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AI could lead to better ways to predict the onset and course of cardiovascular disease

For the first time, University of Utah Health scientists have shown that artificial intelligence could lead to better ways to predict the onset and course of cardiovascular disease.

20 Jan 2022

Study: Nearly 30% of people with blinding retinal disease can safely stop eye injection therapy

In a preliminary study of 106 people with "wet" age-related macular degeneration, Johns Hopkins Medicine researchers report that as many as a third of those with the blinding retinal disease may someday be able to safely stop eye injection therapy without further vision loss.

18 Jan 2022

SARS-CoV-2 interacts with heparan sulfate to activate the alternative pathway

A new study discusses the activation of the complement system to determine its role in COVID-19-related deaths.

17 Jan 2022

Research could advance the understanding of links between heart disease and dementia

Heart disease can directly cause brain dysfunction early on which could lead to dementia and can treble the amount of an Alzheimer's protein in the brain, say scientists.

13 Jan 2022

Long-term use of blood pressure medication could be contributing to kidney damage

New kidney research from the University of Virginia School of Medicine is raising concerns that long-term use of drugs commonly prescribed to treat high-blood pressure and heart failure could be contributing to kidney damage.

12 Jan 2022

Study finds a subset of vascular macrophages to be powerful ally in the fight against atherosclerosis

A new study reveals the existence of a powerful ally in the fight against cardiovascular disease, a protective subset of vascular macrophages expressing the C-type lectin receptor CLEC4A2, a molecule which fosters "good" macrophage behavior within the vessel wall.

11 Jan 2022

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Not too long ago the idea of taking, for instance a skin cell and transforming it into a muscle cell was unthinkable. About 10 years ago, however, revolutionary research showed that it is indeed possible to reprogram differentiated adult cells into other types fully capable of conducting new functions.

6 Jan 2022

Melatonin found to inhibit SARS-CoV-2 entry into mice brains

New research recently unveiled the utility of melatonin and melatonin-derived medicines in reducing brain entry of severe acute respiratory syndrome coronavirus 2 and subsequently preventing long-term neurological consequences of coronavirus disease 2019.

6 Jan 2022

Folic acid-like drug reprograms DNA methylome of aggressive brain tumors

A folic acid-like drug, L-methylfolate, when administered alongside the standard therapy for patients with recurrent glioblastoma, changed aDNA process within their brain tumors, according to results from a phase 1 clinical trial.

5 Jan 2022

Researchers customize finger clip device to provide a noninvasive way for measuring blood pressure

Monitoring a person's blood pressure on a regular basis can help health care professionals with early detection of various health problems such as high blood pressure, which has no warning signs or symptoms.

4 Jan 2022

Study uncovers new details behind inflammation that promotes cardiovascular disease

High cholesterol and inflammation are key drivers of heart disease, and an inflamed buildup of lipids can cut off the blood supply through a coronary artery to cause a heart attack.

24 Dec 2021

Inhaled CBD shrinks glioblastoma’s size in an animal model

Inhaled CBD shrinks the size of the highly aggressive, lethal brain tumor glioblastoma in an animal model by reducing the essential support of its microenvironment, researchers report.

24 Dec 2021

X-ray imaging of cardiac tissue reveals the impact of Covid-19 on the heart

An interdisciplinary research team from the University of Göttingen and Hannover Medical School (MHH) has detected significant changes in the heart muscle tissue of people who died from Covid-19.

23 Dec 2021

Pandemic poses short- and long-term risks to babies, especially boys

The pandemic has created a hostile environment for pregnant people and their babies. Stress levels among expectant mothers have soared. Pregnant women with covid are five times as likely as uninfected pregnant people to require intensive care and 22 times as likely to die. Infected moms are four times as likely to have a stillborn child.

21 Dec 2021

SGLT2 inhibitor empagliflozin can be used to treat insulin resistance in the brain, finds study

Overweight or obesity, an unfavorable distribution of fat in the body and the development of type 2 diabetes are often associated with a reduced effect of the hormone insulin in many organs, including the brain (insulin resistance).

21 Dec 2021

New treatment could be a better option for patients with colon cancer

Targeted radioembolization alongside chemotherapy improved progress-free survival for patients with colon cancer that had metastasized to the liver, according to a study published in the Journal of Clinical Oncology.

17 Dec 2021

Novel technique developed to observe cancer cells’ metastatic potential

When cancer cells metastasize, they morph, becoming missile-shaped in order to penetrate into other tissues throughout the body.

16 Dec 2021

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

A gene that is overexpressed in some aggressive cancers also appears to be key to the excessive cell proliferation that thickens the walls of pulmonary arteries and ultimately causes the right ventricle of the heart to fail, scientists report.

16 Dec 2021

Study: Pregnant women with disabilities have increased risk for birth complications and death

Pregnant women with disabilities have a much higher risk for severe pregnancy- and birth-related complications and death than other pregnant women, according to findings by researchers at the National Institutes of Health.

15 Dec 2021

Discovery can pave the way for new strategies to reduce atherosclerosis using omega-3 fatty acids

A receptor activated by substances formed from omega-3 fatty acids plays a vital role in preventing inflammation in blood vessels and reducing atherosclerosis, a new study from Karolinska Institutet in Sweden published in The Journal of Clinical Investigation reports.