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The global succinylation and protein abundance in SARS-CoV-2–infected cells

Researchers assessed the global succinylation of SARS-CoV-2-infected host cells.

14 Jul 2022

The disease burden and clinical severity of the SARS-CoV-2 Omicron BA.2 sublineage outbreak in Shanghai

Researchers estimated the severity and burden of COVID-19 in a recent outbreak in Shanghai, China.

14 Jul 2022

Lipids in breastmilk may protect against metabolic disease later in life

A new study examines the lipid content in breastmilk and its association with NCDs later in life.

13 Jul 2022

Study identifies a protein that plays key role in protecting the gastrointestinal tract from inflammation

A protein called Zbtb46, expressed by specialized immune cells, has a major role in protecting the gastrointestinal tract from excessive inflammation, according to a study from researchers at Weill Cornell Medicine.

13 Jul 2022

Doggybone DNA COVID-19 vaccine can effectively neutralize SARS-CoV-2 variants

Researchers assessed the efficacy of the novel SARS-CoV-2 doggybone deoxyribonucleic acid (DNA) vaccine.

13 Jul 2022

Detection of SARS-CoV-2 variants in aircraft wastewater

Researchers detect SARS-CoV-2 variants in the wastewater of aircrafts

12 Jul 2022

How do symptom burden and viral kinetics differ between healthy, vaccinated adults infected with either Delta, Omicron BA.1, or BA.2?

Researchers assessed the symptom profiles present in SARS-CoV-2 Delta, Omicron BA1. and BA.2-infected patients.

12 Jul 2022

Researchers create a comprehensive map of how complex networks of genes function together

Using new technologies to study thousands of genes simultaneously within immune cells, researchers at Gladstone Institutes, UC San Francisco (UCSF), and Stanford School of Medicine have created the most detailed map yet of how complex networks of genes function together.

11 Jul 2022

SARS-CoV-2 spike protein downregulates ACE2 expression

In a new study, researchers observed the downregulation of ACE2 by SARS-CoV-2.

11 Jul 2022

Study highlights need to prioritize immunocompromised COVID patients

In a recent Morbidity and Mortality Weekly Report (MMWR) published on the United States Center for Disease Control and Prevention (US-CDC) website, researchers evaluated whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected immunocompromised individuals are at a higher risk of intensive care unit (ICU) admission and death.

10 Jul 2022

The putative impact of vitamin D receptor gene polymorphisms on SARS-CoV-2 infection among different variants

Researchers assessed the association between SARS-CoV-2 variants and the vitamin D receptor gene.

8 Jul 2022

Discovery of multiple new SARS-CoV-2 MPro inhibitors

In a recent study posted to the bioRxiv* preprint server, researchers performed an extensive library docking for new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) covalent and non-covalent inhibitors.

8 Jul 2022

Researchers find a way to kill recurring prostate cancer with a lot of iron

Prostate cancer can come back from common hormone deprivation therapy with a vengeance and no clear treatment option, but scientists have early evidence that one way to kill these recurring cancer cells may be with a lot of iron.

7 Jul 2022

2022 monkeypox presents with new symptoms

In a recent study published in The Lancet Infectious Diseases, researchers described the clinical and demographical characteristics of monkeypox virus infections among individuals attending sexual health centers in the United Kingdom (UK).

6 Jul 2022

Chicoric acid a potential candidate for COVID-19 treatment

An article under review in the Scientific Reports journal and currently available on the Research Square* preprint server reports on chicoric acid (CA) as a potential inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Jul 2022

The role of myostatin in female fertility

A new study discusses some of the key functions of myostatin in female reproductive health and disease.

6 Jul 2022

Beyond COVID-19: the potential future applications of mRNA vaccines

Researchers described the production, mechanisms, and potential applications of mRNA vaccines.

6 Jul 2022

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Researchers investigated the intrahost evolution and genetic diversity of the SARS-CoV-2 B.1.517 variant in an immunosuppressed person with chronic COVID-19.

6 Jul 2022

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

In a recent study posted to the medRxiv* pre-print server, researchers developed a mechanistic mathematical model to predict the course of vaccine-induced immunity in healthy and immunosuppressed patients for the long term, exceeding the time frames for which clinical data is currently available.

5 Jul 2022