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Novel microneedle patch can immediately stop bleeding after traumatic injury

A soldier suffers a serious gunshot wound on a remote battlefield or a machinist has a work accident and gets stuck in traffic on the way to the hospital. Secondary, uncontrolled bleeding from traumatic injury is the leading cause of death of Americans from ages one to 46.

24 Jan 2023

Novel amyloid protein discovered from canine mammary tumors

A collaboration led by scientists at Tokyo University of Agriculture and Technology (TUAT), Japan, has discovered a novel amyloid protein from canine mammary tumors.

24 Jan 2023

Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a Master’s student at the University of Glasgow (UoG) to undertake a research project on USP30, a DUB implicated in neurodegenerative, renal, and cardiovascular diseases.

From Ubiquigent Limited 23 Jan 2023

Phase I trial results from AdaptVac's COVID capsid virus-like particle vaccine

In a recent study published in The Lancet Microbe journal, researchers described the effectiveness of a modular capsid virus-like coronavirus disease 2019 (COVID-19) vaccination.

22 Jan 2023

Senolytics could be a beneficial therapeutic for COVID neuropathology

Researchers assess the effectiveness of multiple senolytic interventions in removing senescent cells in aged human brain organoids.

22 Jan 2023

Study reveals the mechanism through which Sirtuin 7 protein suppresses thermogenesis in mice

Mammals convert the energy stored in adipose (fat) tissue into heat via a process known as thermogenesis.

20 Jan 2023

InDevR raises $9 million in series B financing and partners with bioMérieux

New partnerships will drive the commercial expansion of InDevR’s game-changing solutions for vaccines and biotherapeutics.

20 Jan 2023

Are dysregulated metabolism and inflammation contributing factors to the ongoing symptoms in long-term COVID-19 syndrome patients?

Researchers reported that dysregulation in energy metabolism and inflammation could contribute to long-term COVID-19 syndrome.

19 Jan 2023

How does the brain change with age?

Researchers discussed cellular hallmarks of brain aging and therapeutic interventions to rejuvenate cognitive brain functions.

19 Jan 2023

Partial genetic reprogramming might extend lifespan and reverse aging in old mice

Researchers performed age-reversing experiments, in vivo and in vitro, in progeroid mice using gene therapy.

19 Jan 2023

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Researchers explored how mutations in emergent SARS-CoV-2 variants affect viral function, human immunity, and recognition by therapeutic antibodies.

19 Jan 2023

Exploring bioinformatics approach for evaluating binding affinities of probable COVID-19 therapeutic decoys

Researchers developed a computational workflow based on molecular dynamic (MD) simulations and artificial neural network (ANN) to assess the SARS-CoV-2 spike (S) protein receptor-binding domain (RBD)-human angiotensin-converting enzyme 2 (hACE2) binding affinities of SARS-CoV-2 variants.

17 Jan 2023

S. aureus enhances replication of SARS-CoV-2 in vitro through the bacterial iron-regulated surface determinant protein A

Researchers assessed the impact of Staphylococcus aureus (S. aureus) on SARS-CoV-2 replication.

17 Jan 2023

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

Researchers investigated the ability of kinetin (N6-furfurylaminopurine, MB-905) to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proliferation in vitro.

17 Jan 2023

The FDA further expands collaboration with CN Bio to evaluate the PhysioMimix Multi-organ microphysiological system

Expansion of five-year collaboration broadens established Organ-on-a-chip research demonstrating advanced performance of the PhysioMimix MPS.

From CN Bio 17 Jan 2023

Researchers report that vectored expression of a high-affinity ACE2 microbody protein establishes a high degree of protection from SARS-CoV-2

Researchers evaluated the use of receptor decoys for SARS-CoV-2 based on soluble forms of ACE2 for immunological prophylaxis and management of COVID-19 through the use of AAV vectors.

16 Jan 2023

in vitro News and Research

Novel microneedle patch can immediately stop bleeding after traumatic injury

Novel amyloid protein discovered from canine mammary tumors

Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

Phase I trial results from AdaptVac's COVID capsid virus-like particle vaccine

Senolytics could be a beneficial therapeutic for COVID neuropathology

Study reveals the mechanism through which Sirtuin 7 protein suppresses thermogenesis in mice

InDevR raises $9 million in series B financing and partners with bioMérieux

Are dysregulated metabolism and inflammation contributing factors to the ongoing symptoms in long-term COVID-19 syndrome patients?

How does the brain change with age?

Partial genetic reprogramming might extend lifespan and reverse aging in old mice

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Exploring bioinformatics approach for evaluating binding affinities of probable COVID-19 therapeutic decoys

S. aureus enhances replication of SARS-CoV-2 in vitro through the bacterial iron-regulated surface determinant protein A

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

The FDA further expands collaboration with CN Bio to evaluate the PhysioMimix Multi-organ microphysiological system

Researchers report that vectored expression of a high-affinity ACE2 microbody protein establishes a high degree of protection from SARS-CoV-2

Researchers develop innovative STAb therapy for a type of leukemia

Should we be getting used to the idea of eating insects?

Targeting T cell iron metabolism may offer a new approach for treating lupus

Valuable tool reveals the connections between gut microbes and the brain

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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