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New type of sulfite reductase

Biswarup Mukhopadhyay and Eric Johnson from the Virginia Bioinformatics Institute at Virginia Tech have discovered a novel enzyme that represents an ancient detoxification system and provides a clue to the development of early metabolism on earth.

7 Dec 2005

Garvan scientists explain stress and sickness

Garvan Institute scientists have discovered how a hormone, known as neuropeptide Y (NPY), can prevent our immune system functioning properly, paving the way for two new major opportunities for therapeutic intervention.

7 Dec 2005

Significant relationships between household endotoxin and diagnosed asthma

Exposure to household endotoxin levels poses a significant risk for asthma, according to the first nationwide sampling of house dust.

2 Dec 2005

Protein target for Parkinson's disease

Researchers at Johns Hopkins' Institute for Cell Engineering (ICE) have discovered a protein that could be the best new target in the fight against Parkinson's disease since the brain-damaging condition was first tied to loss of the brain chemical dopamine.

2 Dec 2005

New anthrax antibody

A new anthrax antibody engineered by scientists at The University of Texas at Austin protects and defends against inhalation anthrax without the use of antibiotics and other more expensive antibodies.

2 Dec 2005

Bacterial DNA and IVF contamination risk on New Scientist

Some children conceived by a common method of IVF could be carrying chunks of bacterial DNA in their chromosomes, according to a study in mice. The researchers who conducted the work say that such accidental genetic modification would be very rare, but they argue that fertility doctors should take more precautions to exclude it.

30 Nov 2005

Cranberry flavoured toothpaste may help stop decay

According to researchers cranberries, well-known for their ability to help thwart urinary tract infections, may also help prevent tooth decay and cavities.

28 Nov 2005

Cranberry juice protects teeth against cavities

Families gathered around the Thanksgiving dinner table might consider giving thanks for the bacteria-busting ability of cranberry juice, say dental researchers who have discovered that the beverage holds important clues for preventing cavities.

26 Nov 2005

Compound from Salinispora (marine bacteria) kills blood cancer cells

An anti-cancer compound derived from bacteria dwelling in ocean-bottom sediments appears in laboratory tests to be a potent killer of drug-resistant multiple myeloma cells, and potentially with less toxicity than current treatments, report Dana-Farber Cancer Institute researchers in the November issue of Cancer Cell.

21 Nov 2005

Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence

By using pathogenic fungi as model systems for understanding fungal diseases, two groups of researchers are reporting new work that offers insight into how carbon dioxide (CO2) governs the morphogenic changes that allow pathogenic fungi to survive in different environments and invade the human body

21 Nov 2005

Study of how bacteria change their metabolic networks

Bacteria feel pressures to evolve antibiotic resistance and other new abilities in response to a changing environment, and they react by 'stealing' genetic information from other better-adapted types of bacteria, according to research published in Nature Genetics.

20 Nov 2005

Study reveals how T cells analyze and react to the signals of infection at the immunological synapse

The immune system is highly complex. The cast of characters alone required to marshal an immune response to a foreign invader can number in the millions as the body's soldiers, T cells, are called into action.

20 Nov 2005

Six gene variants predict heart muscle damage after cardiac surgery

Duke University Medical Center researchers have found that patients with six specific variants of genes involved in the body's immune response are significantly more likely to suffer damage of heart tissue after cardiac surgery.

16 Nov 2005

Clinical decision support system reduces overall use of antimicrobials for colds, bronchitis and sinusitis

A clinical decision support system intervention reduced the overall use of antimicrobials for respiratory tract infections such as colds, bronchitis and sinusitis, according to a study in the JAMA: The Journal of the American Medical Association.

15 Nov 2005

Australian study highlights lateral genetic transfer

A University of Queensland study mapping the evolution of genes has shed light on the role of gene transfer in bacterial diseases.

14 Nov 2005

Protein discovery may have implications for treating E. coli 0157:H7 infection

A discovery by Queen's researchers of a previously unknown protein may open the door to more effective treatment of a deadly strain of the E. coli bacteria.

14 Nov 2005

Scientists discover why lung, but not skin, anthrax infections are lethal

Scientists from the Max Planck Institute for Infection Biology in Berlin discovered why lung, but not skin, anthrax infections are lethal. As reported in the newest issue of PloS Pathogen (November 2005) Neutrophils, a form of white blood cells, play a key role in anthrax infections.

13 Nov 2005

Antibiotics overprescribed for sore throat

Physicians prescribe antibiotics for more than half of children with sore throat, exceeding the expected prevalence of strep throat, and used nonrecommended antibiotics for 27 percent of children who received an antibiotic prescription, according to a study in the November 9 issue of JAMA: The Journal of the American Medical Association.

13 Nov 2005

Specific bacterial markers for bacterial vaginosis discovered

Findings reported in this week's New England Journal of Medicine (November 3 issue) highlight promising findings from two Seattle-based researchers on the origins of bacterial vaginosis (BV).

7 Nov 2005

New high-resolution data on intact ribosome

A new, sharper picture of the nano-machine that translates our genetic program into proteins promises to help researchers explain how some types of antibiotics work and could lead to the design of better ones.

7 Nov 2005