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Researchers develop new precision medicine technology for cancer immunotherapy

In recent years, great advances have been made in the development of new successful immunotherapies to treat cancer. CAR T-cell therapy and antibody treatments are two types of targeted immunotherapies that have revolutionized areas of cancer care.

28 Feb 2022

Histopathologic and molecular effects in the placenta after SARS-CoV-2 infection during pregnancy

A recent study evaluated the molecular and histopathological effects in the placenta following a SARS-CoV-2 infection during pregnancy.

28 Feb 2022

Immunity before and after the SARS-CoV-2 Omicron variant in South Africa

Researchers conducted a national epidemiological survey to determine the seropositivity against SARS-CoV-2 before the emergence of the novel Omicron variant of concern.

28 Feb 2022

Peptide-based vaccine fails to protect mice against SARS-CoV-2 despite T cell response

A recent study observed that peptide-based vaccination against SARS-CoV-2 failed to protect mice against COVID-19, albeit eliciting T cell responses.

28 Feb 2022

ESMO announces a new series of resources to guide physicians in oncological practice

ESMO, the leading professional organization for medical oncology, announces a new series of resources designed to guide physicians in areas of oncological practice not covered by guidelines, where current evidence is insufficient to evenly inform clinical decision-making.

28 Feb 2022

Health events amongst pregnant females after COVID-19 vaccination

Researchers evidenced that mRNA-based COVID-19 vaccines are safe in pregnancy, with lower rates of significant AEFIs in pregnant women than non-pregnant females.

28 Feb 2022

Triple antibody cocktail is a promising candidate for immunotherapy against SARS-CoV-2 variants of concern

Researchers generated a panel of bnAbs against SARS-CoV, SARS-CoV-2, and its variant VOCs, including Omicron from sequentially immunized mice.

28 Feb 2022

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Researchers emphasized the need to take on a holistic and unbiased approach to develop a universal vaccine for coronaviruses, including SARS-CoV-2, which is a biomedical priority during the ongoing COVID-19 pandemic.

28 Feb 2022

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Researchers evaluated the pathogenicity and replication potential of SARS-CoV-2 VOC Omicron lineage, BA.2 in immunocompetent mice and hamsters.

28 Feb 2022

Noncovalent protease inhibitors against SARS-CoV-2 and other coronaviruses

In a new study published in ACS Infectious Diseases journal, scientists biochemically and structurally evaluated the PLpro from a subgroup 2b bat coronavirus, BtSCoV-Rf1.2004, to identify unique structural features or enzymatic biases of the subgroup 2b.

28 Feb 2022

Will Omicron BA.2 become the next dominant variant?

A new study presents a comprehensive analysis of the potential of both Omicron BA.2 and BA.3 to become the next dominant circulating SARS-CoV-2 strain.

27 Feb 2022

Emergence of SARS-CoV-2 Omicron likely due to immune selective pressure

A new study discusses the emergence of new variants of SARS-CoV-2 that can escape antibody-mediated neutralization, as opposed to other Sarbecoviruses.

27 Feb 2022

Mechanism behind how certain osmolytes cause kidney damage revealed

Researchers from Tokyo Metropolitan University have uncovered the mechanism by which osmolytes used to treat high fluid pressure in the eye and skull can cause kidney damage.

27 Feb 2022

Altered microbiomes in SARS-CoV-2 infection pose threat of antibiotic resistance

A new study discusses changes in the microbiota of various parts of the body with SARS-CoV-2 infection.

27 Feb 2022

A promising new vaccine for SARS-CoV-2 and influenza

Researchers create a vaccine candidate that could protect against both SARS-CoV-2 and IAVs.

27 Feb 2022

Harvard’s new kidney engineering technology licensed to San Diego-based Trestle Biotherapeutics

A newly launched startup is building upon innovations developed over several years at the Wyss Institute for Biologically Inspired Engineering at Harvard University, Harvard John A. Paulson School of Engineering & Applied Sciences (SEAS), and Brigham and Women’s Hospital (Brigham) to engineer functional kidney tissue for renal repair and replacement therapy.

25 Feb 2022

Unexpected discovery could open the door to new treatment for small-cell lung cancer

An unexpected discovery at UVA Cancer Center has allowed scientists to halt the development of small-cell lung cancer in lab mice, and the surprise finding could open the door to a new treatment approach in people.

25 Feb 2022

Spectacular structure of C.difficile's protective armor revealed

The spectacular structure of the protective armor of superbug C.difficile has been revealed for the first time showing the close-knit yet flexible outer layer – like chain mail.

25 Feb 2022

LJI researchers discover new genes in CD4+ "helper" T cell subsets

T cells play important roles in helping to fight infections and cancers - and they can also drive autoimmune diseases. Now researchers at La Jolla Institute for Immunology (LJI) have discovered new genes in CD4+ "helper" T cell subset that are linked to risk of autoimmune diseases.

25 Feb 2022

Targeting a specific protein can help prevent or delay prostate cancer progression

Targeting a specific protein that is often overexpressed in prostate cancer can help prevent or delay the disease from spreading to other parts of the body, according to a study led by Cedars-Sinai Cancer investigators.

25 Feb 2022

Cell News and Research

Researchers develop new precision medicine technology for cancer immunotherapy

Histopathologic and molecular effects in the placenta after SARS-CoV-2 infection during pregnancy

Immunity before and after the SARS-CoV-2 Omicron variant in South Africa

Peptide-based vaccine fails to protect mice against SARS-CoV-2 despite T cell response

ESMO announces a new series of resources to guide physicians in oncological practice

Health events amongst pregnant females after COVID-19 vaccination

Triple antibody cocktail is a promising candidate for immunotherapy against SARS-CoV-2 variants of concern

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Noncovalent protease inhibitors against SARS-CoV-2 and other coronaviruses

Will Omicron BA.2 become the next dominant variant?

Emergence of SARS-CoV-2 Omicron likely due to immune selective pressure

Mechanism behind how certain osmolytes cause kidney damage revealed

Altered microbiomes in SARS-CoV-2 infection pose threat of antibiotic resistance

A promising new vaccine for SARS-CoV-2 and influenza

Harvard’s new kidney engineering technology licensed to San Diego-based Trestle Biotherapeutics

Unexpected discovery could open the door to new treatment for small-cell lung cancer

Spectacular structure of C.difficile's protective armor revealed

LJI researchers discover new genes in CD4+ "helper" T cell subsets

Targeting a specific protein can help prevent or delay prostate cancer progression

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