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Erectile dysfunction medication found to intensify abdominal aortic aneurysms in mice

In a laboratory study in mice, sildenafil, a commonly used erectile dysfunction medication, was found to worsen abdominal aortic aneurysms, indicating additional research may be needed to determine if the medication may have the same effect on people, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

5 Jan 2022

Efficacy of COVID-19 convalescent plasma therapy in patients with hematological malignancies and COVID-19

Scientists recently demonstrated the efficacy of COVID-19 convalescent plasma therapy in improving the survival rate among patients with B-cell lymphoid malignancy and COVID-19.

5 Jan 2022

Drugs that block mineralocorticoid receptor may help protect bone cells during aging

Drugs we take like prednisone can weaken our bones and so can aging, and scientists working to prevent both have some of the first evidence that the best target may not be the logical one.

5 Jan 2022

Researchers compare survival rates of AML patients treated with two forms of transplantation methods

Acute myeloid leukemia (AML) is a common type of blood cancer that has a relatively low survival rate. It is particularly deadly for patients suffering from refractory and relapsed AML (R/R AML), meaning their cancer has stopped responding to treatment and has returned after a period of remission.

5 Jan 2022

Basic health beliefs and demographics associated with risk factors for cardiovascular disease

Minnesota has the lowest age-adjusted heart disease mortality in the U.S.; yet, African American adults 35 to 63 have nearly double the rate of death from cardiovascular disease, compared to their white counterparts.

5 Jan 2022

Transplant recipients benefit from a COVID-19 vaccine booster

A new preprint research paper posted to the medRxiv* server describes the reduction in humoral immunity in SOTR following vaccination, as well as the improvement with an additional dose of the vaccine.

4 Jan 2022

New gene therapy addresses primary cellular deficit associated with limb-girdle muscular dystrophy 2B

Children's National Hospital experts developed a new pre-clinical gene therapy for a rare disorder, known as limb-girdle muscular dystrophy (LGMD) 2B, that addresses the primary cellular deficit associated with this disease.

4 Jan 2022

Researchers customize finger clip device to provide a noninvasive way for measuring blood pressure

Monitoring a person's blood pressure on a regular basis can help health care professionals with early detection of various health problems such as high blood pressure, which has no warning signs or symptoms.

4 Jan 2022

Unique nanoparticle can deliver genome editing technology to endothelial cells

The lab of Youyang Zhao, PhD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which are cells that line blood vessel walls.

4 Jan 2022

Study adds new evidence supporting the safety of COVID-19 vaccination during pregnancy

Pregnant people who contract COVID-19 have an increased risk of disease severity and death, yet only 31% of pregnant people in the United States had received vaccines as of September 2021.

4 Jan 2022

Empire Discovery Institute collaborates with Novo Nordisk to launch new drug discovery initiative

Empire Discovery Institute entered into a five-year collaborative research partnership with global pharmaceutical company Novo Nordisk A/S to launch LeapRx, a new initiative where EDI and Novo Nordisk will co-invest, incubate and accelerate innovative drug discovery and development projects from its academic partners.

4 Jan 2022

SARS-CoV-2 mRNA vaccine boosters crucial in maintaining neutralizing antibodies in HCPs

Researchers evaluate the effects of a third dose of the BNT162b2 mRNA vaccine on antibody titers and breakthrough infections in healthcare workers.

4 Jan 2022

Sustainable diet can lower the risk of bleeding or blood clots in the brain

The risk of bleeding or blood clots in the brain is lower if your diet is sustainable. This is shown by a new research result from Aarhus University. The results have just been published in the scientific journal Stroke.

4 Jan 2022

A closer look at the relationship between COVID-19 and Alzheimer’s disease

Researchers discuss the findings of previous studies on the role of SARS-CoV-2 infection in the progression of Alzheimer's Disease.

4 Jan 2022

Study offers more insight into respiratory event-related sleep fragmentation and OSA severity

Obstructive sleep apnea is a common breathing disorder causing excessive daytime sleepiness and increasing the risk for cardiovascular disease, hypertension, and stroke.

4 Jan 2022

Exercise performance in vaccinated and unvaccinated individuals previously infected with SARS-CoV-2

A cross-sectional report from Israel demonstrated the protective effect of BNT162b2 mRNA vaccine (Pfizer–BioNTech) even after mild to moderate COVID-19).

4 Jan 2022

New Potocsnak Longevity Institute aims to extend human 'healthspan'

In the not-too-distant future, you'll be able to check into the Human Longevity Laboratory to find out how old you really are, physiologically speaking.

4 Jan 2022

Study finds pan-sarbecovirus nanobodies can enhance development of super-immunity

A new study found that applying pan-sarbecovirus nanobodies shows a strong affinity toward all sarbecovirus clades and neutralized SARS-CoV-2 receptor binding domains

4 Jan 2022

Siemens Healthineers Announces FDA Emergency Use Authorization for CLINITEST® Rapid COVID-19 Antigen Self-Test

The CLINITEST Rapid COVID-19 Antigen Self-Test has received FDA EUA for unsupervised self-testing for the SARS-CoV-2 virus by individuals age 14 and older (or adult-collected samples from individuals ages 2-13).

From Siemens Healthineers 4 Jan 2022

Study finds critical metabolic vulnerability of diffuse large B cell lymphomas

Aggressive and relatively common lymphomas called diffuse large B cell lymphomas (DLBCLs) have a critical metabolic vulnerability that can be exploited to trick these cancers into starving themselves, according to a study from researchers at Weill Cornell Medicine and Cornell's Ithaca campus.

3 Jan 2022

Blood News and Research

Erectile dysfunction medication found to intensify abdominal aortic aneurysms in mice

Efficacy of COVID-19 convalescent plasma therapy in patients with hematological malignancies and COVID-19

Drugs that block mineralocorticoid receptor may help protect bone cells during aging

Researchers compare survival rates of AML patients treated with two forms of transplantation methods

Basic health beliefs and demographics associated with risk factors for cardiovascular disease

Transplant recipients benefit from a COVID-19 vaccine booster

New gene therapy addresses primary cellular deficit associated with limb-girdle muscular dystrophy 2B

Researchers customize finger clip device to provide a noninvasive way for measuring blood pressure

Unique nanoparticle can deliver genome editing technology to endothelial cells

Study adds new evidence supporting the safety of COVID-19 vaccination during pregnancy

Empire Discovery Institute collaborates with Novo Nordisk to launch new drug discovery initiative

SARS-CoV-2 mRNA vaccine boosters crucial in maintaining neutralizing antibodies in HCPs

Sustainable diet can lower the risk of bleeding or blood clots in the brain

A closer look at the relationship between COVID-19 and Alzheimer’s disease

Study offers more insight into respiratory event-related sleep fragmentation and OSA severity

Exercise performance in vaccinated and unvaccinated individuals previously infected with SARS-CoV-2

New Potocsnak Longevity Institute aims to extend human 'healthspan'

Study finds pan-sarbecovirus nanobodies can enhance development of super-immunity

Siemens Healthineers Announces FDA Emergency Use Authorization for CLINITEST® Rapid COVID-19 Antigen Self-Test

Study finds critical metabolic vulnerability of diffuse large B cell lymphomas

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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