Genes News and Research

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New understanding of keratin 17 protein could lead to development of better ways to prevent cancer

New research from the Johns Hopkins Bloomberg School of Public Health suggests that the protein keratin 17 - the presence of which is used in the lab to detect and stage various types of cancers - is not just a biomarker for the disease, but may play a critical role in tumor growth.

14 Jul 2015

University of Leeds scientists uncover genes implicated in common inherited diseases

Scientists from the University of Leeds have uncovered the most comprehensive list yet of genes implicated in a group of common inherited diseases.

14 Jul 2015

UM researchers discover new gene behind neurodegenerative conditions

Researchers at the University of Miami have discovered and characterized a previously unknown disease gene linked to the degeneration of optic and peripheral nerve fibers. The study titled "Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder" is published in the journal Nature Genetics.

14 Jul 2015

Gene function in the human brain could help reveal basis of autism

UNSW Australia scientists have discovered a link between autism and genetic changes in some segments of DNA that are responsible for switching on genes in the brain.

14 Jul 2015

Researchers identify protein responsible for preserving antibody-producing cells that lead to long-term immunity

Melbourne researchers have identified a protein responsible for preserving the antibody-producing cells that lead to long-term immunity after infection or vaccination.

14 Jul 2015

UMass Amherst scientist to study how estrogen-mimicking chemicals in the womb can increase breast cancer risk

Much attention has been paid to genetics in breast cancer as disease rates rise, but most women have no family history of the disease, suggesting that there is an environmental risk we don't yet understand, says environmental health scientist Laura Vandenberg in the School of Public Health and Health Sciences at the University of Massachusetts Amherst.

13 Jul 2015

Canadian researchers launch world's first viral therapy clinical trial to attack and kill cancer cells

Canadian researchers have launched the world's first clinical trial of a novel investigational therapy that uses a combination of two viruses to attack and kill cancer cells, and stimulate an anti-cancer immune response. Previous research by this team and others worldwide suggests that this approach could be very powerful, and could have fewer side effects than conventional chemotherapy and radiation, although it will take years to rigorously test through this trial and others.

13 Jul 2015

Shape of the cerebral cortex strongly correlates with genetic ancestry

Researchers at the University of California, San Diego and the School of Medicine have found that the three-dimensional shape of the cerebral cortex - the wrinkled outer layer of the brain controlling many functions of thinking and sensation - strongly correlates with ancestral background.

12 Jul 2015

Scientists uncover new genes that affect development and maintenance of blood stem cell

Even though the transplantation of blood stem cells, also known as bone marrow, has saved many lives over many decades, the genes that control the number or function of blood stem cells are not fully understood. In a study published in June in Stem Cell Reports, the USC Stem Cell labs of Hooman Allayee and Gregor Adams uncovered new genes that affect blood stem cell development and maintenance.

12 Jul 2015

Middle classes from developing countries more vulnerable to develop diabetes due ancestral diets

The middle classes from developing countries are more susceptible than western Caucasians to obesity, type 2 diabetes and cardiovascular disease in today's changing environment. New research published today in Cell Metabolism from the University of Sydney in Australia, the National Centre for Cell Science and the DYP Medical College in Pune, India reveals this may be a result of the nutrition endured by their ancestors.

12 Jul 2015

Study discovers potential link between inherited genome-wide DNA sequences and CAD

A study to examine recessively inherited genome-wide DNA sequences has for the first time discovered a potential link with Britain's biggest killer - Coronary Artery Disease (CAD).

10 Jul 2015

Vanderbilt receives $12.8 million federal grant to develop better ways to predict effects of drugs in patients

Vanderbilt University Medical Center has received a five-year, $12.8 million grant from the federal government to develop better ways to predict how patients will respond to the drugs they're given.

10 Jul 2015

Cedars-Sinai scientists identify genes responsible for tumor growth in high grade brain tumors

After generating new brain tumor models, Cedars-Sinai scientists in the Board of Governors Regenerative Medicine Institute identified the role of a family of genes underlying tumor growth in a wide spectrum of high grade brain tumors.

10 Jul 2015

Molecular cancer expert David Livingston named recipient of Basser Global Prize

The Basser Center for BRCA at Penn's Abramson Cancer Center has announced the recipient of its third annual Basser Global Prize. The honor will go to molecular cancer expert David Livingston, MD, Emil Frei Professor of Genetics and Medicine at Harvard Medical School, and deputy director of the Dana-Farber/Harvard Cancer Center.

10 Jul 2015

Researchers identify five recurrent fusion genes involved in acute gastritis and cancer

Studying the gastric cancers of 15 Southeast Asian patients, researchers at The Jackson Laboratory, the Genome Institute of Singapore and other institutions identified five recurrent fusion genes, one of which appears to lead to cellular changes involved in acute gastritis and cancer.

10 Jul 2015

Research: Jumping genes may be responsible for genetic chaos behind oesophageal cancer cases

CANCER RESEARCH UK scientists have found that 'jumping genes' may add to the genetic chaos behind more than three-quarters of oesophageal cancer cases, according to research published in BMC Genomics today (Friday).

10 Jul 2015

New UCLA study reveals genetic architecture of schizophrenia

A new study by UCLA scientists adds to the understanding of the genetic architecture of schizophrenia. Past research has shown the impact of commonly occurring genetic variants on a person's risk of developing schizophrenia. This new study focused instead on rare coding mutations that affect protein function. It found that patients with schizophrenia have a higher-than-normal share of these mutations.

9 Jul 2015

Huntsman Cancer Institute receives NCI's Comprehensive Cancer Center designation

The National Cancer Institute has awarded Huntsman Cancer Institute at the University of Utah its Comprehensive Cancer Center status, the highest designation possible.

9 Jul 2015

Researchers discover molecule that may favour production of induced pluripotent cells

Since 2006, research has succeeded in generating, from specialised adult cells, induced pluripotent cells (iPS cells), with huge potential applications, particularly for regenerative medicine. However, the process has still not been completely mastered. Two teams of researchers from Inserm, CNRS, Centre Léon Bérard and Claude Bernard Lyon 1 University have discovered a molecule that may favour the production of these induced stem cells.

9 Jul 2015

Vanderbilt investigators develop potential antibody treatments against chikungunya

In late 2013 the Caribbean had its first case of the mosquito-borne chikungunya virus. Today there have been almost 1.2 million cases in 44 countries or territories, including 177 cases in 31 U.S. States. Vanderbilt University Medical Center's James Crowe, M.D., Ann Scott Carell Professor and director of the Vanderbilt Vaccine Center, and his team are reporting the first large panel of antibody treatments against this disease in the current issue of Cell Host and Microbe.

9 Jul 2015

Genes News and Research

New understanding of keratin 17 protein could lead to development of better ways to prevent cancer

University of Leeds scientists uncover genes implicated in common inherited diseases

UM researchers discover new gene behind neurodegenerative conditions

Gene function in the human brain could help reveal basis of autism

Researchers identify protein responsible for preserving antibody-producing cells that lead to long-term immunity

UMass Amherst scientist to study how estrogen-mimicking chemicals in the womb can increase breast cancer risk

Canadian researchers launch world's first viral therapy clinical trial to attack and kill cancer cells

Shape of the cerebral cortex strongly correlates with genetic ancestry

Scientists uncover new genes that affect development and maintenance of blood stem cell

Middle classes from developing countries more vulnerable to develop diabetes due ancestral diets

Study discovers potential link between inherited genome-wide DNA sequences and CAD

Vanderbilt receives $12.8 million federal grant to develop better ways to predict effects of drugs in patients

Cedars-Sinai scientists identify genes responsible for tumor growth in high grade brain tumors

Molecular cancer expert David Livingston named recipient of Basser Global Prize

Researchers identify five recurrent fusion genes involved in acute gastritis and cancer

Research: Jumping genes may be responsible for genetic chaos behind oesophageal cancer cases

New UCLA study reveals genetic architecture of schizophrenia

Huntsman Cancer Institute receives NCI's Comprehensive Cancer Center designation

Researchers discover molecule that may favour production of induced pluripotent cells

Vanderbilt investigators develop potential antibody treatments against chikungunya

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