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Potential new treatment approaches for liver diseases

By discovering the new mechanism by which estrogen suppresses lipid synthesis in the liver, UC Irvine endocrinologists have revealed a potential new approach toward treating certain liver diseases.

24 May 2013

New approach to genetic engineering reduces time and effort needed to insert genes into bacteria

A new, streamlined approach to genetic engineering drastically reduces the time and effort needed to insert new genes into bacteria, the workhorses of biotechnology, scientists are reporting.

24 May 2013

Promising approach to prevent emergence of drug-resistant forms of cancer

Re-routing anti-cancer drugs to the "power plants" that make energy to keep cells alive is a promising but long-neglected approach to preventing emergence of the drug-resistant forms of cancer - source of a serious medical problem, scientists are reporting.

24 May 2013

Researchers explore targeted therapies for prostate cancer

Are certain drugs more effective against some types of prostate cancers than others? Researchers know that not all therapies work for all patients – the next question is to figure out how to match the right treatments with the right patients.

24 May 2013

Wisconsin scientists synthesize potent compounds to curb bacteria that cause staph infections

In an age when microbial pathogens are growing increasingly resistant to the conventional antibiotics used to tamp down infection, a team of Wisconsin scientists has synthesized a potent new class of compounds capable of curbing the bacteria that cause staph infections.

24 May 2013

Cenix BioScience, Debiopharm partner to develop novel therapeutic drug candidates

Cenix BioScience, a leading preclinical contract research provider and technology developer specialized in RNAi-, miRNA- and high content-driven pharmacology, and Debiopharm Group, a Swiss-based global biopharmaceutical group of companies with a focus on the development of prescription drugs that target unmet medical needs, including oncology and companion diagnostics, today announced that they have signed a research agreement to support Debiopharm in its ongoing efforts to develop novel therapeutic drug candidates.

23 May 2013

The Immortality Project awards $2.3M to study near-death experiences, beliefs in afterlife

Phenomena related to near-death experiences, immortality in virtual reality, and genes that prevent a species of freshwater hydra from aging are among the first research proposals funded by The Immortality Project at the University of California, Riverside.

23 May 2013

Viewpoints: Mass. experience may not be true test for national health law; 'Dishonest' campaign by medical device makers

Massachusetts is often held up as a window into America's health insurance future, because it embarked on what came to be called the Romneycare reform six years ago. Like the Affordable Care Act provisions going into effect nationwide next year, Romneycare aimed to increase the fraction of the population with health insurance by imposing mandates on employers and employees and by subsidizing health insurance plans for middle-class families without employer plans.

23 May 2013

NIH-funded study raises hope for recovery of some adult patients with brain disorder

Scientists have reversed behavioral and brain abnormalities in adult mice that resemble some features of schizophrenia by restoring normal expression to a suspect gene that is over-expressed in humans with the illness.

23 May 2013

Viewpoints: Slowing health costs; What causes genetic testing to be so expensive; Iowa governor offers Medicaid supports a 'glimmer of hope'

We have done it. We have decreased the increase in the cost of healthcare. ... Is this decline the desperately needed bend in the healthcare cost curve or just the impact of the depressed economy? ... A slower growth of healthcare cost would mean less burden on the individual family, freeing that family to invest in and live a higher quality of life.

22 May 2013

Rice University computational study tracks regulatory mechanisms of E. coli cells

Environment is not the only factor in shaping regulatory patterns -- and it might not even be the primary factor, according to a new Rice University study that looks at how cells' protein networks relate to a bacteria's genome.

22 May 2013

Caltech biologists show that microRNA-146a protects stem cells during inflammation

When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But repeated infections and inflammation can deplete these cell populations, potentially leading to the development of serious blood conditions such as cancer.

22 May 2013

Nearly 35% of Mexican young adults may have genetic predisposition for obesity, says U of I scientist

As many as 35 percent of Mexican young adults may have a genetic predisposition for obesity, said a University of Illinois scientist who conducted a study at the Universidad Aut-noma de San Luis Potosί.

22 May 2013

Nutritional supplement improves functioning of genes involved in degenerative brain disorders

Widely available in pharmacies and health stores, phosphatidylserine is a natural food supplement produced from beef, oysters, and soy. Proven to improve cognition and slow memory loss, it's a popular treatment for older people experiencing memory impairment.

22 May 2013

PGDx to identify novel kinase targets in collaboration with Blueprint Medicines

Personal Genome Diagnostics Inc., today announced that it will use its proprietary methodologies and expertise in genomic analysis of defined cancer subtypes to identify novel kinase targets in collaboration with Blueprint Medicines.

21 May 2013

Stronger epigenetic changes in estrogen responsive genes linked to postpartum depression

The epigenetic modifications, which alter the way genes function without changing the underlying DNA sequence, can apparently be detected in the blood of pregnant women during any trimester, potentially providing a simple way to foretell depression in the weeks after giving birth, and an opportunity to intervene before symptoms become debilitating.

21 May 2013

Researchers say that receiving cancer radiation therapy late in the day may minimize hair loss

Discovering that mouse hair has a circadian clock - a 24-hour cycle of growth followed by restorative repair - researchers suspect that hair loss in humans from toxic cancer radiotherapy and chemotherapy might be minimized if these treatments are given late in the day.

21 May 2013

Researchers develop new mouse model to discover gene pathways that drive MPNST

University of Minnesota Medical School researchers from the Masonic Cancer Center, University of Minnesota, in partnership with the University's Brain Tumor Program, have developed a new mouse model of malignant peripheral nerve sheath tumors that allow them to discover new genes and gene pathways driving this type of cancer.

21 May 2013

Researchers examine how BRD4 contributes to sustained presence of NF-kappa B in cancer cells

In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.

20 May 2013

Measuring genetic diversity within tumor predicts outcomes of patients with head and neck cancer

A new measure of the heterogeneity - the variety of genetic mutations - of cells within a tumor appears to predict treatment outcomes of patients with the most common type of head and neck cancer.

20 May 2013

Genes News and Research

Potential new treatment approaches for liver diseases

New approach to genetic engineering reduces time and effort needed to insert genes into bacteria

Promising approach to prevent emergence of drug-resistant forms of cancer

Researchers explore targeted therapies for prostate cancer

Wisconsin scientists synthesize potent compounds to curb bacteria that cause staph infections

Cenix BioScience, Debiopharm partner to develop novel therapeutic drug candidates

The Immortality Project awards $2.3M to study near-death experiences, beliefs in afterlife

Viewpoints: Mass. experience may not be true test for national health law; 'Dishonest' campaign by medical device makers

NIH-funded study raises hope for recovery of some adult patients with brain disorder

Viewpoints: Slowing health costs; What causes genetic testing to be so expensive; Iowa governor offers Medicaid supports a 'glimmer of hope'

Rice University computational study tracks regulatory mechanisms of E. coli cells

Caltech biologists show that microRNA-146a protects stem cells during inflammation

Nearly 35% of Mexican young adults may have genetic predisposition for obesity, says U of I scientist

Nutritional supplement improves functioning of genes involved in degenerative brain disorders

PGDx to identify novel kinase targets in collaboration with Blueprint Medicines

Stronger epigenetic changes in estrogen responsive genes linked to postpartum depression

Researchers say that receiving cancer radiation therapy late in the day may minimize hair loss

Researchers develop new mouse model to discover gene pathways that drive MPNST

Researchers examine how BRD4 contributes to sustained presence of NF-kappa B in cancer cells

Measuring genetic diversity within tumor predicts outcomes of patients with head and neck cancer

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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