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Enhancing residence time improves drug effectivity: Study

Studies led by Stony Brook University professor of chemistry Peter J. Tonge indicate that modifications that enhance the time a drug remains bound to its target, or residence time, may lead to better diagnostic and therapeutic agents.

26 Apr 2010

Feature: Patient coding and the ratings game

In this week's BMJ, Nigel Hawkes, freelance journalist and Director of Straight Statistics, a campaign for the better use of statistical data, investigates how the way that patients are allocated diagnostic codes by a hospital can have a big effect on a hospital's performance.

26 Apr 2010

FDA clears Osmetech's eSensor Thrombophilia Risk Test

Osmetech, plc today announced that the US Food and Drug Administration (FDA) has cleared the eSensor® Thrombophilia Risk Test (TRT), a multiplexed molecular diagnostic test for four genetic markers associated with thrombosis. The panel includes Factor V Leiden, Factor II Prothrombin, MTHFR 677 and MTHFR 1298 in a single test panel.

26 Apr 2010

Canadian Red Cross expands Malaria Bites campaign

This World Malaria Day, the Canadian Red Cross is ramping up their fight against malaria. The Canadian Red Cross is expanding their successful Malaria Bites campaign, which has already seen the distribution of six million bed nets, to include additional health interventions and treatment options.

26 Apr 2010

Novel clinical research approaches for rapidly identifying and preventing congenital cardiovascular defects

Structural and functional congenital cardiovascular abnormalities present at birth are the leading source of all congenital defects encountered in live births. Nearly half a million children in the United States have structural heart problems ranging in severity from relatively simple issues, such as small holes between chambers of the heart, to very severe malformations, including complete absence of one or more chambers or valves.

24 Apr 2010

ACP to provide physicians, patients with evidence-based recommendations for clinical problems

Building on its existing foundation of clinical and public policies, the American College of Physicians announced plans to provide physicians and patients with evidence-based recommendations for specific interventions for a variety of clinical problems.

24 Apr 2010

AlloMap molecular expression test reduces need for invasive heart-muscle biopsies

Monitoring rejection in heart transplantation patients with a simple blood test co-developed by NewYork-Presbyterian Hospital/Columbia University Medical Center physician-scientist Dr. Mario Deng in 2005 can safely reduce their need for invasive heart-muscle biopsies, a new study has found.

24 Apr 2010

Research roundup: Arthritis racial disparities, hospital mortality data, voters on long-term care

Differences In The Prevalence And Impact Of Arthritis Among Racial/Ethnic Groups In The United States, National Health Interview Survey, 2002, 2003, and 2006 - "Blacks and Hispanics were approximately 1.3 times as likely as whites to have activity limitation, 1.8 to 1.9 times as likely to have severe joint pain, and 1.6 to 1.7 times as likely to have work limitation," caused by arthritis.

24 Apr 2010

Environmental factors may play bigger role in tumor development: BIDMC study

It is an accepted fact that genetics play a key role in a person's susceptibility to cancer, and that throughout life, mutations can cause damage to tumor suppressor genes further increasing the chances of developing cancerous tumors.

24 Apr 2010

Rapid diagnostic tests for malaria

A new evaluation of malaria rapid diagnostic tests will help health workers quickly identify which patients have the disease and need immediate treatment, putting into action recent World Health Organization recommendations to confirm diagnosis of malaria before treatment.

24 Apr 2010

New initiative to address safety problems associated with external infusion pumps

The U.S. Food and Drug Administration today announced a new initiative to address safety problems associated with external infusion pumps, which are devices that deliver fluids, including nutrients and medications, into a patient's body in a controlled manner.

24 Apr 2010

IDEXX Laboratories' first-quarter 2010 revenues increase 14% to $268.5M

IDEXX Laboratories, Inc., today reported that revenues for the first quarter of 2010 increased 14% to $268.5 million, from $236.5 million for the first quarter of 2009. Organic revenue growth, as defined below, was 9%. Earnings per diluted share for the quarter ended March 31, 2010 increased 28% to $0.55, compared to $0.43 for the same period in the prior year.

23 Apr 2010

City of Manchester, Anthem Blue Cross and Blue Shield enhance Compass SmartShopper Program

Citing strong interest and engagement from city employees as well as requests from school district members, the city of Manchester and Anthem Blue Cross and Blue Shield in New Hampshire announced today enhancements to the innovative Compass SmartShopper Program as well as the addition of Manchester school district employees to the project.

23 Apr 2010

Coronary CTA can be alternative, non-invasive diagnostic imaging test to triage CAD patients: Study

Non-invasive coronary computed tomography angiography is a cost-effective alternative to invasive cardiac catheterization in the care of patients who have positive stress test results but a less than 50 percent chance of actually having significant coronary artery disease, according to a study in the May issue of the American Journal of Roentgenology.

23 Apr 2010

UIC College of Dentistry awarded $10M federal grant to upgrade research facilities

The University of Illinois at Chicago College of Dentistry has received a $10 million federal grant to transform its research facilities into a state-of-the-art clinical and translational research center.

23 Apr 2010

Potential new early cancer detection method using engineered gold nanoparticles

University of Missouri School of Medicine scientists explain a potentially new early cancer detection and treatment method using nanoparticles created at MU in an article published in the Proceedings of the National Academy of Sciences. The article illustrates how engineered gold nanoparticles tied to a cancer-specific receptor could be targeted to tumor cells to treat prostate, breast or lung cancers in humans.

23 Apr 2010

Genentech submits sBLA for Herceptin plus chemotherapy for advanced HER2-positive stomach cancer

Genentech, Inc., a wholly owned member of the Roche Group, announced today that the company submitted a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) for Herceptin® (trastuzumab) plus chemotherapy in people with advanced, HER2-positive adenocarcinoma of the stomach, including gastroesophageal junction cancer.

23 Apr 2010

NeoStem signs Collaborative Research Agreement with ImmuneRegen BioSciences

NeoStem, Inc., an international biopharmaceutical company with operations in the U.S. and China and ImmuneRegen BioSciences, Inc., a wholly owned subsidiary of IR BioSciences Holdings, Inc., announced today that they have entered into a Collaborative Research Agreement, focused on the development of an advanced, adult human stem cell product.

23 Apr 2010

Removable methyl groups on specific genes of autistic individuals that led to gene silencing identified

A new study by researchers at The George Washington University School of Medicine and Health Sciences' Department of Biochemistry and Molecular Biology raises hope that autism may be more easily diagnosed and that its effects may be more reversible than previously thought.

22 Apr 2010

Understanding genetic causes of mental retardation

This remarkable publication focuses on the importance of genetics in mental retardation, investigating the extent to which molecular diagnostic capability and the understanding of genetic causes have improved over recent years. As a result, clinical evaluation and diagnostic laboratory practice are now undergoing an unprecedented period of change.

22 Apr 2010

Diagnostic News and Research

Enhancing residence time improves drug effectivity: Study

Feature: Patient coding and the ratings game

FDA clears Osmetech's eSensor Thrombophilia Risk Test

Canadian Red Cross expands Malaria Bites campaign

Novel clinical research approaches for rapidly identifying and preventing congenital cardiovascular defects

ACP to provide physicians, patients with evidence-based recommendations for clinical problems

AlloMap molecular expression test reduces need for invasive heart-muscle biopsies

Research roundup: Arthritis racial disparities, hospital mortality data, voters on long-term care

Environmental factors may play bigger role in tumor development: BIDMC study

Rapid diagnostic tests for malaria

New initiative to address safety problems associated with external infusion pumps

IDEXX Laboratories' first-quarter 2010 revenues increase 14% to $268.5M

City of Manchester, Anthem Blue Cross and Blue Shield enhance Compass SmartShopper Program

Coronary CTA can be alternative, non-invasive diagnostic imaging test to triage CAD patients: Study

UIC College of Dentistry awarded $10M federal grant to upgrade research facilities

Potential new early cancer detection method using engineered gold nanoparticles

Genentech submits sBLA for Herceptin plus chemotherapy for advanced HER2-positive stomach cancer

NeoStem signs Collaborative Research Agreement with ImmuneRegen BioSciences

Removable methyl groups on specific genes of autistic individuals that led to gene silencing identified

Understanding genetic causes of mental retardation

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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