Immunoglobulin News and Research

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Researchers publish new paper on developing vaccine candidates for Helminthic parasites

Helminthic parasites, like hookworm and liver flukes (schistosomiasis), affect an estimated 1 billion people worldwide. Infection from hookworm and schistosomiasis result in a combined loss of as much as 92 million disability-adjusted life years annually.

17 Aug 2018

Study: IgG3 antibody stops B cells from fighting pathogens in HIV patients

For the first time, scientists have shown that in certain people living with HIV, a type of antibody called immunoglobulin G3 stops the immune system's B cells from doing their normal job of fighting pathogens.

14 Aug 2018

Scientists map regulatory landscape of mouse genome at single-cell resolution

Scientists have completed a major effort to map the regulatory landscape of the mouse genome at a single-cell resolution.

2 Aug 2018

CHOP experts identify new autoimmune disorder along with personalized treatment for young patient

Elijah Patino is a happy, healthy seven-year-old now, but it took a while to get there. For much of his life, he had a mysterious disease that made it painful to eat and painful to play.

2 Aug 2018

Omeros’ OMS721 receives positive opinion from EMA's COMP for treating hematopoietic stem cell transplant

Omeros Corporation announced today that the European Medicines Agency's Committee for Orphan Medicinal Products issued a positive opinion recommending orphan drug designation of OMS721 for treatment in hematopoietic stem cell transplantation.

25 Jul 2018

Researchers discover how antibodies secreted in the gut promote growth of healthy microbiome

Researchers at the RIKEN Center for Integrative Medical Science in Japan have discovered how antibodies secreted in the gut promote the growth of beneficial bacteria.

25 Jul 2018

Researchers find that IgM antibody could protect against HIV-1

A team of scientists from Texas Biomedical Research Institute have homed in on an antibody that could protect against infection with HIV-1.

24 Jul 2018

Study reveals protective potential of new class of antibodies against HIV-1 infection

A group of scientists at Texas Biomedical Research Institute have zeroed in on a new defense against HIV-1, the virus that causes AIDS. Led by Ruth Ruprecht, M.D., Ph.D., the team used an animal model to show for the first time that an antibody called Immunoglobulin M was effective in preventing infection after mucosal AIDS virus exposure.

24 Jul 2018

Allergic responses may help protect the skin against cancer, research suggests

The components of the immune system that trigger allergic reactions may also help protect the skin against cancer, suggest new findings.

18 Jul 2018

Researchers detect presence of IgE antibodies after kidney transplantation

Many donor kidneys that are transplanted are rejected by the recipient within ten years after transplantation.

17 Jul 2018

New study suggests testing urine and blood serum as better way to diagnose myeloma

When it comes to diagnosing a condition in which the plasma cells that normally make antibodies to protect us instead become cancerous, it may be better to look at the urine as well as the serum of our blood for answers, pathologists say.

13 Jul 2018

Children with rare skin conditions often get inconsistent and costly treatments

Researchers from the University of Illinois at Chicago are the first to conduct a large-scale analysis of treatments and outcomes for children with Stevens-Johnson syndrome and toxic epidermal necrolysis, rare skin conditions caused by medications and infections.

10 Jul 2018

Seeing the Unexpected: Regulatory T Cells and Basophils

Dr. Jagadeesh Bayry from INSERM discusses his recent research in the field of immunology, and how T regulatory cells activate, rather than suppress, basophils.

4 Jul 2018

Study: Allergen in red meat linked to plaque buildup in arteries of the heart

A team of researchers says it has linked sensitivity to an allergen in red meat to the buildup of plaque in the arteries of the heart.

14 Jun 2018

Two genes play vital roles in malignant brain cancer

Two genes play important roles for the formation of malignant cancer in the brain. One gene prevents the formation of the tumor, while another gene promotes the tumor. This is shown in a new dissertation at Umeå University, Sweden.

24 May 2018

Alexo Therapeutics marks next significant milestone by initiating ALX148 combination cohorts

Alexo Therapeutics, a clinical-stage immuno-oncology company developing therapies to block the CD47 checkpoint mechanism, today announced it has initiated ALX148 combination dosing with targeted antibody therapies in its Phase 1 clinical program in patients with advanced solid tumors and lymphoma.

17 May 2018

Prenatal test to determine child's rhesus factor found to be reliable, but benefit is unclear

If the blood of a pregnant woman is rhesus-negative and the blood of the fetus is rhesus-positive, the woman may develop antibodies, which can cause severe harm to subsequent children in particular.

16 May 2018

New test developed for accurate and safe diagnosis of peanut allergies

Researchers from the School of Immunology & Microbial Sciences and the Medical Research Council have developed a new test to diagnose peanut allergy.

14 May 2018

New research illustrates how beneficial bacteria establish robust gut colonization

The mammalian gut is warm, moist, and incredibly nutrient-rich--an environment that is perfect for bacterial growth. The communities of "good bacteria" in the gut, commonly referred to as the microbiome, are vital partners for the body, helping to digest fiber, extract nutrients, and prevent various diseases.

4 May 2018

Mother's milk found to have SWAT team of immune cells

Immune cells that are ready to take action against invaders like bacteria have been found in women's breast milk, researchers say.

3 May 2018