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Electro-acupuncture shows promise in obesity management

A team of scientists led by Nanyang Technological University Singapore (NTU Singapore) and Hong Kong University (HKU) has found evidence that electro-acupuncture - a form of traditional Chinese medicine (TCM) treatment - could be used to manage obesity.

8 Oct 2024

New study explores UBA1 dysfunction in VEXAS and cancer

A new research perspective was published in Oncotarget's Volume 15 on September 30, 2024, entitled, "UBA1 dysfunction in VEXAS and cancer."

3 Oct 2024

Scientists uncover role of Wnt in kidney formation

A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life. Scientists have been studying Wnt actions for four decades to comprehend its complex roles in development and disease.

1 Oct 2024

Macrophage memory following COVID infection provides cross-virus protection

More than 200 viruses can infect and cause disease in humans; most of us will be infected by several over the course of a lifetime.

30 Sep 2024

Why children with Down’s syndrome are predisposed to developing leukaemia

The study uncovers mechanisms linking Down syndrome to leukemia, emphasizing the role of oxidative stress and genetic alterations in fetal blood development.

26 Sep 2024

Extracellular vesicles play key role in brain development

Extracellular vesicles (EVs) are tiny bubbles released by cells, acting as cargo vessels through which cells exchange signals and thus communicate.

25 Sep 2024

Promising antidepressant offers hope for glioblastoma treatment

Glioblastoma is a particularly aggressive brain tumor that at present is incurable. Cancer doctors can extend patients' life expectancy through operations, radiation, chemotherapy or surgical interventions. Nevertheless, half of patients die within twelve months of diagnosis.

20 Sep 2024

$1 million grant awarded to explore myelin repair mechanisms in multiple sclerosis

The National Multiple Sclerosis Society (USA) has awarded a grant of 1 million dollars to Dr. Isabel Pérez-Otaño, who leads the Plasticity and Remodeling of Neural Circuits laboratory at the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche.

18 Sep 2024

The Key Role of iPSC-Derived Microglia in Research and Drug Discovery

Dr. Tilman explains the functions of iPSC-derived microglia and their relevance to conditions like Alzheimer’s.

From Axol Bioscience Ltd 17 Sep 2024

C1QL1 protein identified as key to myelin replacement

The neurons of the brain are protected by an insulating layer called myelin. In certain diseases like multiple sclerosis, this protective layer is damaged and lost, leading to death of neurons and disability.

11 Sep 2024

Cancer drug offers life-changing results for severe lupus patient

The team at Charité – Universitätsmedizin Berlin is astounded by the huge improvement seen in a female patient with severe systemic lupus erythematosus (SLE) after being treated with the cancer medication teclistamab. Not long ago, the 23-year-old was wheelchair-bound due to the autoimmune disease.

6 Sep 2024

Investigating inflammatory memory in hematopoietic stem cells within the AML niche

A new research perspective was published in Oncotarget's Volume 15 on September 4, 2024, entitled, "Trained and ready - the case for an inflammatory memory for hematopoietic stem and progenitor cells in the AML niche."

5 Sep 2024

Astrocytes reprogrammed to brain stem cells through methylation

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain.

4 Sep 2024

Autophagy in HPCs modulates exosomal miRNAs to inhibit liver fibrosis

The study investigates the role of autophagy in hepatic progenitor cells (HPCs) and its potential to modulate exosomal microRNAs (miRNAs) to inhibit liver fibrosis in the context of schistosomiasis, a disease caused by parasitic flatworms that can lead to severe organ damage, particularly to the liver.

2 Sep 2024

Distinct waves of T cells generated by each dose of combination immunotherapy

A new tool for monitoring immune health patterns over time has revealed how a pair of checkpoint inhibitor therapies works together to recruit new cancer-fighting T cells with every infusion.

29 Aug 2024

Temperature changes influence meiotic crossovers and chromosome organization in yeast

This study is led by Prof. Shunxin Wang (State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University) and Prof. Liangran Zhang (Advanced Medical Research Institute, Shandong University).

23 Aug 2024

Researchers reveal impact of genetic ancestry on breast cancer risk and cell diversity

Researchers map the diverse cell types present in healthy breast tissue to elucidate the role of genetic ancestry in breast cancer risk.

20 Aug 2024

Breakthrough in tissue engineering using bacteria

A research team at the Technical University of Denmark, led by Alireza Dolatshahi-Pirouz, has recently uncovered new ground in tissue engineering and cell therapy by harnessing the healing power of bacteria.

19 Aug 2024

New histone tag discovery offers hope for myelin repair in neurodegenerative diseases

In a groundbreaking study, researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have identified a distinct histone tag in adult oligodendrocyte progenitor cells (OPCs) that may pave the way for innovative therapies targeting myelin repair, a critical target for several neurodegenerative and psychiatric disorders, including multiple sclerosis, Alzheimer's disease, and schizophrenia.

12 Aug 2024

The interplay of liver cancer stem cells and immune cells in tumor microenvironment

The complex dynamics between liver cancer stem cells (CSCs) and immune cells within the tumor microenvironment (TME) are central to the progression of liver cancer. These interactions are critical in creating an immunosuppressive setting that significantly impacts the response to immunotherapy. Liver CSCs, responsible for tumor initiation, metastasis, therapeutic resistance, and recurrence, exhibit heterogeneity and are characterized by various surface markers that contribute to their stemness and metastatic potential.

7 Aug 2024