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SARS-CoV-2 protein interactions with viral and host RNAs in authentic virus-infected cells

Researchers investigated protein interactions of SARS-CoV-2 with host and viral RNAs in infected cells.

1 Mar 2022

Adding immunotherapy drug to standard head and neck cancer treatment increases patient survival

A University of Cincinnati clinical trial that added an immunotherapy drug to standard of care treatment regimens has shown increased survival rates for head and neck cancer patients with intermediate risk features.

1 Mar 2022

Biophysical fitness profile of SARS-CoV-2 Delta variant

In a recent study posted to the bioRxiv* preprint server, researchers investigated the biophysical fitness landscape of the receptor-binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant.

1 Mar 2022

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated the potent neutralizing ability of a polyclonal equine antibody (Ab), FBR-002, against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs), including Omicron.

28 Feb 2022

Researchers demonstrate the powerful gene silencing effects of HDO technology

T and B lymphocytes, which are part of a group of immune cells commonly called white blood cells, work together to eliminate foreign invaders in the body such as viruses.

28 Feb 2022

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

28 Feb 2022

Harvard researcher develops new model system to illuminate the fundamentals of aging

Huge amounts of time and money have been devoted to finding treatments for diseases that become more common as we age, like cancer and Alzheimer's.

28 Feb 2022

Novel respiratory model predicts mechanisms altered by SARS-CoV-2 variants

Researchers study cell infection and viral replication methods affected by SARS-CoV-2 mutations through a novel respiratory model.

28 Feb 2022

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

28 Feb 2022

A study on the evolution of avian coronavirus escape mutants in vitro

A recent study included an in vitro assessment of the effect of antibody titers and vaccine combinations on the emergence of escape mutants of AvCoV.

28 Feb 2022

Study compares heterologous and homologous third vaccination in kidney transplant recipients

A new study assesses the comparative neutralizing antibody level elicited by three mRNA vaccine doses to a heterologous COVID-19 vaccine regimen.

28 Feb 2022

Researchers report a new, more efficient way to grow breast cancer models

For years, researchers at Huntsman Cancer Institute at the University of Utah have honed a process of developing breast cancer models using tumors donated by breast cancer patients, which they then implant into mice as a way to study the tumor's behavior.

28 Feb 2022

Researchers show a relationship between regionalized myocardial fibrosis and mitral valve prolapse

The larger the sail, the more wind it catches. But as that size increases, so does the stress experienced by each sheet and line connected to the canvas.

28 Feb 2022

Novel molecular pathway shared by two neurodegenerative disorders discovered

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

28 Feb 2022

NYITCOM researchers secure NIH grant to investigate diabetic heart failure treatments

A research team from New York Institute of Technology College of Osteopathic Medicine, led by Biomedical Sciences Instructor Satoru Kobayashi, Ph.D., has secured a grant from the National Institutes of Health National Heart, Lung, and Blood Institute.

28 Feb 2022

MUSC study sheds light on better ways to prevent and treat colorectal cancer

An MUSC Hollings Cancer Center study sheds light on better ways to prevent and treat colorectal cancer, which often is found at advanced stages when it's much harder to treat.

28 Feb 2022

New data analysis tool reveals immune cell types associated with COVID-19 mortality risk

A new data analysis tool developed by Yale researchers has revealed the specific immune cell types associated with increased risk of death from COVID-19, they report Feb. 28 in the journal Nature Biotechnology.

28 Feb 2022

Novel mechanism that connects circadian rhythm and muscle repair discovered

Northwestern Medicine investigators have discovered a novel mechanism that connects circadian rhythm-controlled cellular metabolism and regeneration with muscle repair after injury, according to recent findings published in the journal Genes and Development.

28 Feb 2022

Study reveals new way viruses trigger autoimmunity

Autoimmune diseases such as rheumatoid arthritis and Type 1 diabetes are thought to arise when people with a genetic susceptibility to autoimmunity encounter something in the environment that triggers their immune systems to attack their own bodies.

28 Feb 2022

New imaging approach provides a clearer ‘picture’ of blood vessels in health and disease

Johns Hopkins Medicine researchers have developed and tested a new imaging approach they say will accelerate imaging-based research in the lab by allowing investigators to capture images of blood vessels at different spatial scales.

28 Feb 2022

Cell News and Research

SARS-CoV-2 protein interactions with viral and host RNAs in authentic virus-infected cells

Adding immunotherapy drug to standard head and neck cancer treatment increases patient survival

Biophysical fitness profile of SARS-CoV-2 Delta variant

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

Researchers demonstrate the powerful gene silencing effects of HDO technology

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Harvard researcher develops new model system to illuminate the fundamentals of aging

Novel respiratory model predicts mechanisms altered by SARS-CoV-2 variants

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

A study on the evolution of avian coronavirus escape mutants in vitro

Study compares heterologous and homologous third vaccination in kidney transplant recipients

Researchers report a new, more efficient way to grow breast cancer models

Researchers show a relationship between regionalized myocardial fibrosis and mitral valve prolapse

Novel molecular pathway shared by two neurodegenerative disorders discovered

NYITCOM researchers secure NIH grant to investigate diabetic heart failure treatments

MUSC study sheds light on better ways to prevent and treat colorectal cancer

New data analysis tool reveals immune cell types associated with COVID-19 mortality risk

Novel mechanism that connects circadian rhythm and muscle repair discovered

Study reveals new way viruses trigger autoimmunity

New imaging approach provides a clearer ‘picture’ of blood vessels in health and disease

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