Genes News and Research

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UCL Cancer Institute win $200,000 CytoFLEX Flow Cytometer from Beckman Coulter

An internationally renowned gene therapy research team has won a $200,000 CytoFLEX Flow Cytometer from Beckman Coulter Life Sciences.

From Beckman Coulter Life Sciences - Flow Cytometry 18 Dec 2015

Findings show promising evidence for creating broad-spectrum antiviral

UW researchers working in collaboration with Kineta Inc. and the University of Texas at Galveston have shown that making a drug-like molecule to turn on innate immunity can induce genes to control infection in several -known viruses.

18 Dec 2015

Research opens door to validation studies in multiple tumor types of liquid biopsy

Pancreatic cancer tumors spill their molecular secrets into the blood stream, shedding their complete DNA and RNA wrapped inside protective lipid particles that make them ripe for analysis with a liquid biopsy, researchers at The University of Texas MD Anderson Cancer Center report online at the Annals of Oncology.

18 Dec 2015

Scientists identify overlooked consequence of spatial separation of cells into nucleus, cytoplasm

Genetically identical cells do not always behave the same way. According to the accepted theory, the reason are random molecular processes - known as random noise. For decades this view has been underpinned by numerous experiments and theoretical models.

18 Dec 2015

Family members of CUP patients at higher risk of developing CUP themselves

Cancer usually begins in one location and then spreads, but in 3 percent to 5 percent of cancer patients, the tissue where a cancer begins is unknown. In these individuals a cancer diagnosis is made because it has metastasized to other sites. Patients with these so-called "cancers of unknown primary," or CUP, have a very poor prognosis, with a median survival of three months.

18 Dec 2015

New study sheds light on the molecular basis of memory and learning

The brain still harbours many unknowns. Basically, it is assumed that it stores experiences by altering the connections between brain cells. This ability to adapt - which is also called "plasticity" - provides the basis for memory and learning, which is the ability to draw conclusions from memories. On a molecular scale these changes are mediated by modifications of expression of specific genes that as required strengthen or weaken the connections between the brain cells.

18 Dec 2015

UA developing brain-scanning technology that could improve diagnosis of many disorders

Researchers at the University of Arizona are developing a noninvasive brain-scanning technology that could produce images far superior to those obtained with the most commonly used systems -- electroencephalography and functional magnetic resonance imaging.

17 Dec 2015

UMMS researchers identify new life cycle stage in HIV infection

Researchers at the University of Massachusetts Medical School have identified a new life cycle stage in HIV infection, thanks to a novel technique they developed to take images of intact infected cells.

17 Dec 2015

Five research centres get £10 million to explore how maths, statistics can help tackle serious health challenges

Life Sciences Minister George Freeman today (16 December) announced £10 million investment in five new research centres around the UK that will explore how mathematics and statistics can help clinicians to tackle serious health challenges such as cancer, heart disease and antibiotic resistant bacteria.

17 Dec 2015

Researchers find new way to prevent or reduce pathologies caused by malformed proteins

Improperly formed proteins can cause a host of serious illnesses, from muscular dystrophy to cystic fibrosis. A question of enormous import in research, beyond the challenge of determining how malformed proteins contribute to specific disease processes, is figuring out ways to prevent or reduce the pathologies they cause.

16 Dec 2015

Many gene variants affect person's response to medication

In recent decades much hope was based on the development of personalised drug treatments, in which genetic tests determine the choice and optimal dose of medication for each individual patient. However, the real breakthrough is still to be seen, and now researchers at Karolinska Institutet show in two separate scientific papers that many more gene variants affect how a person responds to medication than previously thought - and thus that today's analytical tools are too coarse.

16 Dec 2015

Bile acid may help treat fatty liver disease and obesity

A bile acid that can turn off a receptor in the gut has prevented and reversed fatty liver disease in mice, according to an international team of researchers. The compound may help treat certain metabolic disorders, such as Type 2 diabetes and obesity, as well.

16 Dec 2015

Cancer drug may protect kidneys from damage caused by chemotherapy agent cisplatin

A class of drugs used increasingly to help fight cancer may have the additional benefit of protecting the kidneys when packaged with the powerful chemotherapy agent cisplatin.

16 Dec 2015

Discovery could pave way for targeted therapies to treat penile cancer

Researchers have identified potential genetic alterations in penile cancer that could pave the way for targeted treatments.

15 Dec 2015

Researchers discover novel way to enhance, restore cancer suppressor activity in B-ALL

Researchers at Penn State College of Medicine, working with Chinese and American colleagues, have discovered a novel way to enhance and restore cancer suppressor activity in B-cell acute lymphoblastic leukemia, resulting in better outcomes in a pre-clinical model of the disease. The finding could pave the way for a new class of drugs for this and other forms of leukemia.

15 Dec 2015

New study describes a way to identify complex type of mutation in cancer genomes

New research shows that current approaches to genome analysis systematically miss detecting a certain type of complex mutation in cancer patients' tumors. Further, a significant percentage of these complex mutations are found in well-known cancer genes that could be targeted by existing drugs, potentially expanding the number of cancer patients who may benefit.

15 Dec 2015

Study may help reduce sugar consumption, improve nutritional health of children

Everyone knows that children love sweets, but ever wonder why some kids seem to want more sugary food than others? It could be because they need more sugar to get that same sweet taste. According to new research from the Monell Center, sensitivity to sweet taste varies widely across school-aged children and is in part genetically-determined.

15 Dec 2015

Genes vital for age-related cognitive declines in memory identified in adult worm neurons

Researchers from Princeton University have identified genes important for age-related cognitive declines in memory in adult worm neurons, which had not been studied previously. The research, published in the journal Nature, could eventually point the way toward therapies to extend life and enhance health in aging human populations.

15 Dec 2015

Stanford researchers develop novel technique for mapping diversity of gut bacteria

A collaboration between computer scientists and geneticists at Stanford University has produced a novel technique for mapping the diversity of bacteria living in the human gut.

15 Dec 2015

Human body clock study paves way for drug treatment of osteoarthritis

A University of Manchester biologist has for the first time established that the painful and debilitating symptoms endured by osteoarthritis sufferers are intrinsically linked to the human body clock.

15 Dec 2015

Genes News and Research

UCL Cancer Institute win $200,000 CytoFLEX Flow Cytometer from Beckman Coulter

Findings show promising evidence for creating broad-spectrum antiviral

Research opens door to validation studies in multiple tumor types of liquid biopsy

Scientists identify overlooked consequence of spatial separation of cells into nucleus, cytoplasm

Family members of CUP patients at higher risk of developing CUP themselves

New study sheds light on the molecular basis of memory and learning

UA developing brain-scanning technology that could improve diagnosis of many disorders

UMMS researchers identify new life cycle stage in HIV infection

Five research centres get £10 million to explore how maths, statistics can help tackle serious health challenges

Researchers find new way to prevent or reduce pathologies caused by malformed proteins

Many gene variants affect person's response to medication

Bile acid may help treat fatty liver disease and obesity

Cancer drug may protect kidneys from damage caused by chemotherapy agent cisplatin

Discovery could pave way for targeted therapies to treat penile cancer

Researchers discover novel way to enhance, restore cancer suppressor activity in B-ALL

New study describes a way to identify complex type of mutation in cancer genomes

Study may help reduce sugar consumption, improve nutritional health of children

Genes vital for age-related cognitive declines in memory identified in adult worm neurons

Stanford researchers develop novel technique for mapping diversity of gut bacteria

Human body clock study paves way for drug treatment of osteoarthritis

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