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Research progress on the three-dimensional interaction between virus and host genome

A recent study reviewed the current progress on 3D interactions between host and viral genomes.

8 Aug 2022

Terminally exhausted T cells may remain competent for transcription, researchers say

During a battle with cancer, T cells can become exhausted and are no longer able to function properly. The early phase of exhaustion can sometimes be reversed with immunotherapy drugs, but once T cells become too exhausted, it had been thought that this state was irreversible. However, new insights from University of Pittsburgh and UPMC researchers suggest that even the most fatigued T cells can be revived.

8 Aug 2022

Study finds COVID associated with abnormal placental pathologies in nearly 50% of cohort

Researchers describe the impact of placental morphological changes in COVID-19 on pregnancy outcomes.

7 Aug 2022

Saliva-based self-testing platform detects SARS-CoV-2 with the same level of sensitivity as PCR tests

PCR tests, also called molecular tests or nucleic acid tests, are considered the gold standard in detecting the presence of SARS-CoV-2, the virus that gives rise to COVID-19.

5 Aug 2022

Heart failure arises from mutations in distinct genes, study finds

Heart failure is a common and devastating disorder for which there is no cure. Many cardiomyopathies - conditions that make it difficult for the heart to pump blood such as dilated cardiomyopathy (DCM) and arrhythmogenic cardiomyopathy (ACM) - can lead to heart failure, but treatments for patients with heart failure do not take these distinct conditions into account.

5 Aug 2022

Study provides new insight into the cellular and molecular biology of human heart failure

Studying heart samples from patients with cardiomyopathies, as well as from controls without heart disease, researchers have provided new insights into the cellular and molecular biology of human heart failure – a highly fatal condition that affects 23 million people worldwide.

5 Aug 2022

Individual genetic defects lead to heart failure in different ways, consortium reports

Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium reports in Science.

4 Aug 2022

Polymer-embedded copper-based nanoparticles prevent surface contamination by viruses

In a new study, researchers developed nanocomposite coatings to prevent surface contamination by a human coronavirus (HCoV).

4 Aug 2022

Scientists develop nanoparticle-based biosensing device for rapid and ultrasensitive detection of SARS-CoV-2

Researchers developed a gold nanoparticle-based biosensing device for rapid and ultrasensitive detection of SARS-CoV-2 in point-of-care settings.

4 Aug 2022

A combined influenza and COVID-19 mRNA vaccine

A combined mRNA vaccine is capable of inducing broad and durable protection against co-infection with SARS-CoV-2 and IAV,

3 Aug 2022

The aging human brain

Researchers describe alterations at the molecular and cellular levels that underly brain aging in otherwise healthy elderly adults.

3 Aug 2022

Are cattle at risk of SARS-CoV-2 infection?

Researchers evaluated antibodies targeting SARS-CoV-2 in cattle from farms in Germany.

3 Aug 2022

Pre-existing anti-SARS-CoV-2 immunity decreases viral spread but increase SARS-CoV-2 Omicron competitiveness in hamsters

In a new study, researchers assessed the impact of pre-existing immunity against SARS-CoV-2 acquired by previous infections (PI) or COVID-19 vaccination on the transmission of SARS-CoV-2 variants of concern such as Delta and Omicron.

2 Aug 2022

Study aims to assess the accuracy of influenza rapid diagnostic tests

JMIR Publications recently published "Diagnostic Accuracy of an At-Home, Rapid Self-test for Influenza: Prospective Comparative Accuracy Study" in JMIR Public Health and Surveillance which reported that rapid diagnostic tests (RDTs) for influenza used by individuals at home could potentially expand access to testing and reduce the impact of influenza on health systems.

2 Aug 2022

Würzburg scientists are working on the development of new drugs to combat monkeypox

Poxviruses pose a threat to humanity that should be taken seriously, as the current outbreak of monkeypox shows.

1 Aug 2022

How and when do de novo SARS-CoV-2 spike mutations emerge?

Researchers evaluated viral mutations in two patients with persistent SARS-CoV-2 infection.

1 Aug 2022

Study investigates the combined effects of aging and HIV-1 Tat expression in mice

A new research paper was published in Aging ("Aging (Albany NY)" by Medline/PubMed, "Aging-US" by Web of Science) Volume 14, Issue 13, entitled, "Age-related neuroendocrine, cognitive, and behavioral co-morbidities are promoted by HIV-1 Tat expression in male mice."

29 Jul 2022

Transcription News and Research

Research progress on the three-dimensional interaction between virus and host genome

Terminally exhausted T cells may remain competent for transcription, researchers say

Study finds COVID associated with abnormal placental pathologies in nearly 50% of cohort

Saliva-based self-testing platform detects SARS-CoV-2 with the same level of sensitivity as PCR tests

Heart failure arises from mutations in distinct genes, study finds

Study provides new insight into the cellular and molecular biology of human heart failure

Individual genetic defects lead to heart failure in different ways, consortium reports

Polymer-embedded copper-based nanoparticles prevent surface contamination by viruses

Scientists develop nanoparticle-based biosensing device for rapid and ultrasensitive detection of SARS-CoV-2

A combined influenza and COVID-19 mRNA vaccine

The aging human brain

Are cattle at risk of SARS-CoV-2 infection?

Pre-existing anti-SARS-CoV-2 immunity decreases viral spread but increase SARS-CoV-2 Omicron competitiveness in hamsters

Study aims to assess the accuracy of influenza rapid diagnostic tests

Würzburg scientists are working on the development of new drugs to combat monkeypox

How and when do de novo SARS-CoV-2 spike mutations emerge?

Study investigates the combined effects of aging and HIV-1 Tat expression in mice

The bat-virus relationship examined

Study finds molnupiravir well-tolerated, and effective in vaccinated and unvaccinated

Icelandic study reveals how many children experience severe COVID symptoms

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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