Laboratory News and Research

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Comparative study finds higher rates of adverse events with ticagrelor

One year of treatment with either of two strong blood-thinning medications—ticagrelor and prasugrel—by people with type 1 or type 2 diabetes who had a drug-eluting stent placed in their heart to treat coronary artery blockages did not offer the same level of benefit to prevent stent clotting, heart attacks, and bleeding complications, according to findings presented during a preliminary late-breaking science session during the American Heart Association's Scientific Sessions 2025 in New Orleans on November 10.

10 Nov 2025

Green-synthesized nanoparticles enhance cidofovir's anticancer efficacy

In this study, led by Nahid Shahabadi from Razi University in Kermanshah, researchers developed an environmentally friendly approach to enhance the performance of cidofovir, a drug used to treat infections caused by DNA viruses. The work responds to the growing need for therapies that are safer, more effective, and better targeted.

10 Nov 2025

Study identifies thyroid hormone pathway as key player in prostate cancer development

A hormone produced in the thyroid gland can play a key role in the development of prostate cancer.

10 Nov 2025

New diagnostic approach identifies dementia stages based on neurovascular and metabolic changes

Researchers from the Indiana University School of Medicine have developed a highly sensitive diagnostic that predicts a person's stage of dementia based on neurovascular and metabolic changes.

10 Nov 2025

Death risk found to be six times higher among hospitalized patients with dyspnea

The risk of dying is six times higher among patients who become short of breath after being admitted to hospital, according to research published today (Monday) in ERJ Open Research. Patients who were in pain were not more likely to die.

10 Nov 2025

Why talking to yourself in third person can help you feel better before big moments

Researchers studying over 20,000 daily experiences found that people mostly talk to themselves in the first person, while using third-person, distanced self-talk far less often. Yet when they do, this detached inner voice offers a small but real emotional boost, especially when preparing for upcoming actions or performances.

9 Nov 2025

OSU researchers design a highly effective, low-dose, manganese-MOF MRI agent

Scientists at Oregon State University have filed a patent on a design for a new magnetic resonance imaging contrast agent with the potential to outperform current agents while being less toxic to patients and more environmentally friendly.

7 Nov 2025

New radioimmunotherapy approach shows potential to cure HER2-positive breast cancer

A new radioimmunotherapy approach has the potential to cure human epidermal growth factor receptor 2 (HER2)-positive breast cancer, according to new research published in the November issue of The Journal of Nuclear Medicine.

7 Nov 2025

Rockefeller scientists engineer next-generation antibody to replace IVIG therapy

Intravenous immunoglobulin (IVIG) therapy involves infusing patients with naturally occurring IgG antibodies to treat autoimmune conditions.

7 Nov 2025

Study reveals structural and cellular clues behind cancer-linked GnT-V enzyme selectivity

Glycans are important complex carbohydrates found on cell surfaces that serve crucial roles in cell-to-cell communication, structure, and protection.

7 Nov 2025

Exploring endogenous retroviruses as hidden drivers of alcohol use disorder

Alcohol use disorder (AUD), characterized by uncontrollable alcohol consumption due to physical and psychological dependence, affects approximately 14.1 million people in the U.S.

7 Nov 2025

Mapping the brain's body regulation and sensing system using 7 Tesla MRI

Jiahe Zhang, PhD, of the Department of Psychiatry at Mass General Brigham, is the lead author of the paper published in Nature Neuroscience, "Cortical and subcortical mapping of the human allostatic-interoceptive system using 7 Tesla fMRI."

7 Nov 2025

Diabetes drug blunts exercise-induced health improvements

A widely prescribed diabetes drug may be sabotaging one of the most trusted strategies for preventing the disease: exercise.

7 Nov 2025

New initiative focuses on advancing human disease research through AI and frontier biology

Mark Zuckerberg and Priscilla Chan today announced the launch of a first-of-its-kind initiative combining frontier artificial intelligence and frontier biology to dramatically accelerate scientific progress toward understanding and addressing human disease.

7 Nov 2025

Study reveals tumor defense mechanisms in colorectal cancer

Colorectal cancer is one of the leading causes of cancer death worldwide. In recent years, immunotherapies-treatments that reactivate the immune system to attack tumor cells-have transformed the treatment of many types of cancer.

7 Nov 2025

Intensive mind-body retreat rapidly alters brain function and blood biology

Researchers at the University of California San Diego have found that an intensive retreat combining multiple mind-body techniques, including meditation and healing practices, produced rapid and wide-ranging changes in brain function and blood biology.

6 Nov 2025

Five-year project seeks new weapons against drug-resistant bacteria

Lethal lettuce in Missouri. Murderous onions in Colorado. To biochemists at the University of Oklahoma, these aren't just headlines – they're warnings of the risks posed by drug-resistant bacteria and the human cost of inaction.

6 Nov 2025

Engineered biomaterial promotes formation of cancer-fighting immune cell clusters

Researchers at Moffitt Cancer Center have developed a novel biomaterial-based system that induces the formation of tertiary lymphoid-like structures, or TLSs.

6 Nov 2025

Scientists map gut microbiota associated with coronary artery disease

Nearly 20 million people die every year from cardiovascular diseases, the leading cause of death worldwide.

6 Nov 2025

Scientists map kinesin-2 tail structure to understand cargo binding

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo remained a mystery. The new study provides a key piece of this puzzle by revealing the atomic-level structure of the kinesin-2 tail and its interaction with cargo and adaptor proteins.

6 Nov 2025

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Laboratory News and Research

Comparative study finds higher rates of adverse events with ticagrelor

Green-synthesized nanoparticles enhance cidofovir's anticancer efficacy

Study identifies thyroid hormone pathway as key player in prostate cancer development

New diagnostic approach identifies dementia stages based on neurovascular and metabolic changes

Death risk found to be six times higher among hospitalized patients with dyspnea

Why talking to yourself in third person can help you feel better before big moments

OSU researchers design a highly effective, low-dose, manganese-MOF MRI agent

New radioimmunotherapy approach shows potential to cure HER2-positive breast cancer

Rockefeller scientists engineer next-generation antibody to replace IVIG therapy

Study reveals structural and cellular clues behind cancer-linked GnT-V enzyme selectivity

Exploring endogenous retroviruses as hidden drivers of alcohol use disorder

Mapping the brain's body regulation and sensing system using 7 Tesla MRI

Diabetes drug blunts exercise-induced health improvements

New initiative focuses on advancing human disease research through AI and frontier biology

Study reveals tumor defense mechanisms in colorectal cancer

Intensive mind-body retreat rapidly alters brain function and blood biology

Five-year project seeks new weapons against drug-resistant bacteria

Engineered biomaterial promotes formation of cancer-fighting immune cell clusters

Scientists map gut microbiota associated with coronary artery disease

Scientists map kinesin-2 tail structure to understand cargo binding

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