Genes News and Research

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New genome-wide association study sheds light on the underlying biology of polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) has been passed down in many families for generations -- causing reproductive and metabolic health problems for millions of women around the world. Yet, its cause remains unknown despite more than 80 years of research since the disorder was first described in 1935.

20 Aug 2015

Discovery could influence future research on respiratory failure associated with diabetes

Previous studies have shown that diabetes adversely affects breathing and respiratory function. However, in the past, researchers have not differentiated diaphragm muscle cells and the muscle cells of limb skeletal muscle in their studies. Now, researchers from the University of Missouri have found that diaphragm muscle cells and other skeletal muscle cells behave differently--a finding that could influence future research on respiratory ailments associated with diabetes.

20 Aug 2015

New study uses donor sample to evaluate how self-identification measures intersect with genetics

For years, medicine has relied on self-reported race/ethnicity as the basis of an array of decisions, from risk for disease to matching organ donors. Now, a study led by researchers at UC San Francisco has found that when that information matters most - in connecting bone marrow donors to patients - the format of the questions may determine how well the answers actually correspond to their genes.

20 Aug 2015

Scientists create membrane capable of detecting organisms that trigger diarrhea, intestinal problems

A group of scientists from the Institute of Ecology and the Faculty of Medicine of the National University of Mexico, created a membrane capable of simultaneously detecting numerous organisms in the water or food that cause diarrhea and intestinal problems. This health problem annually kills 760 000 children under the age of five, according to the World Health Organization.

20 Aug 2015

Sex signals not always passed on to offspring

Sending signals to the opposite sex isn't always a trait that's passed on to animals' offspring, according to new research conducted at Michigan State University.

20 Aug 2015

Researchers reveal new pathway that governs proper sorting of essential synaptic proteins in neurons

Genetic analysis of human patients has shown that mutations in genes involved in synaptic communication can drive neuropsychiatric and neurological diseases such as autism spectrum disorder and Alzheimer's disease.

20 Aug 2015

Researchers uncover genetic circuit involved in obesity

Like many other conditions, obesity is caused by an interplay between genetic and environmental factors. While efforts to combat the obesity epidemic will need to include changes in diet and exercise, insights into the genes involved may also help with prevention and treatment.

20 Aug 2015

New initiative aims to collect samples from schizophrenia patients across the globe

Institute for Molecular Medicine Finland (FIMM) at the University of Helsinki and The Stanley Center for Psychiatric Research at Broad Institute, together with its international partners, are initiating major new sample collections in several regions and countries.

19 Aug 2015

Further understanding of genetic influence in ALS to be explored in new partnership

Biogen, the ALS Association and Columbia University Medical Center (CUMC) today announced a new collaboration to better understand the differences and commonalities in the ALS disease process and how genes influence the clinical features of the disease.

19 Aug 2015

Discovery allows study of naturally occurring forms of HCV in the lab

Worldwide, 185 million people have chronic hepatitis C. Since the late 1980s, when scientists discovered the virus that causes the infection, they have struggled to find ways to grow it in human cells in the lab -- an essential part of learning how the virus works and developing new effective treatments.

19 Aug 2015

LINE-1 jumping gene unusually active in gastrointestinal cancer

Results of a trio of studies done on human cancer tissue biopsies have added to growing evidence that a so-called jumping gene called LINE-1 is active during the development of many gastrointestinal cancers.

19 Aug 2015

Johns Hopkins scientists develop novel fish embryo technique to identify potential new treatments for diabetes

In experiments with 500,000 genetically engineered zebrafish embryos, Johns Hopkins scientists report they have developed a potentially better and more accurate way to screen for useful drugs, and they have used it to identify 24 drug candidates that increase the number of insulin-producing cells in the pancreas.

19 Aug 2015

First patient enrolled in Phase II trial of ImmunoPulse IL-12 and pembrolizumab combination therapy

OncoSec Medical Incorporated, a company developing DNA-based intratumoral cancer immunotherapies, today announced enrollment of the first patient into the Phase II Investigator Sponsored Trial led by the University of California, San Francisco to assess the anti-tumor activity, safety, and tolerability of the combination of OncoSec's investigational therapy, ImmunoPulse IL-12, and Merck's approved anti-PD-1 agent, KEYTRUDA (pembrolizumab), in patients with unresectable metastatic melanoma.

18 Aug 2015

Researchers describe central role of mTOR in ageing and age-related diseases

For some, TOR may bring to mind a Celtic mountain or perhaps an Internet privacy group. In the world of molecular biology it's a cellular pathway that's found in everything from yeast to mammals.

18 Aug 2015

Study reports results of genetic testing for 22 genetic causes of neonatal diabetes

Over a 10 year period, the time that babies receive genetic testing after being diagnosed with diabetes has fallen from over four years to under two months. Pinpointing the exact genetic causes of sometimes rare forms of diabetes is revolutionising healthcare for these patients.

18 Aug 2015

Dr. Samadi's Prostate Cancer Center now offers Oncotype DX genetic test

Revolutionary genetic test, Oncotype DX from Genomic Health, is now offered at Dr. Samadi's Prostate Cancer Center in New York City.

18 Aug 2015

New research explores underlying mechanisms by which bacteria acquire antibiotic resistance genes

A scientific peek into bacteria boudoirs is revealing how "sex" among disease-causing microbes can lead different species or strains to become resistant to antibiotic medications.

18 Aug 2015

Studies show jumping genes more active during development of gastrointestinal cancers

18 Aug 2015

‘Medical foods’ for patients with rare IEMs may cause harm when not carefully managed

Many "medical foods" are designed to help manage patients with rare inborn errors of metabolism (IEMs), and can help prevent serious and life-threatening complications. However, such special foods may cause harm in some patients when their use is not carefully monitored and managed, according to a research team led by scientists at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health.

14 Aug 2015

NSF awards EAGER grant to expand use of temperature-activated protein switches in neurons

Troy Zars, Mirela Milescu, and Lorin Milescu, faculty members of the Division of Biological Sciences and the Interdisciplinary Neuroscience Program at the University of Missouri, have been awarded an Early Concept Grant for Exploratory Research (EAGER) from the National Science Foundation to expand the use of a temperature-activated protein switches in neurons. The new technology could lead to a better understanding of brain disorders in humans.

14 Aug 2015

Genes News and Research

New genome-wide association study sheds light on the underlying biology of polycystic ovary syndrome

Discovery could influence future research on respiratory failure associated with diabetes

New study uses donor sample to evaluate how self-identification measures intersect with genetics

Scientists create membrane capable of detecting organisms that trigger diarrhea, intestinal problems

Sex signals not always passed on to offspring

Researchers reveal new pathway that governs proper sorting of essential synaptic proteins in neurons

Researchers uncover genetic circuit involved in obesity

New initiative aims to collect samples from schizophrenia patients across the globe

Further understanding of genetic influence in ALS to be explored in new partnership

Discovery allows study of naturally occurring forms of HCV in the lab

LINE-1 jumping gene unusually active in gastrointestinal cancer

Johns Hopkins scientists develop novel fish embryo technique to identify potential new treatments for diabetes

First patient enrolled in Phase II trial of ImmunoPulse IL-12 and pembrolizumab combination therapy

Researchers describe central role of mTOR in ageing and age-related diseases

Study reports results of genetic testing for 22 genetic causes of neonatal diabetes

Dr. Samadi's Prostate Cancer Center now offers Oncotype DX genetic test

New research explores underlying mechanisms by which bacteria acquire antibiotic resistance genes

Studies show jumping genes more active during development of gastrointestinal cancers

‘Medical foods’ for patients with rare IEMs may cause harm when not carefully managed

NSF awards EAGER grant to expand use of temperature-activated protein switches in neurons

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