of newborn testing.

6 Sep 2013

Scientists reveal structure of protein essential for triggering necroptosis

Scientists in Melbourne, Australia, have revealed the structure of a protein that is essential for triggering a form of programmed cell death called necroptosis, making possible the development of new drugs to treat chronic inflammatory diseases such as Crohn's disease and rheumatoid arthritis.

6 Sep 2013

Apoptosis can reactivate latent herpesviruses in dying cell

Researchers have found that apoptosis, a natural process of programmed cell death, can reactivate latent herpesviruses in the dying cell. The results of their research, which could have broad clinical significance since many cancer chemotherapies cause apoptosis, was published ahead of print in the Journal of Virology.

6 Sep 2013

Behavior problems in childhood may lead to inflammatory conditions later in life

Children with behavioral problems may be at risk of many chronic diseases in adulthood including heart disease, obesity, diabetes, as well as inflammatory illnesses (conditions which are caused by cell damage).

6 Sep 2013

Acute manic episodes linked to increased edema risk

Bipolar disorder patients admitted to hospital with a manic episode are at an increased risk for lower limb edema, compared with their peers with depressive or non-affective psychosis episodes, study findings show.

5 Sep 2013

Rigel Cuts 30 Jobs, Refocuses On Three Clinical Programs

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5 Sep 2013

Dopamine improves deficiencies in social behavior, could have implications for neuropsychiatric disorders

A stressful pregnancy might be the last thing a future mother needs, but it is to her unborn baby that this stress spells real trouble. All because stress hormones (called glucocorticoids or GCs) can disturb normal foetal brain development, leading to behavioural and/or emotional problems later in life.

5 Sep 2013

Rigel plans to focus on completing three clinical programs for ITP, DLE and dry eye disease

Rigel Pharmaceuticals, Inc. today announced its plans to focus the Company's resources on the completion of three lead clinical programs. These efforts include commencing a Phase 3 clinical study of fostamatinib, an oral SYK inhibitor, in Immune Thrombocytopenic Purpura pending discussions with regulatory agencies.

5 Sep 2013

Technology used to treat cancer also functions as micro rocket for spacecraft

Nanosatellites are smartphone-sized spacecraft that can perform simple, yet valuable, space missions. Dozens of these little vehicles are now tirelessly orbiting the earth performing valuable functions for NASA, the Department of Defense and even private companies.

5 Sep 2013

Study finds similar antibody levels among 4 PCV13 immunization schedules

The use of 4 different 13-valent pneumococcal conjugate vaccine immunization schedules in healthy term infants resulted in no statistically significant differences in antibody levels between the infants after the booster dose at 12 months of age for almost all serotypes, according to a study in the September 4 issue of JAMA.

5 Sep 2013

New influenza vaccine delivered via microneedle avoids pain and side effects

Scientists have developed an influenza vaccine delivered via microneedle patch that provided 100 percent protection against a lethal influenza virus in mice more than one year after vaccination. They report their findings in the September 2013 issue of the journal Clinical and Vaccine Immunology.

5 Sep 2013

Natural compound in broccoli helps reduce risk for skin cancer

With skin cancer emerging as one of the world's most prevalent forms of cancer, researchers are using every tool at their disposal to fight this disease. The tool of choice for Sally Dickinson, PhD? Broccoli.

5 Sep 2013

High-income and better hygiene countries exhibit much higher rates of Alzheimer's

New research has found a "very significant" relationship between a nation's wealth and hygiene and the Alzheimer's "burden" on its population. High-income, highly industrialised countries with large urban areas and better hygiene exhibit much higher rates of Alzheimer's.

5 Sep 2013

Parkin protein plays key role in destruction of bacteria that cause tuberculosis

A protein at the center of Parkinson's disease research now also has been found to play a key role in causing the destruction of bacteria that cause tuberculosis, according to scientists led by UC San Francisco microbiologist and tuberculosis expert Jeffery Cox, PhD.

5 Sep 2013

Research findings raise hope for new heart therapies

Many people who survive a heart attack find themselves back in the hospital with a failing heart just years later. And the outcome often is unfavorable, owing to limited treatment options. But scientists at Temple University School of Medicine's Cardiovascular Research Center recently found hope in an unlikely source - stem cells in cortical, or compact, bone.

5 Sep 2013

Blocking a protein helps virus to thrive and restore immune function to fight HCV infection

The hepatitis C virus hijacks the body's immune system, leaving T cells unable to function. A new study in animal models suggests that blocking a protein that helps the virus thrive could restore immune function, allowing the body to fight infection. The work, led by teams at The Research Institute at Nationwide Children's Hospital and Emory University, was published online Aug. 26 in the Proceedings of the National Academy of Sciences.

4 Sep 2013

Study looks for molecular changes in genome caused by multiple sclerosis

The National Institutes of Health (NIH) awarded Benaroya Research Institute at Virginia Mason (BRI) a $1.9 million grant to find marks in the human genome which can explain why some white blood cells cause damage to the spinal cord and brain in multiple sclerosis (MS).

4 Sep 2013

Precisely designed macromolecule mimics binding of HIV to immune system cells

A precisely designed macromolecule that mimics the binding of HIV to immune system cells could be used to stop the virus from physically entering the body, according to a new study led by a materials scientist at Queen Mary University of London.

4 Sep 2013

Study shows how stomach bacteria manipulates human immune system to survive in stomach

Helicobacter pylori is a bacterium that establishes a life-long stomach infection in humans, which in some cases can lead to duodenal ulcers or stomach cancer. New research, presented at this week's Society for General Microbiology Autumn Conference, gives us a clearer understanding of how these bacteria can manipulate the human immune system to survive in the mucosal lining of the stomach.

4 Sep 2013

Immune System News and Research

Researchers find safety mechanism in immune system in people with autoimmune diseases

UCSF to receive grant to study gene sequencing aimed at detecting disorders in newborns

Scientists reveal structure of protein essential for triggering necroptosis

Apoptosis can reactivate latent herpesviruses in dying cell

Behavior problems in childhood may lead to inflammatory conditions later in life

Acute manic episodes linked to increased edema risk

Rigel Cuts 30 Jobs, Refocuses On Three Clinical Programs

Dopamine improves deficiencies in social behavior, could have implications for neuropsychiatric disorders

Rigel plans to focus on completing three clinical programs for ITP, DLE and dry eye disease

Technology used to treat cancer also functions as micro rocket for spacecraft

Study finds similar antibody levels among 4 PCV13 immunization schedules

New influenza vaccine delivered via microneedle avoids pain and side effects

Natural compound in broccoli helps reduce risk for skin cancer

High-income and better hygiene countries exhibit much higher rates of Alzheimer's

Parkin protein plays key role in destruction of bacteria that cause tuberculosis

Research findings raise hope for new heart therapies

Blocking a protein helps virus to thrive and restore immune function to fight HCV infection

Study looks for molecular changes in genome caused by multiple sclerosis

Precisely designed macromolecule mimics binding of HIV to immune system cells

Study shows how stomach bacteria manipulates human immune system to survive in stomach

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