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High levels of blood cholesterol increase risk of AD and heart disease

Researchers at the Linda Crnic Institute for Down Syndrome and the University of Colorado School of Medicine have found that a single mechanism may underlie the damaging effect of cholesterol on the brain and on blood vessels.

16 Apr 2013

Research: Gene expression signature may increase risk of tumor recurrence or spread prostate cancer

A team led by Massachusetts General Hospital researchers has identified a genetic signature that appears to reflect the risk of tumor recurrence or spread in men surgically treated for prostate cancer.

16 Apr 2013

First Edition: April 16, 2013

Today's headlines include coverage of the Supreme Court oral arguments regarding whether patents should be granted for human genes.

16 Apr 2013

Monell Center molecular neurobiologist to receive Ajinomoto Award for Young Investigators in Gustation

Monell Center molecular neurobiologist Peihua Jiang, PhD, is the 2013 recipient of the Ajinomoto Award for Young Investigators in Gustation, an annual award presented by the Association for Chemoreception Sciences (AChemS) to an exceptional junior scientist who is a rising leader in the field of gustation.

16 Apr 2013

Viewpoints: Editorial boards offer advice to Supreme Court on gene patents

On Monday, the Supreme Court is scheduled to hear argument about that decision in Association for Molecular Pathology v. Myriad Genetics.

16 Apr 2013

Supreme Court to decide crucial case on patenting human genes

The high court will hear a challenge to Myriad Genetics' patent of breast and ovarian cancer genes in a case that will affect the future of biomedical research, the fight against diseases like breast and ovarian cancer and a multi-billion dollar biotechnology business.

16 Apr 2013

Junk DNA plays important role in brain development

Specific DNA once dismissed as junk plays an important role in brain development and might be involved in several devastating neurological diseases, UC San Francisco scientists have found.

16 Apr 2013

Researchers find three new regions of genome that influence obesity in people of African descent

The largest genetic search for "obesity genes" in people of African ancestry has led to the discovery of three new regions of the human genome that influence obesity in these populations and others.

16 Apr 2013

Researchers discover 14 new genetic variations associated with heart rate

Through a collaborative genome-wide study on individuals, researchers have discovered 14 new genetic variations that are associated with heart rate.

15 Apr 2013

First Edition: April 15, 2013

Today's headlines include reports about the Medicare provisions in the budget plan released last week by President Barack Obama as well as previews of the Supreme Court's consideration of arguments regarding whether human genes can be patented.

15 Apr 2013

Researchers identify gene mutations responsible for subtype of childhood brain tumor

The St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project has identified mutations responsible for more than half of a subtype of childhood brain tumor that takes a high toll on patients.

15 Apr 2013

Researchers study gene that contributes to late-onset Alzheimer's disease in African-Americans

Researchers at Mayo Clinic in Florida participated in a nationwide study that found minor differences between genes that contribute to late-onset Alzheimer's disease in African-Americans and in Caucasians.

15 Apr 2013

Johns Hopkins researchers to highlight progress in genetic research at international meeting

Johns Hopkins genetics researchers Aravinda Chakravarti, Ph.D., and David Valle, M.D., will each present at the joint conference of the Human Genome Meeting 2013 and the 21st International Congress of Genetics.

15 Apr 2013

Scientists use mouse model to identify novel cell surface marker on mammary gland stem cells

Stem cells are different from all other cells in our body because they retain the remarkable genetic plasticity to self-renew indefinitely as well as develop into cell types with more specialized functions. However, this remarkable self-renewal capacity comes with a price, as stem cells can become seeds of cancer.

15 Apr 2013

Novel nanoparticle-based approach enables more efficient delivery of siRNA drugs

New classes of drugs that can silence specific genes, such as small interfering RNAs (siRNAs), offer great therapeutic potential. But the specific delivery of siRNAs to target cells to exert their effects remains a significant challenge. A novel nanoparticle-based approach that enables more efficient delivery of siRNA drugs is presented in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

12 Apr 2013

Study shows more women develop chronic low back pain, sciatica than men

More women than men develop chronic low back pain and sciatica. The explanation may lie with a gene variant that plays into the body's pain regulation.

12 Apr 2013

Researchers use metagenomics to identify the cause of outbreaks of bacterial infection

Researchers have been able to reconstruct the genome sequence of an outbreak strain of Shiga-toxigenic Escherichia coli (STEC), which caused over 50 deaths in Germany, using an approach known as metagenomics which bypasses the need for growing bacteria in the lab.

12 Apr 2013

Sanofi launches large-scale production of artemisinin for malaria

Twelve years after a breakthrough discovery in his University of California, Berkeley, laboratory, professor of chemical engineering Jay Keasling is seeing his dream come true.

12 Apr 2013

ATSP-9172 exhibits on-target binding activity in human prostate cancer model

Aileron Therapeutics, Inc. today announced new preclinical data demonstrating that ATSP-9172, its Stapled Peptide inhibitor of HIF-1α-dependent transcription, exhibits on-target binding activity, favorable pharmacokinetic properties and potent in vivo efficacy in a human prostate cancer model.

12 Apr 2013

Antipsychotics seemed to normalize gene expression pattern in people with bipolar disorder: Study

Every day, millions of people with bipolar disorder take medicines that help keep them from swinging into manic or depressed moods.

12 Apr 2013

Genes News and Research

High levels of blood cholesterol increase risk of AD and heart disease

Research: Gene expression signature may increase risk of tumor recurrence or spread prostate cancer

First Edition: April 16, 2013

Monell Center molecular neurobiologist to receive Ajinomoto Award for Young Investigators in Gustation

Viewpoints: Editorial boards offer advice to Supreme Court on gene patents

Supreme Court to decide crucial case on patenting human genes

Junk DNA plays important role in brain development

Researchers find three new regions of genome that influence obesity in people of African descent

Researchers discover 14 new genetic variations associated with heart rate

First Edition: April 15, 2013

Researchers identify gene mutations responsible for subtype of childhood brain tumor

Researchers study gene that contributes to late-onset Alzheimer's disease in African-Americans

Johns Hopkins researchers to highlight progress in genetic research at international meeting

Scientists use mouse model to identify novel cell surface marker on mammary gland stem cells

Novel nanoparticle-based approach enables more efficient delivery of siRNA drugs

Study shows more women develop chronic low back pain, sciatica than men

Researchers use metagenomics to identify the cause of outbreaks of bacterial infection

Sanofi launches large-scale production of artemisinin for malaria

ATSP-9172 exhibits on-target binding activity in human prostate cancer model

Antipsychotics seemed to normalize gene expression pattern in people with bipolar disorder: Study

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