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Successful weight-loss intervention helps lower risk of severe complications from COVID-19

A Cleveland Clinic study shows that among patients with obesity, prior weight loss achieved with bariatric surgery was associated with a 60% lower risk of developing severe complications from COVID-19 infection. The research was published in the journal JAMA Surgery.

30 Dec 2021

Exploring the importance of selenium in COVID-19 patients

In a new study, researchers reviewed research on the role that selenium could play in protecting individuals against coronavirus disease 2019.

29 Dec 2021

Study shows fully vaccinated individuals preserve cross-neutralizing memory B-cells against SARS-CoV-2 Omicron variant

A new study found increases in resting memory B cell subsets showed strong cross-reactivity against several variants, including Omicron.

29 Dec 2021

3-dose vaccines deemed ultrapotent against diverse and highly transmissible SARS-CoV-2 Omicron and other variants

A new study found that the presence of a subset of antibodies with broad neutralizing activities against all circulating variants of concern in the three-dose vaccines' memory B-derived antibody repertoire suggests that the Omicron/future variants infection may elicit selective and rapid recall of humoral responses, conferring secondary protection directed by memory etched in the immune system.

29 Dec 2021

New strategy to create a cheap and rapid COVID-19 test based on isothermal amplification

Russian researchers have developed a strategy to create a cheap and rapid COVID-19 test based on isothermal amplification. According to their publication in Applied Biochemistry and Microbiology, use of this strategy will make it possible to create universal test systems for any of the COVID-19 variants.

29 Dec 2021

Human iPSC-derived fallopian tube organoids reveal the origins of common ovarian cancer

Stem cell scientists have revealed the origins of a common ovarian cancer by modeling fallopian tube tissues, allowing them to characterize how a genetic mutation puts women at high risk for this cancer.

29 Dec 2021

Combination of rifampicin and resveratrol helps stop dementia, finds study

Dementia is thought to occur when proteins called amyloid-β, tau, and α-synuclein accumulate in the brain and form oligomers. A research group from the Department of Translational Neuroscience, Osaka City University Graduate School of Medicine, had previously shown in a study using mice that the antibiotic rifampicin removes oligomers from the brain and improves cognitive function.

29 Dec 2021

Study sheds light on how the immune system behaves during pregnancy

Pregnancy is a challenge for the mother's immune system from the outset. Half of the genes in the fetus are foreign to her body.

29 Dec 2021

Pregnant women should not delay COVID-19 vaccination until late pregnancy, study suggests

COVID-19 vaccination of expectant mothers elicits levels of antibodies to the SARS-CoV-2 outer "spike" protein at the time of delivery that don't vary dramatically with the timing of vaccination during pregnancy and thus don't justify delaying vaccination, according to a study from researchers at Weill Cornell Medicine and NewYork-Presbyterian.

28 Dec 2021

Pre-existing immunity against influenza can lower SARS-CoV-2 infection burden and spread

A recent study by a team of European researchers demonstrated how antibodies induced by currently circulating influenza A H1N1 strains can cross-react with the important part of the SARS-CoV-2 spike glycoprotein that interacts with the human cell receptor. Their paper is currently available on the medRxiv* preprint server while it undergoes peer review.

28 Dec 2021

Structural blueprint of nanoparticles developed to target neutrophils responsible for acute lung inflammation

The COVID-19 pandemic highlighted the devastating impact of acute lung inflammation (ALI), which is part of the acute respiratory distress syndrome (ARDS) that is the dominant cause of death in COVID-19.

28 Dec 2021

Excessive intake of simple sugar in adolescents could be a risk factor of psychiatric disorders

There has been a remarkable increase in intake of simple sugar (sucrose, isomerized sugar (corn syrup)) from beverages and diets in modern society. The intake of simple sugars in adolescents in which mental disorders frequently occur is higher than any other generations.

28 Dec 2021

Cancer patients who had breakthrough COVID-19 remain at high risk for hospitalization, death

The first study to evaluate the clinical characteristics and outcomes of fully vaccinated patients with cancer who had breakthrough COVID-19 infections indicates they remained at high risk for hospitalization and death.

26 Dec 2021

LJI researchers discover how loss of TET enzymes can lead to B cell lymphoma

Scientists at the La Jolla Institute for Immunology have uncovered how loss of TET enzymes can lead to B cell lymphoma. Their research, published in Nature Immunology, could potentially open opportunities for designing drug treatment strategies to target malignant cells in many cancers.

24 Dec 2021

Blood News and Research

Successful weight-loss intervention helps lower risk of severe complications from COVID-19

Exploring the importance of selenium in COVID-19 patients

Study shows fully vaccinated individuals preserve cross-neutralizing memory B-cells against SARS-CoV-2 Omicron variant

3-dose vaccines deemed ultrapotent against diverse and highly transmissible SARS-CoV-2 Omicron and other variants

New strategy to create a cheap and rapid COVID-19 test based on isothermal amplification

Human iPSC-derived fallopian tube organoids reveal the origins of common ovarian cancer

Combination of rifampicin and resveratrol helps stop dementia, finds study

Study sheds light on how the immune system behaves during pregnancy

Pregnant women should not delay COVID-19 vaccination until late pregnancy, study suggests

Pre-existing immunity against influenza can lower SARS-CoV-2 infection burden and spread

Structural blueprint of nanoparticles developed to target neutrophils responsible for acute lung inflammation

Excessive intake of simple sugar in adolescents could be a risk factor of psychiatric disorders

Cancer patients who had breakthrough COVID-19 remain at high risk for hospitalization, death

LJI researchers discover how loss of TET enzymes can lead to B cell lymphoma

Study hints subtle differences in the quality of immune response based on COVID-19 severity

Study uncovers new details behind inflammation that promotes cardiovascular disease

Scientists identify a new Achilles' heel of influenza virus

Inhaled CBD shrinks glioblastoma’s size in an animal model

Are our bowel habits written in our DNA?

SARS-CoV-2 spreads through cell-to-cell transmission, study finds

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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