Embryo News and Research

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New technology tracks millions of cells simultaneously during organ development

Thanks to a new technology called Moscot ("Multi-Omics Single-Cell Optimal Transport"), researchers can now observe millions of cells simultaneously as they develop into a new organ-for example, a pancreas.

23 Jan 2025

Ancient viral DNA plays crucial role in early embryo development

Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life.

20 Jan 2025

Bidirectional movement drives DNA loop formation

Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction. Until now, researchers believed that these so-called SMC motors that make loops into DNA could move in one direction only. The discovery, which is published in Cell, is key to understanding how these motors shape our genome and regulate our genes.

17 Jan 2025

Study unveils role of TLE6 in male sperm development

Infertility is a major global challenge associated with physiological and psychological impact. Genetic mutations that affect early embryonic development, oocyte (egg cell) maturation, and fertilization have recently been studied as causes of infertility.

16 Jan 2025

AI reveals key follicle sizes to boost IVF success

Researchers utilize explainable artificial intelligence to identify follicle sizes important for relevant downstream clinical outcomes during assisted conception.

14 Jan 2025

A large-scale tongue cancer organoid library for precision oncology

Oral cancer is an increasingly prevalent disease worldwide, with over 300,000 new cases diagnosed each year. Among oral cancers, tongue cancer (TC) is the most common type and often carries a poor prognosis. Surgery combined with chemoradiotherapy is one of the main lines of treatment for high-risk cases of TC.

9 Jan 2025

AI analysis reveals optimal follicle sizes for IVF success

During IVF treatment, doctors use ultrasound scans to monitor the size of follicles - small sacs in the ovaries containing eggs - to decide when to give a hormone injection known as the 'trigger' to prepare the eggs for collection and ensure that they are ready to be fertilised with sperm to create embryos.

8 Jan 2025

Innovative AI approach enhances imaging in thick biological samples

Depth degradation is a problem biologists know all too well: The deeper you look into a sample, the fuzzier the image becomes.

7 Jan 2025

New therapies and technologies provide hope for age-related fertility challenges

Scientists explore emerging strategies to combat reproductive aging, highlighting promising therapies and technologies to improve fertility in later life.

17 Dec 2024

Researchers uncover key mechanisms in blood vessel formation

The formation of blood vessels is a complex process involving the interplay of proteins and mechanic forces.

17 Dec 2024

Researchers discover key genetic mechanism behind craniofacial development

An international team of researchers has identified a key genetic mechanism that regulates the formation and migration of cranial neural crest cells, which are essential for developing facial structures.

14 Dec 2024

Potential new mRNA-based therapy for pre-eclampsia

Lipid nanoparticles targeting VEGF mRNA show promise in treating pre-eclampsia, restoring maternal blood pressure and enhancing fetal health in murine models.

13 Dec 2024

University of Arizona receives $1.7 million for spina bifida research

Researchers at the University of Arizona College of Medicine – Tucson received $1.7 million in funding from the Centers for Disease Control and Prevention to improve knowledge regarding the prevalence, mortality and health outcomes for people of all ages living with spina bifida.

2 Dec 2024

Placental defects linked to congenital heart defects

Congenital heart defects are the most common form of human birth defect, but we still don't fully understand what causes them.

26 Nov 2024

Pcdh8 gene suppression critical for zebrafish notochord formation

Can a single protein-encoding gene determine whether a vertebrate embryo develops normally? Yes, according to Osaka Metropolitan University researchers, who found that suppression of Pcdh8 is essential for the notochord to elongate properly in zebrafish.

21 Nov 2024

Advances in the surgical management of gastroschisis

Gastroschisis, a congenital abdominal wall defect, has transformed from a uniformly fatal condition to one with a 95% survival rate through surgical advancements over the past six decades.

8 Nov 2024

Study supports very early abortion for women seeking termination

Clinics and hospitals currently defer medication abortion until ultrasound confirms a pregnancy inside the uterus.

6 Nov 2024

Saturated fats accelerate neurodegeneration in multiple sclerosis

Targeting ceramide synthase enzymes may reduce multiple sclerosis severity by limiting ceramide C16 synthesis, offering potential neuroprotective strategies.

6 Nov 2024

Rare neural crest stem cells identified as key drivers of cellular reprogramming

A team led by researchers at the University of Toronto has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of reprogrammed neurons found by other researchers.

3 Nov 2024

New imaging method could transform gene expression research

They say a picture is worth a thousand words. A new method, developed by University of Michigan researchers, creates images that are worth many gigabytes of data, which could revolutionize the way biologists study gene expression. Seq-Scope, developed by Jun Hee Lee, Ph.D., Hyun Min Kang, Ph.D., and their colleagues, was first described in Cell in 2021 as the first method to analyze gene expression at sub micrometer-scale spatial resolution.

1 Nov 2024